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4,4-dimethyltetrahydrofuran-2,3-dione

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Identification
Molecular formula
C6H8O3
CAS number
6407-41-6
IUPAC name
4,4-dimethyltetrahydrofuran-2,3-dione
State
State

At room temperature, 4,4-dimethyltetrahydrofuran-2,3-dione is a solid.

Melting point (Celsius)
36.00
Melting point (Kelvin)
309.00
Boiling point (Celsius)
244.00
Boiling point (Kelvin)
517.00
General information
Molecular weight
128.13g/mol
Molar mass
128.1280g/mol
Density
1.0440g/cm3
Appearence

The compound is typically a colorless to yellowish liquid. It may darken upon exposure to light and air over time.

Comment on solubility

Solubility of 4,4-Dimethyltetrahydrofuran-2,3-dione (C6H8O3)

The solubility of 4,4-dimethyltetrahydrofuran-2,3-dione in various solvents is a key factor in its practical applications. Understanding its solubility helps to predict its behavior in different chemical environments. Here are some insights into its solubility characteristics:

  • Polar Solvents: This compound shows a good degree of solubility in polar solvents such as water and methanol. The presence of carbonyl and hydroxyl functional groups enhances its interaction with polar molecules.
  • Non-Polar Solvents: In contrast, the solubility in non-polar solvents is significantly lower. This is primarily due to the lack of strong interactions with non-polar molecules.
  • Concentration Effects: It is observed that solubility can increase with temperature, suggesting a temperature-dependent solubility profile.
  • Applications: The solubility behavior makes it useful in synthesizing various organic compounds, as it can easily dissolve in common laboratory solvents.

Overall, the solubility of 4,4-dimethyltetrahydrofuran-2,3-dione in polar solvents plays a crucial role in its functionality and application in organic chemistry.

Interesting facts

Interesting Facts about 4,4-Dimethyltetrahydrofuran-2,3-dione

4,4-Dimethyltetrahydrofuran-2,3-dione is a fascinating compound that attracts the attention of chemists due to its unique structural features and versatile applications. Here are some compelling insights:

  • Synthetic Utility: This compound is often utilized as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals, showcasing its importance in medicinal chemistry.
  • Reactivity: The presence of two carbonyl groups in its structure makes this compound reactive and valuable in many organic reactions, such as aldol condensations and Michael additions.
  • Cyclic Structure: Its cyclic nature contributes to its stability and reactivity profile, which can be exploited in creating more complex structures, making it a favorite among synthetic chemists.
  • Biological Relevance: Some derivatives of 4,4-dimethyltetrahydrofuran-2,3-dione have shown interesting biological activities, which piques the interest of researchers exploring new therapeutic agents.
  • Research Context: The compound has been the subject of numerous studies aimed at understanding its behavior under different conditions, expanding our knowledge in the fields of organic and medicinal chemistry.
  • Environmental Impact: As a compound used in chemical manufacturing, there is a growing interest in understanding how its synthesis and degradation products interact with natural systems, emphasizing the importance of environmentally-focused chemistry.

In conclusion, 4,4-dimethyltetrahydrofuran-2,3-dione represents a compelling example of a compound where structural intricacies translate into a wide range of applications, illustrating the close relationship between chemical structure and function.

Synonyms
13031-04-4
4,4-Dimethyldihydrofuran-2,3-dione
Dihydro-4,4-dimethyl-2,3-Furandione
Keto-pantoyllactone
ketopantolactone
2-dehydropantolactone
4,4-dimethyloxolane-2,3-dione
2,3-Furandione, dihydro-4,4-dimethyl-
4,4-Dimethyldihydro-2,3-furandione
Dihydro-4,4-dimethylfuran-2,3-dione
2-dehydropantoyl lactone
ketopantoyl lactone
EINECS 235-891-7
MFCD00012331
4,4-dimethyl-4,5-dihydrofuran-2,3-dione
DTXSID30156448
2-oxopantoyl lactone
SCHEMBL538500
LCZC2502
DTXCID7078939
CHEBI:18395
HRTOQFBQOFIFEE-UHFFFAOYSA-
NAA03104
AKOS015905266
2-Oxo-3,3-dimethyl-gamma-butyrolactone
4,4-Dimethyldihydro-2,3-furandione #
4,4-dimethyl-tetrahydro-furan-2,3-dione
DS-15458
SY251591
DB-041958
CS-0065829
Dihydro-4,4-dimethyl-2,3-furandione, 97%
NS00024096
C01125
C72205
EN300-116454
Q27103050
InChI=1/C6H8O3/c1-6(2)3-9-5(8)4(6)7/h3H2,1-2H3
235-891-7