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Tetrabenazine

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Identification
Molecular formula
C19H27NO3
CAS number
58-46-8
IUPAC name
4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene
State
State

At room temperature, tetrabenazine is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
334.30
Boiling point (Kelvin)
607.50
General information
Molecular weight
317.44g/mol
Molar mass
317.4380g/mol
Density
1.2000g/cm3
Appearence

Tetrabenazine is a white to off-white crystalline powder. It is typically supplied in its pure form and is known for its stability under normal conditions.

Comment on solubility

Solubility of 4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene

The solubility of 4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene (C19H273) is a subject of interest due to its complex molecular structure. Understanding its solubility can help in deducing its potential applications in various fields. Here are some key points about its solubility:

  • Polar and Non-Polar Solvents: The presence of the methoxy group (-OCH3) suggests that the compound may exhibit higher solubility in polar solvents compared to non-polar solvents. However, the overall hydrophobic character contributed by the tetracyclic structure could limit solubility.
  • Hydrogen Bonding: The potential for hydrogen bonding with water molecules may enhance solubility to some extent, but the large hydrocarbon framework might counteract this effect.
  • Practical Applications: Knowing the solubility is crucial for pharmaceutical formulations where poor solubility might affect bioavailability.

In conclusion, while the solubility profile of C19H27NO3 may not be straightforward, it will likely be influenced by the balance of polar and non-polar characteristics. Careful experimentation is necessary to determine its solubility in various solvents to optimize its usage.

Interesting facts

Interesting Facts about 4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene

4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene, a complex organic compound, displays a fascinating structural variety that is notable in organic and medicinal chemistry. Here are some engaging aspects:

  • Unique Structure: This compound features a tetracyclic core, which is a configuration that can be seen in many natural products, especially within the field of alkaloids. Its unique rings provide it with various potential interactions in biochemical systems.
  • Biological Importance: Compounds with similar structures often exhibit significant biological activity, including antimicrobial and anticancer properties. Researchers are investigating how this compound can contribute to the development of new pharmaceuticals.
  • Synthesis Strategies: The synthesis of such complex compounds often involves multiple steps, showcasing the ingenuity of chemists. Techniques like ring-closing metathesis and selective functionalization are typically employed to achieve the desired structure.
  • Research Potential: This compound's specific modifications, such as the methoxy and azatetracyclic groups, may influence its reactivity and biological effects, making it a subject of ongoing research. Its potential applications could extend to various fields, from medicinal chemistry to materials science.
  • Historical Context: The study of compounds like this one has evolved over decades, with chemists continually expanding their understanding of complex organic synthesis and structural biology, paving the way for breakthroughs in drug discovery and design.

Understanding such compounds not only enriches our knowledge of organic chemistry but also highlights the intricate connections between chemistry and biological systems. As we continue to explore compounds like 4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene, we unlock new possibilities for innovation in science and medicine.

Synonyms
RACEMETHORPHAN
3-Methoxy-17-methylmorphinan
CHEMBL22207
Dextromethorphan-d3
4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-triene
Racemethorphane
Racemetorfano
Racemethorphanum
Deoxydihydrothebacodine
510-53-2
avp-786
IDS-NR-001
DL-3-Methoxy-N-methylmorphinan
3-Methoxy-17-methylmorphinan, l
Levomethorpan
DL-methorphan
((-))-3-Methoxy-N-methylmorphinan
2H-10,4a-Iminoethanophenanthrene, 1,3,4,9,10,10a-hexahydro-6-methoxy-11-methyl-
Morphinan, 3-methoxy-N-methyl-, (-)-
Morphinan, 3-methoxy-17-methyl-, (-)-
Lopac0_000337
SCHEMBL503864
DTXSID60859238
CHEBI:146178
MKXZASYAUGDDCJ-UHFFFAOYSA-N
BCP09059
BCP28615
BBL033877
BDBM50003560
STL372945
AKOS037478323
CCG-204432
SDCCGSBI-0050325.P002
NCGC00015333-03
NCGC00015333-04
NCGC00162126-01
DB-041803
Levomethorphan; D-Methorphan; Delta-Methorphan
Morphinan, 3-methoxy-17-methyl-, (.+/-.)-
Q6823902
4-methoxy-17-methyl-17-azatetracyclo[7.5.3.0(1,10).0(2,7)]heptadeca-2(7),3,5-triene
4-methoxy-17-methyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2,4,6-triene
6-methoxy-11-methyl-1,3,4,9,10,10a-hexahydro-2H-10,4a-(epiminoethano)phenanthrene