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Zidovudine

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Identification
Molecular formula
C10H13N5O4P
CAS number
30516-87-1
IUPAC name
[5-[(1-amino-2-formamido-ethylidene)amino]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate
State
State

Zidovudine is solid at room temperature.

Melting point (Celsius)
123.00
Melting point (Kelvin)
396.15
Boiling point (Celsius)
981.70
Boiling point (Kelvin)
1 254.85
General information
Molecular weight
267.24g/mol
Molar mass
267.2410g/mol
Density
1.4110g/cm3
Appearence

Zidovudine appears as a white to off-white, odorless crystalline powder.

Comment on solubility

Solubility of [5-[(1-amino-2-formamido-ethylidene)amino]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

The compound [5-[(1-amino-2-formamido-ethylidene)amino]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate, with the chemical formula C10H13N5O4P, exhibits interesting solubility characteristics that are worth exploring. Its solubility can be influenced by several factors, including:

  • Polarity: The presence of multiple functional groups, such as amino and hydroxyl groups, enhances the polarity of the molecule, potentially increasing its solubility in polar solvents like water.
  • pH Levels: As a phosphate compound, solubility may vary with changes in pH, allowing for more soluble forms in either acidic or basic environments.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds can significantly affect its solubility in aqueous solutions.
  • Temperature: Solubility often increases with temperature, so higher temperatures may lead to greater dissolution rates for this compound.

In summary, while the detailed solubility data for this specific compound may not be readily available, its structural features suggest a potential for reasonable water solubility, especially when considering the balance of hydrophilic functional groups present. Understanding these characteristics is essential for applications in biological systems or chemical processes.

Interesting facts

Interesting Facts About [5-[(1-amino-2-formamido-ethylidene)amino]-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate

This unique compound belongs to a class of molecules known as **phosphate esters** and carries significant biological relevance. Here are some intriguing aspects:

  • Biological Role: It is closely related to nucleotides, which are the building blocks of DNA and RNA. This relationship brings forth the possibility of playing a role in cellular processes.
  • Analog of Naturally Occurring Compounds: The structure of this compound suggests it could serve as an analog to other vital biomolecules. Therefore, it might be of interest in studies related to metabolic pathways.
  • Phosphate Groups: The presence of dihydrogen phosphate groups makes it a potential player in enzymatic reactions, particularly those involving phosphorylation and dephosphorylation, crucial processes in energy transfer in cells.
  • Research Potential: Due to its complex structure, this molecule may be investigated for its potential pharmaceutical applications, especially in targeting specific enzymes or receptors in various diseases.
  • Synthetic Routes: The synthesis of this compound might involve several interesting chemical reactions, reflecting synthetic methodologies that are applicable in organic chemistry research.

In conclusion, while the full scope of this compound's functionalities and applications is still being explored, its unique structure provides a fascinating ground for future research. As scientists continue to unravel its potential, it stands at the intersection of chemistry, biology, and medicine, promising various applications yet to be discovered.