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4-(dimethylamino)antipyrine

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Identification
Molecular formula
C13H17N3O
CAS number
114-24-3
IUPAC name
4-(dimethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one
State
State

At room temperature, 4-(dimethylamino)antipyrine exists in a solid state. This crystalline compound is stable under normal conditions but should be stored properly to avoid degradation or reactions with moisture and chemicals in the environment.

Melting point (Celsius)
106.00
Melting point (Kelvin)
379.15
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.15
General information
Molecular weight
231.30g/mol
Molar mass
231.2860g/mol
Density
1.1890g/cm3
Appearence

4-(Dimethylamino)antipyrine presents as a crystalline solid that can appear in a whitish to yellowish hue. The compound is typically encountered in powdered form and is known for its solubility in certain organic solvents, exhibiting less solubility in water. This appearance can vary slightly due to the compound's interaction with light and humidity in its environment, potentially leading to minor color variations.

Comment on solubility

Solubility of 4-(Dimethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one (C13H17N3O)

The solubility characteristics of 4-(dimethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one are of considerable interest due to its unique chemical structure. This compound exhibits a moderate level of solubility in various solvents, which can depend on several factors. Here are some key points regarding its solubility:

  • Solvent Specificity: The solubility can vary significantly based on the solvent used. Typical organic solvents like ethanol and dimethyl sulfoxide (DMSO) tend to dissolve this compound well.
  • Temperature Influence: As with many organic compounds, increased temperature usually enhances solubility, enabling better interaction between solute and solvent molecules.
  • pH Sensitivity: The solubility may also be influenced by the pH of the solution due to the presence of functional groups that can gain or lose protons.
  • Crystallization Behavior: Upon cooling, solutions of this compound might lead to crystallization, making it essential to control the conditions during storage and use.

In conclusion, the solubility of 4-(dimethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one is critically dependent on factors such as the solvent employed, temperature, and the pH of the system. Understanding these solubility dynamics is key for applications in pharmaceutical formulations and chemical syntheses.

Interesting facts

Interesting Facts about 4-(Dimethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one

This compound, known as a derivative of pyrazolone, belongs to a class of compounds that often find various applications in pharmaceuticals and biological research. Here are some exciting insights:

  • Structure and Stability: The unique structure of this compound includes a pyrazolone ring, which is recognized for its potential in stabilizing various functional groups, contributing to the overall reactivity of the molecule.
  • Biological Relevance: Compounds in this family, particularly those containing dimethylamino groups, are often investigated for their biological properties, including anti-inflammatory and analgesic effects.
  • Research Potential: With growing interest in drug design, this compound can serve as a scaffold for synthesizing new pharmaceuticals. Its varied substitution patterns allow chemists to customize properties and explore new therapeutic avenues.
  • Synthesis: The synthesis of this compound typically involves multi-step reactions, introducing functionality that can result in high yields, making it an intriguing subject for synthetic chemists.
  • Colorimetric Properties: Many pyrazolone derivatives exhibit colorimetric changes, which are useful for developing dye indicators in chemical testing and analytical chemistry.

As you explore this compound, remember that compounds like 4-(dimethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one are not just fascinating in structure but also embody the nexus of chemistry and pharmacology, showcasing how the tiny world of molecules impacts larger biological systems.

