Interesting facts
Interesting Facts about [(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
This complex compound, often referred to by its systematic name, showcases the intricate relationship between chemical structure and biological function. Here are some fascinating insights:
- Unique Structure: The compound features a tetracyclic framework, which is a rarity in organic chemistry. Such structures can often result in unique properties and potential biological activities.
- Potential as a Pharmaceutical: The presence of functional groups such as amino, methoxy, and carbamate suggests that this compound may have applications in medicinal chemistry, particularly in the design of new drugs.
- Chirality: With multiple chiral centers denoted by its stereochemical configurations, it is important to consider the impact of chirality on drug efficacy and safety. Different stereoisomers can exhibit significantly different biological activities.
- Complexity: The intricate combination of dual nitrogen content in the diazatetracycle and the multiple keto groups indicates a rich chemistry that may lead to diverse reactions and interactions.
- Biological Relevance: Compounds with similar structures have been studied for their roles in enzyme inhibition and as potential antibiotics or anticancer agents.
In the world of chemistry, compounds like this one remind us that the beauty of science lies in its complexity. Understanding their properties not only enhances our knowledge but also paves the way for innovative solutions in various fields, including pharmaceuticals and biochemistry.
Synonyms
mitomycin C
Mitomycin
50-07-7
Ametycine
Mutamycin
Mitomycin-C
Mitocin-C
Ametycin
Mytozytrex
Mitomycinum
Mytomycin
Mitomycinum C
Mitamycin
Mitozytrex
Mitosol
Muamycin
Mitomycyna C
7-Amino-9alpha-methoxymitosane
Mito-C
NSC-26980
Mit-C
MMC
RCRA waste number U010
NCI-C04706
CCRIS 414
HSDB 3239
NSC26980
EINECS 200-008-6
Mitomycine
UNII-50SG953SK6
JELMYTO
DTXSID2020898
CHEBI:27504
AI3-26199
Mitocin C
50SG953SK6
DTXCID00898
6-Amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-5-methylazirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione carbamate (ester)
Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS-(1aalpha,8beta,8aalpha,8balpha))-
UGN-101
UGN-102
Mitomycin [USAN:USP:INN:BAN]
Mitomycyna C [Polish]
MFCD00078109
[(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.0^{2,7}.0^{4,6}]trideca-1(9),11-dien-8-yl]methyl carbamate
Mitomicina
MITOMYCIN (MART.)
MITOMYCIN [MART.]
MITOMYCIN (USP-RS)
MITOMYCIN [USP-RS]
MITOMYCIN C (IARC)
MITOMYCIN C [IARC]
Mitomycin (TN)
1404-00-8
Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methoxy-5-methyl-, carbamate (ester)
Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS,8S,8aR,8bS)-
C15H18N4O5
MITOMYCIN (EP MONOGRAPH)
MITOMYCIN [EP MONOGRAPH]
MITOMYCIN (USP MONOGRAPH)
MITOMYCIN [USP MONOGRAPH]
Mitomycin (USAN:USP:INN:BAN)
CAS-50-07-7
Muamycin (TN)
NSC 26980
((1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl)methyl carbamate
(1aS,8S,8aR,8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione
[(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate
[(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
[1aS-(1aalpha,8beta,8aalpha,8balpha)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione
Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aS,8S,8aR,8bS)-
Mitomycin (USP/INN)
MLS002702984
(amino-methoxy-methyl-dioxo-[?]yl)methyl carbamate
RCRA waste no. U010
7-Amino-9.alpha.-methoxymitosane
Mutamycine
Mitocin
Mitolem
Mitomycine C
Mito-Medac
Mitomycin-X
NCGC00095258-01
((1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino(2',3':3,4)pyrrolo(1,2-a)indol-8-yl)methyl carbamate
(1as,8s,8ar,8bs)-6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione
[(1aS,8S,8aR,8bS)-6-amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate
Mitomycin; [(1aS,8S,8aR,8bS)-6-Amino-8a-methoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2'',3'':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate; Mitomycin C
