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4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3-one

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Identification
Molecular formula
C6H8N2O2
CAS number
273-83-0
IUPAC name
4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-one
State
State

At room temperature, this compound is typically found as a stable solid. It does not readily react with air or moisture, contributing to its stability in ambient conditions.

Melting point (Celsius)
137.00
Melting point (Kelvin)
410.00
Boiling point (Celsius)
274.00
Boiling point (Kelvin)
547.00
General information
Molecular weight
112.12g/mol
Molar mass
112.1160g/mol
Density
1.2000g/cm3
Appearence

The compound appears as a white to off-white crystalline solid. Its crystalline nature is due to the orderly arrangement of its molecular structure, a characteristic of many organic compounds.

Comment on solubility

Solubility of 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-one

The solubility of 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-one (C6H8N2O2) can significantly influence its application in various chemical processes. Its unique structure contributes to its solubility characteristics, which are primarily determined by the following factors:

  • Polarity: The presence of hydroxyl (–OH) and nitrogen groups enhances its polarity, potentially increasing solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvent molecules can lead to improved solubility in certain environments.
  • Solvent Interactions: The compound is likely to have variable solubility in organic solvents, affected by the solvent's polarity and ability to engage in specific interactions.

However, the precise solubility behavior can vary and is best determined through experimental analysis. As with many organic compounds, factors such as temperature, pH, and the presence of co-solvents may also play crucial roles in the solubility dynamics. Therefore, it is advisable to consult empirical data for practical applications.

Interesting facts

Interesting Facts about 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-one

4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-one is a fascinating compound belonging to the class of heterocycles, characterized by its unique structure, which incorporates both an isoxazole and a pyridine ring. This hybrid structure contributes to its remarkable chemical properties and biological activities. Here are some interesting aspects of this compound:

  • Structural Diversity: The compound features a fused ring system that combines the stability of pyridine with the reactivity of the isoxazole moiety, allowing for a wide range of chemical transformations.
  • Biological Relevance: Compounds like this one have garnered attention due to their potential pharmaceutical applications. Research has shown heterocyclic compounds can act as antibacterial, antifungal, and even antitumor agents.
  • Synthesis Challenges: The synthesis of such compounds can often be complex, requiring multi-step reactions and precise conditions, making their study an intriguing area for chemists.
  • Role in Drug Development: As a part of drug discovery processes, derivatives of this compound can lead to new therapeutic agents, making it a vital subject of investigation in medicinal chemistry.
  • Research Interest: Continued research into the properties and applications of compounds like 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-one is crucial, as they may possess unexpected beneficial effects and activities.

In summary, 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-one stands out not just for its intricate structure but also for its promising potential in the fields of organic chemistry and pharmaceutical sciences. As we continue to explore the diverse world of chemical compounds, the role of such heterocycles remains significant in expanding our understanding and capabilities in drug development.

Synonyms
gaboxadol
THIP
64603-91-4
Gaboxadolum
Gaboxadolum [Latin]
MK-0928
Gaboxadol [USAN:INN]
4,5,6,7-Tetrahydroisoxazolo(5,4-c)pyridin-3-ol
Lu 02-030
4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol
Gaboxadol [INN]
Lu-02-030
4,5,6,7-tetrahydro-[1,2]oxazolo[5,4-c]pyridin-3-one
LU-02030
EINECS 264-963-0
K1M5RVL18S
4,5,6,7-Tetrahydroisoxazolo[5,4-c]pyridin-3(2H)-one
Prestwick-13B03
DTXSID0045206
CHEBI:34373
GABOXADOL [MI]
GABOXADOL [USAN]
NSC-759585
GABOXADOL [WHO-DD]
Isoxazolo(5,4-c)pyridin-3(2H)-one, 4,5,6,7-tetrahydro-
DTXCID8025206
Gaboxadolum (Latin)
MFCD05664626
NSC 759585
NCGC00015982-05
2H,3H,4H,5H,6H,7H-[1,2]oxazolo[5,4-c]pyridin-3-one
Isoxazolo[5,4-c]pyridin-3(2H)-one, 4,5,6,7-tetrahydro-
CAS-64603-91-4
LU 2030
LU-2-030
Gaboxadol (USAN/INN)
UNII-K1M5RVL18S
2H,3H,4H,5H,6H,7H-(1,2)oxazolo(5,4-c)pyridin-3-one
4,5,6,7-TETRAHYDROISOXAZOLO(5,4-C)PYRIDIN-3(2H)-ONE
EI7
4,5,6,7-Tetrahydroisoxazole(5,4-c)pyridin-3-ol
OV-101
ZINC19795995
Spectrum_001484
Tocris-0807
Lopac-T-101
Prestwick0_000972
Prestwick1_000972
Prestwick2_000972
Prestwick3_000972
Spectrum2_001590
Spectrum3_000728
Spectrum4_000172
Spectrum5_001907
Biomol-NT_000235
Lopac0_001233
BSPBio_001003
BSPBio_002256
KBioGR_000683
KBioSS_001964
DivK1c_000211
SPBio_001560
SPBio_002914
BPBio1_000420
BPBio1_001105
CHEMBL312443
GTPL4322
BDBM82002
KBio1_000211
KBio2_001964
KBio2_004532
KBio2_007100
KBio3_001476
NINDS_000211
OV101
BCP07031
NSC_3448
Tox21_110271
BDBM50224809
EX-A11082
MK0928
AKOS006282519
AKOS023612269
Tox21_110271_1
CCG-205307
DB06554
SB18782
SDCCGSBI-0051200.P004
IDI1_000211
NCGC00015982-01
NCGC00015982-02
NCGC00015982-03
NCGC00015982-04
NCGC00015982-06
NCGC00015982-07
NCGC00015982-13
NCGC00024801-01
NCGC00024801-02
NCGC00024801-03
NCGC00263653-01
HY-10232
MS-22812
SY253214
SBI-0051200.P003
CAS_64603-91-4
DB-348908
AB00053777
CS-0002507
NS00035719
D04282
G12553
AB00053777_07
EN300-6233417
4,5,6,7-Tetrahydro-isoxazolo[5,4-c]pyridin-3-ol
4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-one
4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-3-ol
Q4130924
BRD-K89104321-003-14-8
BRD-K89104321-003-15-5
264-963-0