Interesting facts
Interesting Facts about 4-methyl-N-phenyl-benzenesulfonamide
4-methyl-N-phenyl-benzenesulfonamide, also known as a sulfonamide compound, occupies an important place in the realm of medicinal chemistry. Here are some intriguing aspects of this compound:
- Medicinal Applications: Sulfonamide compounds, including 4-methyl-N-phenyl-benzenesulfonamide, have been widely utilized in the field of pharmaceuticals, primarily as antibacterial agents. They inhibit bacterial growth by interfering with the synthesis of folate, a vital nutrient.
- Structure-Activity Relationship: The unique structure of 4-methyl-N-phenyl-benzenesulfonamide allows for varying biological activities based on modifications to its structure, which makes it a subject of interest for further drug development.
- Drug Discovery: With the rise of antibiotic resistance, compounds like this one are being revisited in drug discovery programs. The exploration of their derivatives could lead to the development of new therapeutic agents.
- Synergistic Effects: Combining 4-methyl-N-phenyl-benzenesulfonamide with other drugs may produce synergistic effects, enhancing efficacy while potentially reducing toxicity.
- Research Opportunities: Ongoing research continues to discover additional properties and potential applications for sulfonamides like this compound, including anti-inflammatory and antitumor activities.
As you delve deeper into the world of sulfonamide compounds, remember the words of renowned chemist Linus Pauling: "The best way to have a good idea is to have a lot of ideas." Exploring the diverse functionalities of compounds such as 4-methyl-N-phenyl-benzenesulfonamide may unveil novel treatments and insights.
Synonyms
p-TOLUENESULFONANILIDE
68-34-8
4-Methyl-N-phenylbenzenesulfonamide
N-Tosylaniline
Benzenesulfonamide, 4-methyl-N-phenyl-
Tosylaniline
N-Phenyl-p-toluenesulfonamide
p-Toluenesulfonylanilide
p-Toluenesulfanilide
4-methyl-N-phenylbenzene-1-sulfonamide
[(4-methylphenyl)sulfonyl]phenylamine
N(1)-Phenyl-4-toluenesulfonamide
CHEMBL182659
DTXSID40883218
NSC-2178
4-Methyl-N-phenyl-benzenesulfonamide
N-Tosylbenzenamine
NSC2178
Topcizer 108
MFCD00025989
p-toluene sulfonanilide
N-p-Toluenesulfonylaniline
4-Methylbenzenesulfonanilide
SCHEMBL322990
N1-Phenyl-4-toluenesulfonamide
U2P2PZ5R29
N-(Phenyl) p-toluenesulfonamide
DTXCID501022767
GLXC-04993
N-Phenyl-4-methylbenzenesulfonamide
AAA06834
NSC24629
BDBM50428400
N-[(4-Methylphenyl)sulfonyl]aniline
NSC-24629
STK059716
AKOS001073541
AS-62180
DB-055139
CS-0132035
NS00041324
T0282
EN300-15972
D70395
AE-848/00888030
Z45619486
Solubility of 4-methyl-N-phenyl-benzenesulfonamide
4-methyl-N-phenyl-benzenesulfonamide (C13H13NO2S) exhibits intriguing solubility characteristics. This compound is known to be:
The presence of the sulfonamide functional group contributes significantly to its solubility profile. As noted by chemists, "the polarity introduced by sulfonamide groups can enhance dissolution in aqueous environments." Here are some important factors affecting its solubility:
In summary, 4-methyl-N-phenyl-benzenesulfonamide exhibits polar character, making it more suitable for dissolution in polar solvents while displaying limited solubility in non-polar solvents. These properties are crucial for various applications in pharmaceuticals and organic synthesis.