Jelmyto (TN)
MITO
Mitomycin C from Streptomyces caespitosus
MITOMYCIN [INN]
Mitomycin C (JP18)
MITOMYCIN [HSDB]
MITOMYCIN [USAN]
MITOMYCIN [VANDF]
MITOMYCIN C [MI]
CHEMBL105
MITOMYCIN C [JAN]
MITOMYCIN [WHO-DD]
Mitomycin C - High Purity
SCHEMBL3760
CBiol_001927
BSPBio_001267
KBioGR_000607
KBioSS_000607
Mitomycin C (4% in NaCl)
MLS001332654
Mitozytrex (TN) (Supergene)
50-07-7 (non-salt)
AMETYCIN pound notmitomycin C
GTPL7089
MITOMYCIN [ORANGE BOOK]
KBio2_000607
KBio2_003175
KBio2_005743
KBio3_001073
KBio3_001074
DTXSID00858942
EX-A501
L01DC03
Mitomycin C - Bio-X trade mark
BCPP000410
Bio1_000213
Bio1_000702
Bio1_001191
Bio2_000464
Bio2_000944
HMS1362O09
HMS1792O09
HMS1990O09
HMS2089F16
HMS3403O09
Mutamycin(mitomycin for injection)
AZIRINO(2',3':3,4)PYRROLO(1,2-A)INDOLE-4,7-DIONE, 6-AMINO-8-(((AMINOCARBONYL)OXY)METHYL)-1,1A,2,8,8A,8B-HEXAHYDRO-8A-METHOXY-5-METHYL-, (1AS-(1A.ALPHA.,8.BETA.,8A.ALPHA.,8B.ALPHA.))-
Tox21_111493
AC-918
BDBM50428658
GR-311
HB4458
s8146
AKOS015895703
Tox21_111493_1
AM26019
BCP9000285
CCG-208564
CS-0564
DB00305
KS-5148
7-AMINO-9-ALPHA-METHOXYMITOSANE
IDI1_002219
SMP1_000307
Mitomycin 100 microg/mL in Acetonitrile
NCGC00163468-02
NCGC00163468-03
NCGC00163468-05
NCGC00163468-06
AM161650
BM164668
HY-13316
SMR000058401
BCP0726000181
M2320
NS00004729
C06681
D00208
D91590
AB00918689-03
AB00918689-04
EN300-7405455
BRD-K59670716-001-02-6
BRD-K59670716-001-06-7
Q19856779
WLN: T D3 B556 BN EM JV MVTTT&J GO1 H1OVZ KZ L1
Mitomycin C from Streptomyces caespitosus, >=970 mug/mg (USP XXIV)
Mitomycin C from Streptomyces caespitosus, powder, BioReagent, suitable for cell culture
Mitomycin C from Streptomyces caespitosus, powder, contains NaCl as solubilizer
(1AR)-6-AMINO-8-(((AMINOCARBONYL)OXY)METHYL)-1,1A,2,8,8A,8B-HEXAHYDRO-8A-METHOXY-5-METHYLAZIRINO(2',3':3,4)PYRROLO(1,2-A)INDOLE-4,7-DIONE
(1aS,8S,8aR,8bS)-6-Amino-4,7-dioxo-8a-methoxy-5-methyl-1,1a,2,8,8a,8b-hexahydroazirino(2',3':3,4)pyrrolo(1,2-a)indol-8-ylmethyl carbamate
(1aS-(1a alpha,8beta,8a alpha,8b alpha))-6-amino-8-(((aminocarbonyl)oxy)methyl)-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione
1aS-(1a-a,8b,8a-a,8b-a)-6-Amino-8-(aminocarbonyl)oxymethyl-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino2,'3':3,4pyrrol o1,2-a indole-4,7-dione;MMC;Ametycine
200-008-6
6-AMINO-1,1A,2,8,8A,8B-HEXAHYDRO-8-(HYDROXYMETHYL)-8A-METHOXY-5-METHYLAZIRINO-(2',3':3,4)PYRROLO(1,2-A)INDOLE-4,7-DIONE, CARBAMATE (ESTER)
AZIRINO(2',3':3,4)PYRROLO(1,2-A)INDOLE-4,7-DIONE, 6-AMINO-8-(((AMINOCARBONYL)OXY)METHYL)-1,1A,2,8,8A,8B-HEXAHYDRO-8A-METHOXY-5-METHYL-, (1AS-(1AALPHA,8BETA,8AALPHA,8B.ALPHA)).-
AZIRINO(2',3':3,4)PYRROLO(1,2-A)INDOLE-4,7-DIONE, 6-AMINO-8-(((AMINOCARBONYL)OXY)METHYL)-1,1A,2,8,8A,8B-HEXAHYDRO-8A-METHOXY-5-METHYL-,(1AR-(1AALPHA,8BETA,8AALPHA,8BALPHA))-
Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione,6-amino-8-(((aminocarbonyl)oxy) methyl)-1,1a,2,8,8a,8b-hexahydro-8-a-methoxy-5-methyl-, (1aS-(1aalpha,8beta, 8aalpha,8balpha))-
Azirino[2',4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a- methoxy-5-methyl-, carbamate (ester)
Azirino[2',4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b- hexahydro-8a-methoxy-5-methyl-, [1aR-(1a.alpha.,8.beta.,8a.alpha.,8b.alpha.)]-
Mitomycin C from Streptomyces caespitosus, >=98% (HPLC), potency: >=970 mug per mg (USP XXIV), gamma-irradiated, suitable for cell culture
Solubility of [(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
The solubility of the compound with the formula C43H58N4O12, commonly known for its complex structure, can vary significantly depending on several factors. Here are some important points to consider:
In practice, it is often recommended to conduct solubility tests in varying solvents and temperatures to ascertain the most suitable conditions for this compound. This allows researchers to better understand its behavior in different chemical environments.