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Tenofovir disoproxil fumarate

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Identification
Molecular formula
C19H30N5O10P
CAS number
202138-50-9
IUPAC name
[(4,5-dihydroxy-1,3-oxazinan-6-yl)methoxy-hydroxy-phosphoryl] [5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate
State
State

At room temperature, Tenofovir disoproxil fumarate is in a solid state, typically in the form of a crystalline powder.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.00
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.00
General information
Molecular weight
519.40g/mol
Molar mass
519.4000g/mol
Density
1.4970g/cm3
Appearence

Tenofovir disoproxil fumarate typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility Characteristics

The solubility of the compound [(4,5-dihydroxy-1,3-oxazinan-6-yl)methoxy-hydroxy-phosphoryl] [5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate, represented by the chemical formula C19H30N5O10P, is influenced by various factors that characterize both its structure and the interactions it may have in solution.

Factors Influencing Solubility

  • Polarity: The hydroxyl (-OH) groups and the phosphate groups in the molecule contribute to its overall polarity, enhancing its ability to dissolve in polar solvents such as water.
  • Hydrogen Bonding: The presence of multiple -OH groups increases the potential for hydrogen bond formation, facilitating interactions with solvent molecules.
  • Functional Groups: The diverse functional groups, including oxazinan and pyrimidin, promote varied solvation behaviors that may enhance or limit solubility depending on the solvent.

It's also important to note that the compound might exhibit different solubility profiles under varying pH conditions due to the acidic and basic characteristics of the functional groups involved. Therefore, understanding its solubility can be summarized as:

  • High solubility: Expected in polar solvents.
  • Moderate solubility: Possible in less polar solvents.

In conclusion, the solubility of this compound is a complex interplay of intermolecular forces and structural attributes. As the solubility can significantly impact the compound's reactivity and stability, careful consideration of the solvent environment is crucial during experimentation.

Interesting facts

Exploring the Unique Compound: [(4,5-dihydroxy-1,3-oxazinan-6-yl)methoxy-hydroxy-phosphoryl] [5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl hydrogen phosphate

This complex chemical compound is intriguing due to its diverse structural components and potential applications. Here are some interesting facts that showcase its significance:

  • Multi-functional Groups: The compound features multiple functional groups, including a phosphoryl moiety and a pyrimidine ring, which can influence its chemical reactivity and biological activity.
  • Role in Biological Systems: Compounds like this one often play crucial roles in biological systems, such as acting as enzyme inhibitors or supporting cellular signaling processes, making them important for drug development and medicinal chemistry.
  • Potential Anti-Cancer Properties: Given its dioxopyrimidine structure, this compound may exhibit anti-cancer properties, mimicking the action of known anti-cancer drugs that target nucleic acids and disrupt cellular processes in cancer cells.
  • Hydroxyl Groups: The presence of multiple hydroxyl groups could enhance hydrogen bonding interactions, possibly leading to improved solubility in polar solvents and better biological activity.

"Chemistry is the magic that brings elements together, revealing new possibilities through compounds like these."

As researchers continue to explore the potential applications of such compounds, the intricate balance of their structural features and functional groups may open doors to novel therapies and materials in future scientific studies.