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4-Ureidoimidazole-5-carboxylic acid

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Identification
Molecular formula
C5H6N4O3
CAS number
79965-15-0
IUPAC name
4-ureido-1H-imidazole-5-carboxylic acid
State
State
At room temperature, 4-ureidoimidazole-5-carboxylic acid is found as a solid. It is stable under standard conditions of temperature and pressure.
Melting point (Celsius)
235.00
Melting point (Kelvin)
508.15
Boiling point (Celsius)
385.00
Boiling point (Kelvin)
658.15
General information
Molecular weight
185.15g/mol
Molar mass
185.1530g/mol
Density
1.5600g/cm3
Appearence

4-Ureidoimidazole-5-carboxylic acid typically appears as a crystalline solid. Its color can vary from white to a slightly off-white depending on purity and sample variation.

Comment on solubility

Solubility of 4-ureido-1H-imidazole-5-carboxylic acid

The solubility of 4-ureido-1H-imidazole-5-carboxylic acid (C5H6N4O3) is influenced by several factors, particularly its functional groups and molecular structure.

This compound exhibits considerable solubility in polar solvents such as water due to the presence of:

  • Carboxylic acid group: Facilitates hydrogen bonding with water molecules.
  • Ureido group: Provides additional sites for interactions, enhancing solubility.

Moreover, the imidazole ring contributes to its amphipathic nature, making it:

  • More soluble in aqueous environments, allowing it to participate in biochemical processes.
  • Less soluble in non-polar solvents, where interaction is limited to hydrophobic effects.

In summary, the solubility of 4-ureido-1H-imidazole-5-carboxylic acid is characterized by:

  • High aqueous solubility due to polar functional groups.
  • Low solubility in non-polar solvents due to its polar nature.

This intricate balance of polarity plays a crucial role in its usability in various chemical and biological applications.

Interesting facts

Interesting Facts about 4-Ureido-1H-Imidazole-5-Carboxylic Acid

4-Ureido-1H-imidazole-5-carboxylic acid, often referred to in scientific literature as a derivative of imidazole, is a fascinating compound with various biochemical implications. Here are some key points that highlight the importance and applications of this compound:

  • Biological Significance: This compound plays a role in the synthesis of purines and nucleotides, making it important in cellular metabolism.
  • Pharmaceutical Applications: Research suggests that derivatives of 4-ureido-1H-imidazole-5-carboxylic acid may have potential therapeutic effects, particularly in anti-inflammatory and anti-cancer treatments.
  • Catalytic Properties: Its structure allows it to act as a catalyst in various biochemical reactions, which can be crucial in organic synthesis and industrial applications.
  • Research Utility: 4-Ureido-1H-imidazole-5-carboxylic acid is utilized in laboratories for the synthesis of more complex molecules, making it an important building block in medicinal chemistry.

As scientists continue to explore its properties, 4-ureido-1H-imidazole-5-carboxylic acid is proving to be a compound of great interest. By studying its interactions and transformations, we can further understand how nitrogen-containing compounds influence biological systems and pave the way for innovative therapeutic strategies.

Interestingly, the related imidazole ring structure is common in many biologically active molecules, emphasizing the significance of this compound within the broader landscape of chemistries. As researchers delve deeper into the chemistry of such compounds, the potential for new discoveries seems limitless.

Synonyms
5-ureidoimidazole-4-carboxylic acid
5-Ureido-4-imidazole carboxylate
4-Ureido-5-imidazolecarboxylic acid
4-(carbamoylamino)-1H-imidazole-5-carboxylic acid
5-(carbamoylamino)-1H-imidazole-4-carboxylic acid
NoName_136
C05515
SCHEMBL1332446
CHEBI:27580
DTXSID20901080
4-Imidazolecarboxylic acid, 5-ureido-
4919-06-6
Q27103207