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Trifluoroacetylacetone

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Identification
Molecular formula
C8H5F3O2
CAS number
367-57-7
IUPAC name
4,4,4-trifluoro-1-(2-thienyl)butane-1,3-dione
State
State

Trifluoroacetylacetone is a liquid at room temperature.

Melting point (Celsius)
-21.00
Melting point (Kelvin)
252.15
Boiling point (Celsius)
124.00
Boiling point (Kelvin)
397.15
General information
Molecular weight
162.12g/mol
Molar mass
162.1230g/mol
Density
1.2689g/cm3
Appearence

Trifluoroacetylacetone is a colorless to yellow liquid. It has the typical appearance of a low viscosity oil.

Comment on solubility

Solubility of 4,4,4-trifluoro-1-(2-thienyl)butane-1,3-dione

The solubility of 4,4,4-trifluoro-1-(2-thienyl)butane-1,3-dione (C8H5F3O2) can be considered through various factors affecting its behavior in different solvents. Here are some key points to note:

  • Polarity: Due to the presence of fluorine atoms and a carbonyl group, this compound exhibits certain polar characteristics, which may enhance its solubility in polar solvents.
  • Solvent Interaction: 4,4,4-trifluoro-1-(2-thienyl)butane-1,3-dione may have limited solubility in non-polar solvents due to the electron-withdrawing nature of the trifluoromethyl group.
  • Common Solvents: It is likely to be soluble in solvents such as:
    • Alcohols (e.g., ethanol, methanol)
    • Aromatic hydrocarbons (e.g., toluene)
    • Acetone
  • Temperature Dependency: As with many organic compounds, an increase in temperature may improve solubility, making it more favorable in thermal applications.

In conclusion, while 4,4,4-trifluoro-1-(2-thienyl)butane-1,3-dione has some polar characteristics, its solubility can vary significantly depending on the solvent used and environmental conditions. Formulating solutions with this compound often requires a careful selection of solvents to optimize its solubility.

Interesting facts

Interesting Facts about 4,4,4-Trifluoro-1-(2-thienyl)butane-1,3-dione

4,4,4-Trifluoro-1-(2-thienyl)butane-1,3-dione is a unique chemical compound that has attracted significant interest in both the fields of organic chemistry and materials science. Here are some compelling points about this fascinating compound:

  • Fluorination Benefits: The presence of trifluoro groups in the molecule greatly influences its reactivity and stability. This fluorination often leads to increased lipophilicity, making such compounds potentially useful in pharmaceuticals.
  • Thienyl Group: The 2-thienyl moiety enhances the compound's electronic properties, which can be advantageous in organic electronic applications, such as organic light-emitting diodes (OLEDs).
  • Biological Activity: Compounds containing diones often exhibit interesting biological activities. Researchers are continually exploring the potential of this class of compounds for therapeutic applications.
  • Research Applications: Studies have indicated that compounds like this one can serve as valuable intermediates in the synthesis of more complex organic molecules, especially in the design of novel agrochemicals.
  • Versatile Building Block: This compound can be used in various synthetic strategies due to its reactive sites. It can participate in different types of reactions, including condensation and cyclization.

In summary, the combination of fluorine and thienyl groups in this compound contributes to its intriguing properties and potential applications, making it a subject of ongoing research in chemistry and materials science. As noted by chemists, "The integration of novel functional groups invariably leads to innovative pathways in molecular design."

Synonyms
2-Thenoyltrifluoroacetone
326-91-0
THENOYLTRIFLUOROACETONE
1,3-Butanedione, 4,4,4-trifluoro-1-(2-thienyl)-
4,4,4-Trifluoro-1-(2-thienyl)-1,3-butanedione
alpha-Thenoyltrifluoroacetone
Perfluoroacetyl(2-thenoyl)methane
4,4,4-trifluoro-1-(thiophen-2-yl)butane-1,3-dione
1-Thenoyl-3,3,3-trifluoroacetone
1,1,1-Trifluoro-3-(2-thenoyl)acetone
4,4,4-Trifluoro-1-(2-thienyl)butane-1,3-dione
1-(2-Thenoyl)-3,3,3-trifluoroacetone
NSC 66544
.alpha.-Thenoyltrifluoroacetone
MYQ9MNW7NI
EINECS 206-316-7
MFCD00005445
4,4,4-trifluoro-1-thiophen-2-ylbutane-1,3-dione
AI3-31295
NSC-66544
4,4,4-TRIFLUORO-1-THIEN-2-YLBUTANE-1,3-DIONE
TTB
CHEMBL1236433
DTXSID1059812
29463-74-9
1,3-Butanedione, 4,4,4-trifluoro-1-(thienyl)- (7CI,8CI,9CI)
TTFA cpd
Trifluorothienylacetone
UNII-MYQ9MNW7NI
2thenoyltrifluoroacetone
2-Theonyltrifluoroacetone
alphaThenoyltrifluoroacetone
SCHEMBL195358
1Thenoyl3,3,3trifluoroacetone
Perfluoroacetyl(2thenoyl)methane
1-Thenoyl-3,3-trifluoroacetone
2-Thenoyltrifluoroacetone, 99%
DTXCID0038542
TXBBUSUXYMIVOS-UHFFFAOYSA-
HMS3604B13
1,1,1Trifluoro3(2thenoyl)acetone
BCP21685
HY-D0190
NSC66544
BBL014250
BDBM50248361
HSCI1_000376
STK020843
1,1-Trifluoro-3-(2-thenoyl)acetone
AKOS000119762
AC-4921
CCG-207997
CS-W020091
DB04795
DS-1137
PS-6790
1, 4,4,4-trifluoro-1-(2-thienyl)-
4,4,4Trifluro1(2thienyl)1,3butanedione
SY004998
DB-001234
1-(Thenoyl-(2'))-3,3,3-trifluoroacetone
EU-0000019
NS00041862
T0438
EN300-18351
F11231
1-(2-thienyl)-4,4,4-trifluoro-1,3-butanedione
2-Thenoyltrifluoroacetone, purum, >=97.0% (GC)
4,4,4-Trifluoro-1-(2-thienyl)-1,3-Butanedion
SR-01000388942
Q5933755
SR-01000388942-1
BRD-K00959089-001-01-4
Z57201518
F0346-3664
2-Thenoyltrifluoroacetone pound>>4,4,4-trifluoro-1-(thiophen-2-yl)butane-1,3-dione
2-Thenoyltrifluoroacetone, for spectrophotometric det. of metal ions, >=99.0%
InChI=1/C8H5F3O2S/c9-8(10,11)7(13)4-5(12)6-2-1-3-14-6/h1-3H,4H2