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Pyrovalerone

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Identification
Molecular formula
C16H23NO3
CAS number
3563-49-3
IUPAC name
4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one
State
State

At room temperature, pyrovalerone is found in a solid state, typically as a crystalline powder.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.15
Boiling point (Celsius)
393.50
Boiling point (Kelvin)
666.65
General information
Molecular weight
305.42g/mol
Molar mass
305.4210g/mol
Density
1.0770g/cm3
Appearence

Pyrovalerone typically appears as a white crystalline solid. It may be odorless and is often synthesized for various research purposes.

Comment on solubility

Solubility of 4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one (C16H23NO3)

The solubility of 4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one can be influenced by several factors. Although the exact solubility values can vary based on the solvent and conditions, some key points include:

  • Polarity: Given the presence of both a pyrrolidine ring and multiple methoxy groups, this compound exhibits moderate polarity, which can enhance its solubility in polar solvents.
  • Solvent Compatibility: It is likely to be soluble in organic solvents such as:
    • Dimethyl sulfoxide (DMSO)
    • Methanol
    • Ethyl acetate
  • Water Solubility: Due to the presence of hydrophobic groups (the trimethoxyphenyl part), solubility in water may be limited, indicating that it is more likely to dissolve in non-aqueous solutions.
  • Temperature Influence: As with many organic compounds, increased temperature can enhance solubility, allowing more of the compound to dissolve in given solvents.

In conclusion, while 4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one demonstrates moderate solubility characteristics, particularly in polar organic solvents, its behavior in aqueous solutions may not be as favorable. Understanding these solubility parameters is crucial for applications in synthesis and formulation.

Interesting facts

Interesting Facts about 4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one

4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one, often categorized within a specific class of compounds, is renowned for its intriguing structure and potential applications. Here are some fascinating aspects of this compound:

  • Chemical Structure: The compound features a distinctive pyrrolidine ring, which plays a crucial role in its pharmacological properties. This structure contributes to its ability to interact with various biological systems.
  • Potential Uses: Research suggests that compounds with similar structures may have implications in fields such as medicinal chemistry and drug design. They could potentially serve as leads for developing new therapeutic agents.
  • Substituent Significance: The presence of the 2,4,6-trimethoxyphenyl group is significant as it enhances the compound's lipophilicity, which may affect its absorption and activity in biological systems. This moiety is commonly associated with various biological activities.
  • Research Focus: Ongoing studies on compounds related to 4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one highlight its potential role in treating conditions such as anxiety and depression.

The study of this compound is notable not just for its chemical properties but also for the insights it provides into the intricate relationships between molecular structure and biological activity. As a chemical scientist or a chemistry student, delving into the mechanisms and applications of such compounds can reveal the nuanced ways in which chemistry intersects with health and disease.

Synonyms
Buflomedil
55837-25-7
Buflomedilum
Buflomedilum [INN-Latin]
1-Butanone, 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-
Buflomedil [INN:BAN:DCF]
4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone
EINECS 259-851-3
Buflomedil (INN)
Bufedil
Lofton
UNII-V7I71DQ432
2',4',6'-Trimethoxy-4-(1-pyrrolidinyl)butyrophenone
V7I71DQ432
BUFLOMEDIL [MI]
BUFLOMEDIL [INN]
4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one
BUFLOMEDIL [WHO-DD]
CHEMBL188921
DTXSID5022697
LL 1656
blufomedil
bufomedil
4-(pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one
Buflomedilum (INN-Latin)
Buflohexal
Sinoxis
Buflo-Puren
Buflomedil Lindo
Buflomedil Stada
buflomedil von ct
Buflo AbZ
Buflomedil Heumann
Buflo 1A Pharma
Buflo-POS
Buflomedil-ratiopharm
NCGC00016831-01
CAS-35543-24-9
Prestwick0_000426
Prestwick1_000426
Prestwick2_000426
Prestwick3_000426
BSPBio_000412
SCHEMBL150905
SPBio_002351
BPBio1_000454
DTXCID902697
CHEBI:94538
HY-B0484A
C04AX20
BDBM50170664
AKOS015967520
DB13510
NCGC00016831-02
NCGC00016831-04
NCGC00164382-01
AC-11046
DA-71806
SBI-0207020.P001
CS-0013450
NS00000498
D07176
E79447
Q417862
BRD-K19462402-003-03-0
BRD-K19462402-003-13-9
BRD-K19462402-003-23-8
BRD-K19462402-003-24-6
4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone #
4-Pyrrolidin-1-yl-1-(2,4,6-trimethoxy-phenyl)-butan-1-one
4-pyrrolidin-1-yl-1-[2,4,6-tris(methyloxy)phenyl]butan-1-one
259-851-3