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4-Guanidinobutanamide

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Identification
Molecular formula
C5H12N4O
CAS number
102029-65-8
IUPAC name
4-guanidinobutanamide
State
State

At room temperature, 4-Guanidinobutanamide is typically found in a solid state, often as a crystalline powder.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
306.00
Boiling point (Kelvin)
579.15
General information
Molecular weight
144.19g/mol
Molar mass
144.1860g/mol
Density
1.2300g/cm3
Appearence

4-Guanidinobutanamide typically appears as a white or off-white powder. It is often characterized by its crystalline solid form.

Comment on solubility

Solubility of 4-Guanidinobutanamide (C5H12N4O)

4-Guanidinobutanamide, with the chemical formula C5H12N4O, presents an intriguing profile when it comes to solubility. Its structure indicates a significant capacity for hydrogen bonding, which generally enhances its solubility in polar solvents. Here are some of the key points regarding its solubility:

  • Solvent Compatibility: This compound is expected to be highly soluble in water due to its guanidine functional group. The presence of hydroxyl (–OH) and amino (–NH2) groups facilitates strong interactions with water molecules.
  • Temperature Variation: Its solubility might increase with temperature, which is common for many organic compounds, allowing for greater dissociation in solution.
  • Organic Solvent Solubility: It may exhibit limited solubility in non-polar organic solvents due to the polar nature of its functional groups, which are less compatible with non-polar environments.
  • pH Influence: The solubility could also be influenced by the pH of the solution, potentially becoming more soluble in acidic or basic conditions where the guanidine group may protonate or deprotonate.

Overall, the solubility characteristics of 4-guanidinobutanamide provide insight into its potential applications in biochemical contexts, where solubility plays a critical role in its functionality.

Interesting facts

Interesting Facts About 4-Guanidinobutanamide

4-Guanidinobutanamide is a fascinating compound widely researched for its various applications in the field of biochemistry and pharmacology. This compound has garnered attention particularly due to its structural resemblance to the amino acids and its potential impact on biological systems.

Key Applications and Properties

  • Biological Activity: 4-Guanidinobutanamide is known to exhibit modulatory effects on certain enzymatic activities, making it a valuable compound in the study of metabolic processes.
  • Potential in Drug Development: Research has indicated that derivatives of this compound may play a role in developing therapeutics for various diseases, particularly in areas such as cancer and neurological disorders.
  • Role in Protein Interaction: The guanidine group present in its structure allows for strong interactions with other biomolecules, offering insights into protein-ligand interactions which are crucial in drug design.

Scientific Insights

Researchers are particularly interested in the compound's capability to enhance the efficacy of certain drugs through:

  • The stabilization of transition states in reactions.
  • Improving the bioavailability of other pharmaceutical compounds.

Its unique composition invites chemists to investigate new synthetic pathways and modifications that could enhance its properties even further. The exploration of 4-guanidinobutanamide serves as a potent reminder of how seemingly simple compounds can hold the key to significant scientific breakthroughs.

Conclusion

The study of 4-guanidinobutanamide opens up numerous avenues for research and potential applications. As we continue to uncover its mysteries, this compound exemplifies the intersection of theoretical and applied chemistry, illustrating how fundamental science can lead to innovative solutions in health and medicine.

Synonyms
Tiformin
4-Guanidinobutanamide
4210-97-3
4-guanidinobutyramide
4-carbamimidamidobutanamide
Tiformina
Tiformine
Tiforminum
4-(diaminomethylideneamino)butanamide
Tiformin [INN]
TYFORMIN
Tiformin [INN:BAN]
FZN0LJN8CC
UNII-FZN0LJN8CC
Tiformine [INN-French]
Tiforminum [INN-Latin]
Tiformina [INN-Spanish]
4-(carbamimidamido)butanamide
HL 523 [as hydrochloride]
CHEBI:18062
HL-523 FREE BASE
DTXSID50194948
4-guanidobutanamide
Tiformine (INN-French)
Tiforminum (INN-Latin)
Tiformina (INN-Spanish)
4-guanido-butyramide
HL 523 (AS HYDROCHLORIDE)
SCHEMBL828055
CHEMBL2105405
DTXCID90117439
AKOS011645149
C03078
Q27102795