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4-Quinolyl-(5-vinylquinuclidin-2-yl)methanol

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Identification
Molecular formula
C18H23NO
CAS number
100403-19-8
IUPAC name
4-quinolyl-(5-vinylquinuclidin-2-yl)methanol
State
State

At room temperature, 4-Quinolyl-(5-vinylquinuclidin-2-yl)methanol is typically in a solid state. It is often used in its crystalline form.

Melting point (Celsius)
53.40
Melting point (Kelvin)
326.60
Boiling point (Celsius)
312.50
Boiling point (Kelvin)
585.60
General information
Molecular weight
285.38g/mol
Molar mass
285.3780g/mol
Density
0.9826g/cm3
Appearence

The compound generally appears as a colorless to pale yellow liquid. It may have a characteristic odor depending on its purity and specific formulation.

Comment on solubility

Solubility of 4-quinolyl-(5-vinylquinuclidin-2-yl)methanol

Understanding the solubility of 4-quinolyl-(5-vinylquinuclidin-2-yl)methanol (C18H23NO) is essential for its application in various chemical processes. The solubility of organic compounds like this one is influenced by their molecular structure and nature. Here are a few key points to consider:

  • Polarity: With the presence of both a hydroxyl group (-OH) and a quinuclidin-2-yl moiety, this compound exhibits a degree of polarity that can enhance its solubility in polar solvents such as water.
  • Solvent Interaction: It is expected to show better solubility in alcohols and ethers due to the compatibility of hydroxyl groups and the overall structure with these solvents.
  • Hydrophobic Effects: The presence of the quinuclidine structure could introduce hydrophobic characteristics, potentially reducing solubility in highly polar solvents but enhancing solubility in organic solvents.

In summary, the solubility of 4-quinolyl-(5-vinylquinuclidin-2-yl)methanol is likely to be moderate in polar solvents while exhibiting increased solubility in organic solvents. It is crucial to conduct experimental solubility studies to determine exact values and behaviors in various environments.

Interesting facts

Interesting Facts about 4-quinolyl-(5-vinylquinuclidin-2-yl)methanol

4-quinolyl-(5-vinylquinuclidin-2-yl)methanol is a fascinating chemical compound that is of great interest in the field of medicinal chemistry. Here are some remarkable aspects of this compound:

  • Structural Diversity: The presence of both quinoline and quinuclidine motifs in its structure contributes to its unique properties. Quinoline derivatives are often known for their biological activity, whereas quinuclidine derivatives are associated with various physiological effects.
  • Potential Biological Activity: Compounds that incorporate quinuclidine structures have been studied for their potential as antidepressants, analgesics, and antitumor agents. This suggests that 4-quinolyl-(5-vinylquinuclidin-2-yl)methanol could have intriguing pharmacological potentials worth exploring.
  • Synthetic Routes: The synthesis of this compound can involve advanced reaction techniques, making it a valuable target for synthetic organic chemists. Understanding the different ways to construct this complex molecule can enhance the skills of budding chemists.
  • Research Applications: Due to its structural attributes, this compound could serve as a crucial building block in the synthesis of more complex pharmaceutical agents. It opens avenues for exploring new drugs aimed at various neurological disorders.
  • Stability and Reactivity: Like many compounds with a quinuclidine and quinoline framework, its stability and reactivity can be influenced by functional groups that can be modified or replaced, allowing for viable derivatives with different properties.

As the field of medicinal chemistry continues to evolve, compounds such as 4-quinolyl-(5-vinylquinuclidin-2-yl)methanol may play key roles in the crafting of novel therapeutics that can significantly impact healthcare outcomes.

Synonyms
Cinchonan-9-ol
118-10-5
Cinchovatine
alpha-Quinidine
quinolin-4-yl(5-vinylquinuclidin-2-yl)methanol
GNF-PF-5411
9-epi-Cinchonidine
L-Cinchonidine
MLS002637808
1071759-34-6
NSC5364
.alpha.-Quinidine
{5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl}(quinolin-4-yl)methanol
4-QUINOLYL(5-VINYL-1-AZABICYCLO[2.2.2]OCT-2-YL)METHANOL
nchem.180-comp1b
SMR001488502
NSC6176
(8.alpha.,9R)-Cinchonan-9-ol
a-quinidine
(8a,9R)-Cinchonan-9-ol, 9CI
alpha -quinidine
Cinchonan-9-ol,9R)-
MLS006011421
CHEMBL15134
SCHEMBL732494
(+)-Cinchonine; D-Cinchonine
(8alpha ,9R)-Cinchonan-9-ol
CHEBI:183479
Cinchonan-9-ol, (8alpha 9R)-
HMS3369H22
HMS3372L22
AAA48570
AAA55054
BCP18343
Cinchonan-9-ol, (8alpha ,9R)-
(5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl)-quinolin-4-ylmethanol
BBL012269
STL163586
AKOS000118852
AKOS022060412
CCG-245136
SB40649
NCGC00094864-01
NCGC00094864-02
NCGC00094864-03
NCGC00094864-04
SY010860
SY011344
VS-03255
DB-041389
CS-0267207
NS00010165
NS00076878
EN300-19538
AB00973495-02
WLN: T66 BNJ EYQ- DT66 A B CNTJ A1U1
F0001-1271
Z104474148
alpha-Quinidine; (8alpha,9R)-Cinchonan-9-ol; (8alpha,9R)-Cinchonan-9-ol; alpha-Quinidine