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4,5,6,7-Tetrahydroisoxazolo[4,5-c]pyridin-3-one

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Identification
Molecular formula
C6H8N2O2
CAS number
83846-86-0
IUPAC name
4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-one
State
State

At room temperature, this compound is typically a solid. It is stable under standard conditions of temperature and pressure.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
126.16g/mol
Molar mass
126.1570g/mol
Density
1.3378g/cm3
Appearence

The compound typically appears as a white crystalline solid.

Comment on solubility

Solubility of 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-one (C6H8N2O2)

The solubility of 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-one in various solvents is an intriguing aspect of its chemical behavior. Here are some key points to consider:

  • Polar solvents: This compound is expected to be more soluble in polar solvents due to the presence of hydroxyl (-OH) groups, which can form hydrogen bonds with solvent molecules.
  • Non-polar solvents: Its solubility in non-polar solvents may be limited, as the hydrophobic nature of the pyridine ring might hinder interaction with non-polar media.
  • Water solubility: While specific solubility values in water are not extensively documented, the presence of polar functional groups suggests some degree of water solubility.
  • Temperature impact: As with many organic compounds, increasing the temperature typically enhances solubility, which can be particularly valuable during synthesis or applications.

In summary, while concrete quantitative data can be scarce, the solubility characteristics of 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-one provide insights into its potential uses and storage conditions. Understanding these solubility trends can greatly inform both theoretical and practical applications.

Interesting facts

Interesting Facts about 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-one

4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-one is a fascinating compound that merges the structural elements of isoxazole and pyridine, two important classes in medicinal chemistry. This compound features a unique bicyclic structure, which significantly influences its biological activity and potential medicinal applications.

Key Characteristics

  • Structural Diversity: The incorporation of the isoxazole ring provides distinct electronic properties, which can affect how the compound interacts with biological targets.
  • Pharmacological Relevance: Compounds related to tetrahydroisoxazoles are under investigation for their roles in various therapeutic areas, such as neuroprotection and pain relief.
  • Synthetic Pathways: Organic chemists study various methods to synthesize this compound, with an emphasis on developing efficient and environmentally friendly processes.

This compound represents an intersection of chemistry and drug discovery, and researchers are particularly interested in its potential neuroactive properties. In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." This notion resonates well in the exploration of compounds like 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3-one, where multiple avenues of research may reveal novel therapeutic applications.

Furthermore, compounds such as this are often studied for their role in modulating neurotransmitter systems, which can lead to important insights in developing treatments for conditions like anxiety and depression. Overall, the compound not only exemplifies the beauty of organic chemistry but also highlights the intricate connections between chemical structure and biological function.

Synonyms
THPO
53602-00-9
4,5,6,7-Tetrahydroisoxazolo(4,5-c)pyridin-3-ol
4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridin-3(2H)-one
4,5,6,7-tetrahydro-[1,2]oxazolo[4,5-c]pyridin-3-one
4,5,6,7-Tetrahydroisoxazolo[4,5-c]pyridin-3-ol
CHEMBL150830
2H,3H,4H,5H,6H,7H-[1,2]oxazolo[4,5-c]pyridin-3-one
SCHEMBL455554
GTPL4727
DTXSID90201822
SXXLKZCNJHJYFL-UHFFFAOYSA-N
Isoxazolo(4,5-d)pyridin-3(2H)-one, 4,5,6,7-tetrahydro-
BDBM50226145
AKOS006371191
DA-05117
EN300-306559
Q27088987