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4-Nitroindenone

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Identification
Molecular formula
C9H5NO3
CAS number
3665-98-5
IUPAC name
4-nitroinden-1-one
State
State
The compound is typically in a solid state at room temperature. It remains stable in this form but requires special handling due to its nitro group, which can present a hazard in terms of reactivity.
Melting point (Celsius)
101.00
Melting point (Kelvin)
374.00
Boiling point (Celsius)
299.00
Boiling point (Kelvin)
572.00
General information
Molecular weight
175.14g/mol
Molar mass
175.1560g/mol
Density
1.3450g/cm3
Appearence

4-Nitroindenone typically appears as a pale yellow solid. This compound consists of a fused ring structure due to the indene and ketone units, with a nitro group attached at the fourth position. It may appear crystalline under certain conditions, depending on purity and the exact method of synthesis.

Comment on solubility

Solubility of 4-nitroinden-1-one (C9H5NO3)

4-nitroinden-1-one is a compound of interest due to its unique structure and properties. When it comes to solubility, several factors play a crucial role:

  • Polarity: The presence of the nitro group (-NO2) introduces some polarity to the molecule. However, the overall structure remains predominantly hydrophobic due to the fused ring systems.
  • Solvent Compatibility: This compound generally shows good solubility in organic solvents such as ethanol, acetone, and chloroform, making it favorable for various chemical reactions and applications.
  • Water Solubility: In contrast, 4-nitroinden-1-one has limited solubility in water. This is typical for many organic compounds containing large non-polar hydrocarbon portions.

As a rule of thumb, one can state that:

“Like dissolves like”

This means that non-polar solvents are more effective in dissolving compounds that possess similar non-polar characteristics. Therefore, to work effectively with 4-nitroinden-1-one, it is important to choose appropriate organic solvents where it is known to dissolve.

Interesting facts

Exciting Insights into 4-Nitroinden-1-one

4-Nitroinden-1-one is a fascinating compound with intriguing properties and applications, making it a topic of interest among organic chemists. Here are some interesting facts about this compound:

  • Structure and Stability: The compound features a fused ring system that greatly contributes to its stability. The nitro group (\−NO2) is positioned at the 4-position, which can influence the compound's reactivity and overall characteristics.
  • Diverse Applications: 4-Nitroinden-1-one is not just a chemical name; it serves as an important intermediate in organic synthesis. It's used in the development of dyes, pharmaceuticals, and agrochemicals.
  • Biological Activity: Research has shown that derivatives of 4-nitroinden-1-one exhibit interesting biological properties, including potential antimicrobial and anticancer activities. This has led to investigations into its pharmacological potentials.
  • Synthetic Pathways: The synthesis of 4-nitroinden-1-one can involve several methods, including the nitration of indan-1-one, which highlights its importance in demonstrating reaction mechanisms and methodologies in organic chemistry labs.
  • Further Research: As a compound that has yet to be fully explored, it provides numerous opportunities for research, particularly in the fields of medicinal chemistry and materials science.

In conclusion, 4-nitroinden-1-one is a compound that bridges chemistry with practical applications, illustrating the beauty and utility of organic molecules in various fields. With its varied properties and continuing research interests, it remains a valuable compound for scientific exploration.

Synonyms
4-nitro-inden-1-one
4-nitroinden-1-one
16369-04-3
4-nitro-1H-inden-1-one
SCHEMBL4321464
DB04479
PD006653
NS00069471
Q27095254