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4-Hydroxybenzoic acid

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Identification
Molecular formula
C7H6O3
CAS number
99-96-7
IUPAC name
4-hydroxybenzoic acid
State
State

4-Hydroxybenzoic acid is a solid at room temperature. It is stable and non-volatile under standard conditions.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
336.00
Boiling point (Kelvin)
609.15
General information
Molecular weight
138.12g/mol
Molar mass
138.1220g/mol
Density
1.4600g/cm3
Appearence

4-Hydroxybenzoic acid typically appears as a white crystalline solid. The crystals are usually fine and exhibit a powdery texture.

Comment on solubility

Solubility of 4-Hydroxybenzoic Acid (C7H6O3)

4-Hydroxybenzoic acid, commonly known for its role in various chemical applications, exhibits interesting solubility characteristics. Understanding its solubility can help in various fields, from pharmaceuticals to materials science.

Key Points on Solubility:

  • Solvent Dependence: 4-hydroxybenzoic acid is soluble in polar solvents such as water and ethanol, indicating that its hydroxyl group enhances interaction with solvent molecules.
  • Temperature Influence: As with many organic compounds, the solubility of 4-hydroxybenzoic acid increases with temperature. Higher temperatures increase molecular movement and interactions with the solvent.
  • pH Sensitivity: The solubility can vary with pH levels, as the acidic group may dissociate in basic solutions, increasing solubility.
  • Applications and Implications: Its solubility profile is crucial when formulating drugs or other products, as it affects bioavailability and the efficacy of the compound.

The interplay of these factors makes the solubility of 4-hydroxybenzoic acid a captivating subject in chemical studies. As noted, when discussing solubility, it is essential to consider not only the solvent but also the environmental conditions that can significantly influence the process.

Interesting facts

Interesting Facts About 4-Hydroxybenzoic Acid

4-Hydroxybenzoic acid, also known as para-hydroxybenzoic acid, is a fascinating compound widely recognized in the fields of chemistry and biochemistry. Here are some intriguing aspects of this compound:

  • Versatile Use: 4-Hydroxybenzoic acid serves as a building block for various organic reactions and is utilized in the synthesis of pharmaceuticals, cosmetics, and food preservatives.
  • Natural Occurrence: This compound is naturally found in plant metabolites, indicating its importance in natural product chemistry and its role in the metabolic pathways of certain organisms.
  • Esters and Derivatives: A significant characteristic of 4-hydroxybenzoic acid is its ability to form esters, notably parabens, which are widely used as preservatives in personal care products.
  • pH Sensitivity: The acidity of 4-hydroxybenzoic acid allows it to function effectively as an acid in various chemical reactions, making it an important compound for studying acid-base properties.
  • Industrial Applications: This compound is utilized in the production of dyes, plastics, and ceramics, highlighting its versatility beyond biological contexts.

As scientists continue to explore the applications of 4-hydroxybenzoic acid, its role in both synthetic chemistry and natural processes is becoming increasingly appreciated. Its broad range of functionality makes it an essential compound in both research and industry.

Synonyms
4-HYDROXYBENZOIC ACID
99-96-7
p-Hydroxybenzoic acid
4-Carboxyphenol
p-Salicylic acid
Benzoic acid, 4-hydroxy-
Benzoic acid, p-hydroxy-
p-carboxyphenol
para-Hydroxybenzoic acid
Paraben-acid
4-Hydroxybenzoesaeure
p-Oxybenzoesaure
Kyselina 4-hydroxybenzoova
p-Oxybenzoesaure [German]
NSC 4961
parahydroxybenzoic acid
Acido p-idrossibenzoico
4-hydroxy-benzoic acid
Hydroxybenzoic acid
HSDB 7233
Acido p-idrossibenzoico [Italian]
Kyselina 4-hydroxybenzoova [Czech]
EINECS 202-804-9
UNII-JG8Z55Y12H
CCRIS 8812
JG8Z55Y12H
DTXSID3026647
CHEBI:30763
HYDROXYBENZOIC ACID, PARA
p-hydroxy benzoic acid
AI3-01003
p-hydroxy-Benzoic acid
NSC-4961
Benzoic acid, 4-hydroxy
MFCD00002547
Hydroxybenzenecarboxylic acid
4-HBA
CHEMBL441343
DTXCID806647
FEMA NO. 3986
EC 202-804-9
3pcc
3pch
4-hydroxy-benzoate
4-hydroxy benzoic acid
4-Hydroxybenzoicacid
Benzoic acid, p-hydroxy
WLN: QVR DQ
PHB
CAS-99-96-7
NSC4961
SALICYLIC ACID IMPURITY A (EP IMPURITY)
SALICYLIC ACID IMPURITY A [EP IMPURITY]
DB04242
NCGC00166040-01
ACETYLSALICYLIC ACID IMPURITY A (EP IMPURITY)
ACETYLSALICYLIC ACID IMPURITY A [EP IMPURITY]
PROPYL HYDROXYBENZOATE IMPURITY A (EP IMPURITY)
PROPYL HYDROXYBENZOATE IMPURITY A [EP IMPURITY]
METHYL PARAHYDROXYBENZOATE IMPURITY A (EP IMPURITY)
METHYL PARAHYDROXYBENZOATE IMPURITY A [EP IMPURITY]
C00156
p-Salicylate
AE-848/32195059
p-hydroxy-Benzoate
4-hydoxybenzoic acid
4-hyroxybenzoic acid
phenol derivative, 8
4-hydroxylbenzoic acid
4-Hydroxy-benzoesaeure
4-hydroxybenzoi c acid
PHLORETIN_met004
4-hydroxyl benzoic acid
4-Hydroxybenzoate, III
AVOBENZONE_met002
para-hydroxy benzoic acid
bmse000092
bmse000583
SCHEMBL4110
BIDD:ER0706
4-Hydroxybenzenecarboxylic acid
p-Hydroxybenzoic Acid, Reagent
BDBM26194
HY-Y0264R
4-Hydroxybenzoic acid (Standard)
P-HYDROXYBENZOIC ACID [MI]
CS-D1180
HY-Y0264
STR01287
Tox21_202342
Tox21_303301
AC-008
BBL011981
s3754
STL138745
4-HYDROXYBENZOIC ACID [FHFI]
4-HYDROXYBENZOIC ACID [HSDB]
4-Hydroxybenzoic acid, >=99%, FG
AKOS000119033
CCG-266143
FH64214
NCGC00166040-02
NCGC00257058-01
NCGC00259891-01
H0207
NS00005418
4-Hydroxybenzoic acid, ReagentPlus(R), 99%
EN300-21461
D86505
4-Hydroxybenzoic acid, ReagentPlus(R), >=99%
4-Hydroxybenzoic acid, puriss., >=99.0% (T)
Q229970
46DD083D-BFD3-4CE1-B2D9-6C6D5FEFD3D9
4-Hydroxybenzoic acid, Vetec(TM) reagent grade, 99%
2-3-4'-TRIHYDROXY-4-METHOXYBENZOPHENONE_met005
F2191-0237
Z104498098
2-3-DIHYDROXY-4-METHOXY-4'-ETHOXYBENZOPHENONE_met009
4-Hydroxybenzoic acid, certified reference material, TraceCERT(R)
4-Hydroxybenzoic acid, Pharmaceutical Secondary Standard; Certified Reference Material
InChI=1/C7H6O3/c8-6-3-1-5(2-4-6)7(9)10/h1-4,8H,(H,9,10
202-804-9
30729-36-3