Skip to main content

Propyphenazone

ADVERTISEMENT
Identification
Molecular formula
C14H18N2O
CAS number
67-51-6
IUPAC name
4-(isopropylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one
State
State

Propyphenazone is a solid at room temperature.

Melting point (Celsius)
92.00
Melting point (Kelvin)
365.15
Boiling point (Celsius)
322.00
Boiling point (Kelvin)
595.15
General information
Molecular weight
246.31g/mol
Molar mass
246.3090g/mol
Density
1.1835g/cm3
Appearence

Propyphenazone is generally found in a crystalline powder form, which can vary from white to slightly yellow. It is odorless and has a bitter taste.

Comment on solubility

Solubility of 4-(isopropylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one (C14H18N2O)

The solubility of 4-(isopropylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one is an important aspect to consider when evaluating its application and behavior in various environments. Solubility can significantly affect the compound's biological availability and reactivity. Here are some interesting points about its solubility:

  • Solvent Dependence: The solubility of this compound may vary widely depending on the solvent used. Generally, compounds with similar structures tend to dissolve better in solvents of comparable polarity.
  • Polarity Consideration: Given that this compound features both hydrophobic (the isopropyl and phenyl groups) and hydrophilic (amine and carbonyl groups) elements, it is likely to exhibit moderate solubility in polar solvents.
  • Hydrogen Bonding: The presence of the carbonyl oxygen may participate in intermolecular hydrogen bonding, which can further influence its solubility in aqueous solutions.
  • pH Sensitivity: As an amine-containing compound, it may have different solubility profiles at varying pH levels, potentially becoming more soluble in acidic solutions.

In summary, the solubility of 4-(isopropylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one is influenced by a range of factors including solvent type, polarity, intermolecular forces, and pH conditions. Understanding these factors is crucial for predicting its behavior in different chemical and biological systems.

Interesting facts

Interesting Facts About 4-(Isopropylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one

4-(Isopropylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one, commonly referred to in scientific literature, is an intriguing compound due to its unique structure and potential applications. Here are some notable insights about this compound:

  • Pharmacological Significance: This compound exhibits properties that make it a subject of interest in medicinal chemistry, particularly in the domain of analgesics and anti-inflammatory agents.
  • Structural Attributes: The pyrazolone ring, combined with the isopropylamino and phenyl groups, contributes to its stability and biological activity. The position of the substituents greatly influences its reactivity and interaction with biological targets.
  • Versatility: The compound’s structure allows for modifications that can lead to the development of derivatives with potentially enhanced properties, making it a valuable template in synthetic chemistry.
  • Research Potential: Ongoing research may explore its role in the treatment of various diseases, highlighting the importance of innovative compounds in drug discovery pipelines.
  • Synthesis Routes: The synthesis of this compound involves various organic reactions, including condensation and cyclization techniques, showcasing the beautiful complexity of organic synthesis.

In conclusion, 4-(isopropylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one is more than just a chemical; it represents a convergence of synthetic innovation and potential therapeutic developments. As we continue to explore its properties, we might uncover new avenues for enhancing human health.

Synonyms
Ramifenazone
3615-24-5
Isopyrin
Isopropylaminoantipyrine
Isopyrine
Ramifenazona
Ramifenazone [INN]
Isopropylaminophenazone
Tomanol-wirkstoff
Ramifenazonum
Ramifenazonum [Latin]
Ramifenazona [Spanish]
4-(Isopropylamino)antipyrine
4-(Isopropylamino)-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one
GKH2KOV2RF
UNII-GKH2KOV2RF
EINECS 222-791-3
1,5-dimethyl-2-phenyl-4-(propan-2-ylamino)pyrazol-3-one
1-Phenyl-2,3-dimethyl-4-isopropylaminopyrazolone
BRN 0231936
ANTIPYRINE, 4-(ISOPROPYLAMINO)-
DTXSID1045906
4-Isopropylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
Isopirina
1-Phenyl-2,3-dimethyl-4-(isopropylamino)-2-pyrazolin-5-one
RAMIFENAZONE [MI]
NSC-758621
RAMIFENAZONE [MART.]
3H-Pyrazol-3-one,1,2-dihydro-1,5-dimethyl-4-[(1-methylethyl)amino]-2-phenyl-
RAMIFENAZONE [WHO-DD]
4-Monoisopropylamino-1-phenyl-2,3-dimethyl-5-pyrazolone
4-Isopropylamino-1-phenyl-2,3-dimethyl-3-pyrazolin-5-one
DTXCID9025906
5-25-14-00123 (Beilstein Handbook Reference)
3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-((1-methylethyl)amino)-2-phenyl-
NSC 758621
Ramifenazonum (Latin)
RAMIFENAZONE (MART.)
1,2-Dihydro-1,5-dimethyl-4-((1-methylethyl)amino)-2-phenyl-3H-pyrazol-3-one
1,2-Dihydro-1,5-dimethyl-4-[(1-methylethyl)amino]-2-phenyl-3H-pyrazol-3-one
4-(ISOPROPYLAMINO)-1,5-DIMETHYL-2-PHENYL-1,2-DIHYDRO-3H-PYRAZOL-3-ONE
CAS-3615-24-5
NCGC00095073-01
1-Phenyl-2,3-dimethyl-4-(isopropylamino)-2-pyrazolin-5-one; 1-Phenyl-2,3-dimethyl-4-isopropylaminopyrazolone; 4-(Isopropylamino)antipyrine; 4-(Isopropylamino)phenazone; 4-Isopropylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one; 4-Monoisopropylamino-1-phenyl-2,3-dimethyl-5-pyrazolone
Spectrum_001528
Prestwick0_000722
Prestwick1_000722
Prestwick2_000722
Prestwick3_000722
Spectrum2_001592
Spectrum3_001908
Spectrum4_000831
Spectrum5_001523
SCHEMBL24763
BSPBio_000644
BSPBio_003476
KBioGR_001401
KBioSS_002008
DivK1c_000944
SPBio_001584
SPBio_002583
BPBio1_000710
CHEMBL157337
CHEBI:94776
KBio1_000944
KBio2_002008
KBio2_004576
KBio2_007144
KBio3_002980
NINDS_000944
4-(Isopropylamino)-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
HY-B1137
Tox21 111412
Tox21_111412
AKOS015841763
Tox21_111412_1
AB07302
CS-4742
KS-5044
IDI1_000944
NCGC00016735-01
NCGC00016735-02
NCGC00016735-03
NCGC00016735-06
NCGC00178042-01
NCGC00178042-02
AC-15649
SBI-0051848.P002
CAS-18342-39-7
NS00001099
G12657
AB00053676_08
BRD-K85333151-003-08-4
BRD-K85333151-003-13-4
Q27166556
1,5-dimethyl-2-phenyl-4-(propan-2-ylamino)-3-pyrazolone
1,5-Dimethyl-4-[(1-methylethyl)amino]-2-phenyl-1,2-dihydro-3H-pyrazol-3-one