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4-Oxo-4-(3-pyridyl)butanoic acid

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Identification
Molecular formula
C9H9NO3
CAS number
6315-52-8
IUPAC name
4-oxo-4-(3-pyridyl)butanoic acid
State
State

At room temperature, 4-Oxo-4-(3-pyridyl)butanoic acid exists as a solid. It is relatively stable under normal conditions and should be handled with care to prevent decomposition or reaction with moisture in the air.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.00
Boiling point (Celsius)
378.00
Boiling point (Kelvin)
651.00
General information
Molecular weight
179.18g/mol
Molar mass
179.1840g/mol
Density
1.3567g/cm3
Appearence

4-Oxo-4-(3-pyridyl)butanoic acid typically appears as an off-white or pale yellow powder. It is a crystalline solid that may be slightly hygroscopic. The compound can have a slight odor that is characteristic of pyridine derivatives.

Comment on solubility

Solubility of 4-oxo-4-(3-pyridyl)butanoic acid

4-Oxo-4-(3-pyridyl)butanoic acid, with the chemical formula C9H9NO3, showcases interesting solubility characteristics that are influenced by its functional groups and molecular structure.

General Solubility Profile

This compound is likely to be moderately soluble in water due to the presence of the carboxylic acid group, which can engage in hydrogen bonding with water molecules. However, the aromatic pyridine ring might slightly hinder solubility due to its hydrophobic nature. Key factors affecting the solubility include:

  • Hydrogen Bonding: The carboxylic group can form hydrogen bonds with water, enhancing solubility.
  • Hydrophilic vs. Hydrophobic Balance: The presence of the pyridine ring introduces a degree of hydrophobic character, which may pose limitations on solubility.
  • pH Sensitivity: As a weak acid, the solubility might increase in basic conditions where the compound is deprotonated.

Practical Implications

The solubility of 4-oxo-4-(3-pyridyl)butanoic acid is essential for its potential applications in pharmaceuticals and organic synthesis. For instance:

  • The higher solubility in slightly basic solutions may be exploited in drug formulations.
  • Solubility Studies: Understanding this compound’s solubility is crucial in predicting its behavior in biological systems.

In conclusion, while 4-oxo-4-(3-pyridyl)butanoic acid can be reasonably expected to be soluble in water, the overall solubility properties are determined by a delicate balance of its hydrophilic and hydrophobic features.

Interesting facts

Interesting Facts about 4-oxo-4-(3-pyridyl)butanoic Acid

4-oxo-4-(3-pyridyl)butanoic acid is a fascinating compound that has garnered attention in both academic and applied chemistry fields. Here are some compelling aspects of this compound:

  • Biological Significance: This compound is part of a broader class of molecules that show potential for various biological activities. The presence of the pyridine ring suggests that it may interact with biological systems, making it a candidate for pharmacological studies.
  • Synthesis Potential: The synthetic pathways leading to 4-oxo-4-(3-pyridyl)butanoic acid involve several interesting chemical reactions. Understanding its synthesis can illuminate techniques in organic chemistry, particularly in creating heterocycles and functionalized acids.
  • Applications in Drug Design: Due to its structural features, this compound may serve as a scaffold for designing new therapeutic agents. The incorporation of the pyridine moiety enhances lipophilicity and can improve binding interactions with biological targets.
  • Research Interest: Ongoing research focuses on the derivatives of compounds similar to 4-oxo-4-(3-pyridyl)butanoic acid, exploring their potential as anti-inflammatory, antimicrobial, or anticancer agents.
  • Analytical Chemistry: This compound can be analyzed using various spectroscopic methods, such as NMR and Mass Spectrometry, which provides insights into its structure and helps confirm its molecular identity.

Overall, 4-oxo-4-(3-pyridyl)butanoic acid is a prime example of how seemingly simple organic compounds can play critical roles in scientific research and application. Its unique structure fuels interest in both its theoretical and practical implications, making it an exciting topic for students and professionals alike.

Synonyms
4192-31-8
4-oxo-4-(pyridin-3-yl)butanoic acid
3-succinoylpyridine
4-Oxo-4-pyridin-3-yl-butyric acid
4-Oxo-4-(3-pyridyl)butyric acid
4-oxo-4-(3-pyridyl)butanoic acid
4-oxo-4-pyridin-3-ylbutanoic acid
gamma-oxo-3-pyridinebutyric acid
gamma-oxo-3-pyridinebutanoic acid
1-(3-pyridyl)-1-butanone-4-carboxylic acid
3-pyridinebutanoic acid, gamma-oxo-
8Y4EX5XJ5B
CHEBI:66951
4-oxo-4-(3-pyridyl)-butanoic acid
g-oxo-3-pyridinebutyric acid
gamma-oxo-3-pyridinebutanoate
4-(PYRID-3-YL)-4-OXO-BUTYRIC ACID HYDROCHLORIDE
DTXSID60863335
4-oxo-4-(3-pyridyl)-butyric acid
gamma-Oxo-3-pyridinebutyric Acid, N-Hydroxysuccinimide Ester
.GAMMA.-OXO-3-PYRIDINEBUTANOIC ACID
3-PYRIDINEBUTANOIC ACID, .GAMMA.-OXO-
.GAMMA.-3-PYRIDYL-.GAMMA.-OXOBUTYRIC ACID
4-oxo-4-(3-pyridyl)-butanoate
MFCD00870737
OPBA
g-oxo-3-Pyridinebutyrate
g-oxo-3-Pyridinebutanoate
UNII-8Y4EX5XJ5B
gamma-oxo-3-Pyridinebutyrate
g-oxo-3-Pyridinebutanoic acid
SCHEMBL2638149
CHEMBL3544790
4-oxo-4-(3-Pyridyl)-butyrate
DTXCID30811969
JGSUNMCABQUBOY-UHFFFAOYSA-N
4-oxo-4-(Pyridin-3-yl)butyrate
HMS1701M19
Discontinued. Please see O859160
STK689348
4-oxo-4-(3-pyridinyl)butanoic acid
4-oxo-4-(pyridin-3-yl)butanoicacid
4-oxo-4-(pyridin-3-yl)butyric acid
AKOS000300287
FO26681
SB37120
NCGC00338261-01
AS-10189
CS-0233523
GAMMA-3-PYRIDYL-GAMMA-OXOBUTYRIC ACID
NS00014734
4-Oxo-4-(3-pyridyl)-butanoic acid (OPBA)
C19569
EN300-134219
G41894
AB01331602-02
AE-641/00775044
Q27135538
Z838955798
?-Oxo-3-pyridinebutanoic acid;3-Succinoylpyridine;4-(3-Pyridyl)-4-oxobutyric acid
675-338-0