Skip to main content

4-Ethyl-4-methylpiperidine-2,6-dione

ADVERTISEMENT
Identification
Molecular formula
C8H13NO2
CAS number
933-08-8
IUPAC name
4-ethyl-4-methyl-piperidine-2,6-dione
State
State

At room temperature, 4-ethyl-4-methylpiperidine-2,6-dione is typically in a solid state. It can be handled as a stable compound under normal conditions, requiring proper storage to maintain its integrity and prevent degradation.

Melting point (Celsius)
116.50
Melting point (Kelvin)
389.65
Boiling point (Celsius)
221.10
Boiling point (Kelvin)
494.25
General information
Molecular weight
155.21g/mol
Molar mass
155.2090g/mol
Density
1.1537g/cm3
Appearence

4-Ethyl-4-methylpiperidine-2,6-dione appears as a crystalline solid under ambient conditions. The compound typically exhibits a white to off-white color, and due to its crystalline nature, it may be present in various sizes of opaque or semi-translucent crystals.

Comment on solubility

Solubility of 4-ethyl-4-methyl-piperidine-2,6-dione

The solubility of 4-ethyl-4-methyl-piperidine-2,6-dione (C8H13NO2), known for its intriguing structural features, can be influenced by various factors. Below are some key points regarding its solubility:

  • Polarity: The presence of both carbonyl groups and nitrogen in the piperidine ring suggests that this compound exhibits some polar characteristics, which can enhance solubility in polar solvents.
  • Solvent Compatibility: While this compound may be expected to be more soluble in protic solvents (like water and alcohols), it can also find solubility in non-polar organic solvents due to its hydrocarbon-like structure.
  • Temperature Dependency: As with many organic compounds, temperature can play a critical role in solubility, potentially increasing as the temperature rises, making it more feasible to dissolve in various solvents.

It is noteworthy that, while the solubility might not be extensively documented, studies indicate that compounds with similar structures often find varying degrees of solubility. Thus, consulting specific experimental data or conducting solubility tests is recommended for precise applications.

In summary, the solubility of 4-ethyl-4-methyl-piperidine-2,6-dione will largely depend on its environment and the solvents involved, highlighting the complex interplay between molecular structure and solubility characteristics.

Interesting facts

Interesting Facts about 4-Ethyl-4-Methyl-Piperidine-2,6-Dione

4-Ethyl-4-methyl-piperidine-2,6-dione is a fascinating compound that falls under the category of piperidine derivatives. This compound is notable for its unique structural features, which lend it a variety of properties and potential applications. Here are some compelling aspects to consider:

  • Structure and Stability: The piperidine ring structure provides this compound with a stable framework. The presence of both the ethyl and methyl groups makes it a substituted derivative, enhancing its chemical reactivity.
  • Medical Applications: Due to its piperidine core, compounds like 4-ethyl-4-methyl-piperidine-2,6-dione are often studied for their potential pharmacological properties. Piperidine derivatives have been used in the design of various pharmaceuticals.
  • Reactivity: The diketone functionality in this compound can participate in nucleophilic addition reactions, making it useful in the synthesis of more complex organic molecules.
  • Synthetic Routes: The preparation of piperidine derivatives often involves several synthetic methodologies, including cyclization reactions. This can make the synthesis of 4-ethyl-4-methyl-piperidine-2,6-dione a subject of interest for organic chemists.
  • Research Potential: The exploration of 4-ethyl-4-methyl-piperidine-2,6-dione in medicinal chemistry is ongoing. Its unique structure may lead to the discovery of novel therapeutic agents.

In summary, 4-ethyl-4-methyl-piperidine-2,6-dione is not just a simple compound; it represents a gateway to further exploration in organic synthesis and medicinal chemistry. The compound exemplifies the significance of piperidine derivatives in modern drug development and research.

Synonyms
bemegride
64-65-3
3-Ethyl-3-methylglutarimide
4-ethyl-4-methylpiperidine-2,6-dione
Methetharimide
Megimide
Megibal
Bemegrid
Eukraton
Mikedimide
Zentraleptin
Megimid
Agipnon
Ahypnon
Antibarbi
Malysol
2,6-Piperidinedione, 4-ethyl-4-methyl-
Bemegrida
Bemigride
Benegrid
3-Methyl-3-ethylglutarimide
NP13
2,6-Dioxo-4-methyl-4-ethylpiperidine
4-Ethyl-4-methyl-2,6-dioxopiperidine
4-Ethyl-4-methyl-2,6-piperidinedione
4-Methyl-4-ethyl-2,6-dioxopiperidine
Glutarimide, 3-ethyl-3-methyl-
NSC 58187
NSC-58187
Megibal (TN)
57DQA39DO2
DTXSID0045250
BEMEGRIDE [INN]
BEMEGRIDE [JAN]
BEMEGRIDE [MI]
3,3-Methylethylilotarimide
BEMEGRIDE [MART.]
BEMEGRIDE [WHO-DD]
DTXCID8025250
NP 13
3-Ethyl-3-methylglutarimide;Bemegrid
.beta.-Ethyl-.beta.-methylglutarimide
.beta.-Methyl-.beta.-ethylglutarimide
CAS-64-65-3
NCGC00016288-01
BEMEGRIDE (MART.)
beta-Ethyl-beta-methylglutarimide
Ethylmethylglutarimide
Bemegridum
Bemegridum [INN-Latin]
Bemegrida [INN-Spanish]
beta-Methyl-beta-ethylglutarimide
EINECS 200-588-0
BRN 0116672
UNII-57DQA39DO2
AI3-52526
Bemegride [USP:INN:BAN:JAN]
MFCD00006673
BENEGRIDE
MAYLUSOL
Bemegride (JAN/INN)
Prestwick0_000882
Prestwick1_000882
Prestwick2_000882
Prestwick3_000882
2, 4-ethyl-4-methyl-
BSPBio_000664
SCHEMBL601065
SPBio_002883
BPBio1_000732
WLN: T6VMVTJ E2 E1
CHEMBL1214192
CHEBI:92269
ORRZGUBHBVWWOP-UHFFFAOYSA-
R07AB05
HMS1570B06
HMS2097B06
HMS3652P09
HMS3714B06
HMS3885L09
BCP18663
HY-B1326
NSC58187
Tox21_110352
s4197
GLUTARIMIDE,-ETHYL-3-METHYL-
AKOS001108082
CCG-220882
CS-4896
DB13740
3-ethyl-5-methyl-piperidine-2,6-dione
4-ethyl-4-methyl-piperidine-2,6-dione
NCGC00016288-02
NCGC00016288-06
NCGC00179483-01
DS-16419
FE106383
DB-054709
AB00376458
E0284
NS00035727
SW197218-3
EN300-18941
D01957
F17053
SBI-0636097.0001
AB00376458_04
Q792614
SR-01000872683
SR-01000872683-1
BRD-K14993104-001-03-4
BRD-K14993104-001-05-9
Z99599698
200-588-0
InChI=1/C8H13NO2/c1-3-8(2)4-6(10)9-7(11)5-8/h3-5H2,1-2H3,(H,9,10,11)