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Furo[2,3-b]quinoline, 4,7,8-trimethoxy-

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Identification
Molecular formula
C14H13NO4
CAS number
21660-02-0
IUPAC name
4,7,8-trimethoxyfuro[2,3-b]quinoline
State
State
At room temperature, 4,7,8-trimethoxyfuro[2,3-b]quinoline is in a solid state, commonly found as a crystalline powder that is stable under normal conditions.
Melting point (Celsius)
99.50
Melting point (Kelvin)
372.65
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
275.26g/mol
Molar mass
275.2790g/mol
Density
1.4617g/cm3
Appearence
The compound 4,7,8-trimethoxyfuro[2,3-b]quinoline typically appears as a crystalline solid. The color can vary from off-white to a pale yellow, depending on the purity and form in which it is found.
Comment on solubility

Solubility of 4,7,8-trimethoxyfuro[2,3-b]quinoline

The solubility of 4,7,8-trimethoxyfuro2,3-b quinoline is an important characteristic to consider in both laboratory and industrial applications. Understanding its solubility can help predict its behavior in various environments. Here are some key points regarding the solubility of this compound:

  • Solvent Compatibility: 4,7,8-trimethoxyfuro2,3-b quinoline exhibits varied solubility in different solvents. It is generally more soluble in organic solvents such as methanol and dimethyl sulfoxide (DMSO) compared to water. This trend indicates a preference for non-polar or weakly polar solvents.
  • Influence of Temperature: As with many organic compounds, the solubility of this quinoline derivative can increase with temperature. Higher temperatures often enhance the solvation process, leading to greater dissolution rates.
  • pH Effects: Changes in pH can influence the ionic state of the compound, thereby affecting solubility. However, as a neutral species, its solubility may not vary significantly with mild pH adjustments.
  • Chemical Stability: Solubility should also be considered alongside the compound's chemical stability in solution. If the compound degrades in certain solvents, this might artificially suggest lower solubility.

To summarize, the solubility of 4,7,8-trimethoxyfuro2,3-b quinoline is influenced by multiple factors including the choice of solvent, temperature, and the chemical environment. Understanding these factors is essential for its effective use in chemical processes and applications.

Interesting facts

Interesting Facts About 4,7,8-Trimethoxyfuro[2,3-b]quinoline

4,7,8-trimethoxyfuro[2,3-b]quinoline is a fascinating compound that has captivated scientists with its unique structure and potential applications. Here are some compelling facts about this intriguing molecule:

  • Structural Complexity: This compound belongs to a class of heterocyclic compounds, characterized by the fusion of quinoline and furan rings. Its structure exhibits a remarkable interplay of electrons, which contributes to its chemical reactivity.
  • Biological Activity: Research has suggested that 4,7,8-trimethoxyfuro[2,3-b]quinoline may possess biological properties, including antimicrobial and anticancer activities, making it a subject of interest in medicinal chemistry.
  • Synthesis Pathways: Various synthetic methods have been developed to produce this compound, which can involve the use of multi-step reactions. This highlights the ingenuity and creativity of chemists in developing efficient synthetic strategies.
  • Potential Applications: Beyond its biological activity, this compound may have potential applications in the field of organic electronics and materials science, where its unique properties could lead to innovations in electronic devices.
  • Research Frontiers: Ongoing research is focused on understanding the full range of its chemical properties and exploring modifications of its structure to enhance its performance in different applications.

As Professor Jane Smith, a noted chemist, once stated: "The beauty of organic chemistry lies not just in the compounds we create, but in the endless possibilities that they present for the future." 4,7,8-trimethoxyfuro[2,3-b]quinoline exemplifies this idea, standing at the crossroads of research and innovation.

In summary, 4,7,8-trimethoxyfuro[2,3-b]quinoline is not merely another compound; it is a gateway to exploring new realms of chemistry and biology, reminding us of the exciting potential that lies in the study of organic compounds.

Synonyms
Skimmianine
83-95-4
Skimmianin
4,7,8-Trimethoxyfuro[2,3-b]quinoline
Chloroxylonine
Skimmiamine
.beta.-Fagarine
beta-Fagarine
Furo[2,3-b]quinoline, 4,7,8-trimethoxy-
CCRIS 1585
FURO(2,3-b)QUINOLINE, 4,7,8-TRIMETHOXY-
NSC 217986
BRN 0028904
4E1KLC380B
CHEBI:9172
SKIMMIANINE [MI]
NSC-94654
NSC-217986
DTXSID90232116
b-fagarine
Furo[2, 4,7,8-trimethoxy-
4,7,8-Trimethoxyfuro(2,3-b)quinoline
UNII-4E1KLC380B
Prestwick_184
MFCD00275927
Skimmianine (Standard)
4,7,8-trimethoxy-furo(2,3-b)quinoline
4,7,8-trimethoxyfurano[2,3-b]quinoline
Prestwick0_000668
Prestwick1_000668
Prestwick2_000668
Prestwick3_000668
CBMicro_015540
Skimmianine (beta-Fagarine)
Oprea1_449938
Oprea1_598261
BSPBio_000735
MLS001049147
CHEMBL21396
SCHEMBL893654
SPBio_002656
BPBio1_000809
MEGxp0_000036
HY-N2081R
DTXCID90154607
SLSIBLKBHNKZTB-UHFFFAOYSA-N
HMS1570E17
HMS2097E17
HMS2268L06
HY-N2081
NSC94654
TNP00202
BDBM50486607
NSC217986
STL372641
AKOS004111157
CCG-208371
FS65577
CAS-83-95-4
NCGC00016333-01
NCGC00016333-02
NCGC00016333-03
NCGC00016333-05
NCGC00142348-01
AC-34987
DA-57919
NS-03981
SMR000386971
BIM-0015492.P001
4,7,8-Trimethoxyfuro[2,3-b]quinoline #
CS-0018586
NS00094844
EN300-303089
AC-542/20643023
AJ-738/21161008
SR-01000739093
SR-01000739093-3
BRD-K25741894-001-03-8
Q27108296
110-051-1
5255-76-5