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Luteolin

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Identification
Molecular formula
C15H10O6
CAS number
491-70-3
IUPAC name
4,5,6-trihydroxy-2-phenyl-chromen-7-one
State
State

At room temperature, luteolin is typically found as a solid.

Melting point (Celsius)
327.00
Melting point (Kelvin)
600.15
Boiling point (Celsius)
542.05
Boiling point (Kelvin)
815.20
General information
Molecular weight
286.24g/mol
Molar mass
286.2380g/mol
Density
1.6500g/cm3
Appearence

Luteolin is a yellow crystalline compound. It often appears as a fine yellow powder.

Comment on solubility

Solubility of 4,5,6-trihydroxy-2-phenyl-chromen-7-one (C15H10O6)

The solubility of 4,5,6-trihydroxy-2-phenyl-chromen-7-one is a subject of interest due to its unique chemical structure and potential applications. Generally, this compound exhibits certain characteristics that influence its solubility:

  • Polarity: The presence of multiple hydroxy groups can enhance the polarity of the molecule, making it more soluble in polar solvents such as water.
  • Hydrogen Bonding: The hydroxy groups facilitate hydrogen bonding, which often leads to improved solubility in organic solvents.
  • Solvent Interaction: Its solubility can vary significantly between different solvents, meaning that while it might dissolve well in ethanol or methanol, it may have limited solubility in non-polar solvents like hexane.

As a rule of thumb, increased functional groups typically correlate with higher solubility in polar solvents. However, it's crucial to conduct empirical tests to determine the solubility of this specific compound in various conditions. The dynamic interplay of factors contributing to solubility highlights the need for careful consideration when selecting solvents for practical applications.

Interesting facts

Interesting Facts about 4,5,6-Trihydroxy-2-phenyl-chromen-7-one

4,5,6-Trihydroxy-2-phenyl-chromen-7-one, commonly known as a flavonoid compound, is a fascinating member of the chalcone- and flavone-containing family of secondary metabolites. These compounds are notable for their diverse biological activities and potential health benefits.

Biological Significance

This compound has attracted attention due to several important factors:

  • Antioxidant Activity: It exhibits strong antioxidant properties, which help combat oxidative stress and may contribute to preventing various diseases.
  • Anti-inflammatory Effects: Research indicates that it may have the potential to reduce inflammation, making it an interesting candidate for further pharmaceutical applications.
  • Potential Anticancer Properties: Some studies have hinted at its capability to inhibit cancer cell proliferation, particularly in breast and colon cancer cell lines.

Applications and Uses

The applications of this compound can be seen across various fields:

  • Pharmaceuticals: With its promising health benefits, it is being explored for developing new therapeutic agents.
  • Nutraceuticals: Its integration into dietary supplements highlights the growing recognition of natural compounds in health promotion.
  • Cosmetic Industry: Due to its antioxidant properties, it may find applications in formulations aimed at combating skin aging.

Cultural and Historical Context

Historically, many flavonoids have been a part of traditional medicine systems worldwide:

  • In various cultures, plant-based extracts containing similar compounds have long been used for their health benefits.
  • Research into such natural compounds is increasingly validating the traditional use of these plants, bridging the gap between ancient wisdom and modern science.

As we continue to uncover the depths of the functionalities and applications of compounds like 4,5,6-trihydroxy-2-phenyl-chromen-7-one, the significance of their role in both natural and synthetic contexts becomes ever clearer. Whether for their health benefits or their role in medicinal chemistry, these compounds offer a promising avenue for future research and application.