Synonyms
AMINOPYRINE
aminophenazone
Amidopyrine
58-15-1
4-Dimethylaminoantipyrine
Dipyrine
Aminopyrin
Amidopyrazoline
Amidazophene
Pyramidon
Aminofenazone
Amidazophen
Amidophen
Brufaneuxol
Eufibron
Itamidone
Pyramidone
Dereuma
Febron
Dimethylaminoazophene
Amidophenazone
Aminophenazon
Dimethylaminoantipyrine
Amidofebrin
Amidofen
Amidopyrin
Anafebrina
Netsusarin
Dimethylaminophenazone
Amidazofen
Piromidina
Dimapyrin
Dipirin
Dipyrin
Febrinina
Hyparon
Novamidon
Piramidon
Pirazon
Piridol
Polinalin
Pyradone
4-(Dimethylamino)antipyrine
Mamallet-A
4-Dimethylaminophenazone
Amidazophenum
Aminofenazona
Aminopyrinum
4-Dimethylamino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
Dimethylamino-analgesine
Dimethylaminophenyldimethylpyrazolone
Dimethylaminophenazon
Aminopyrine [JAN]
Aminophenazonum
(Dimethylamino)phenazone
4-(Dimethylamino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
Antipyrine, 4-(dimethylamino)-
4-Dimethylamino-1-phenyl-2,3-dimethylpyrazolone
Aminofenazona [INN-Spanish]
Aminophenazonum [INN-Latin]
3H-Pyrazol-3-one, 4-(dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-
Aminophenazone [INN]
1,5-Dimethyl-4-dimethylamino-2-phenyl-3-pyrazolone
1-Phenyl-2,3-dimethyl-4-dimethylaminopyrazol-5-one
2,3-Dimethyl-4-dimethylamino-1-phenyl-5-pyrazolone
4-Dimethylamino-2,3-dimethyl-1-phenyl-5-pyrazolone
CCRIS 2907
Aminopyrine [JAN:NF]
HSDB 2135
Mamallet a
Dimethylaminophenyldimethylpyrazolin
NSC 4993
EINECS 200-365-8
Aminopyrine (JAN)
UNII-01704YP3MO
Aminophenazone (INN)
DTXSID7020504
3-Keto-1,5-dimethyl-4-dimethylamino-2-phenyl-2,3-dihydropyrazole
Dimethylaminophenyldimethylpyrazone
1-Phenyl-2,3-dimethyl-4-(dimethylamino)-5-pyrazolone
NSC-4993
AMINOPYRINE [MI]
MFCD00003142
4-Dimethylamino Antipyrine
AMINOPYRINE [HSDB]
4-(Dimethylamino)phenazone
3H-Pyrazol-3-one,4-(dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-
4-(Dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one
4-(dimethylamino)-1,5-dimethyl-2-phenylpyrazol-3-one
DTXCID70504
AMINOPHENAZONE [MART.]
MLS002154195
AMINOPHENAZONE [WHO-DD]
3-Pyrazolin-5-one, 4-(dimethylamino)-2,3-dimethyl-1-phenyl-
CHEBI:160246
01704YP3MO
CAS-58-15-1
NCGC00016257-04
Amidophenazon
Amidopyrinum
SMR001216566
4-(dimethylamino)-1,5-dimethyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one
Aminofenazona (INN-Spanish)
Aminophenazonum (INN-Latin)
1-Phenyl-2,3-dimethyl-4-dimethylaminopyrazolone-5
1,5-Dimethyl-2-phenyl-4-dimethylamino-3-pyrazolone
AMINOPHENAZONE (MART.)
Aminophenazon [German]
METAMIZOLE SODIUM MONOHYDRATE IMPURITY D [EP IMPURITY]
Aminofenazone [Italian]
Dimethyl-N-aminoantipyrine
4-DIMETHYLAMINO-1,5-DIMETHYL-2-PHENYL-1,2-DIHYDRO-3H-PYRAZOL-3-ONE
Dimethylaminophenazon [German]
dimethylaminoanalgesine
SR-05000001741
Dimethyl N aminoantipyrine
Piramidone
METAMIZOLE SODIUM MONOHYDRATE IMPURITY D (EP IMPURITY)
Prestwick_14
Prestwick0_000088
Prestwick1_000088
Prestwick2_000088
Prestwick3_000088
cid_6009
TimTec1_000737
3-keto-1,3-dihydropyrazole
Oprea1_080671
SCHEMBL26293
BSPBio_000016
4-N,N-Dimethylaminoantipyrine
4-Dimethylamino-2,3-dimethyl-1-phenylpyrazol-5-one
SPBio_001955
BPBio1_000018
CHEMBL288470
P-DIMETHYLAMINOANTIPYRINE
(DIMETHYLAMINO)ANALGESINE
(DIMETHYLAMINO)ANTIPYRINE
4-(dimethylamino)-1,5-dimethyl-2-phenyl-pyrazol-3-one
BDBM74258
N02BB03
NSC4993
4-(dimethylamino)-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one
HMS1536B11
HMS1568A18
HMS2092E10
HMS2095A18
HMS3039C06
HMS3652G13
HMS3712A18
Pharmakon1600-01500621
HY-B0533
Tox21_110333
Tox21_201544
Tox21_302830
NSC757388
s3209
STL356033
AKOS001590378
Tox21_110333_1
CCG-103785
DB01424
FD22312
NSC-757388
NCGC00016257-01
NCGC00016257-02
NCGC00016257-03
NCGC00016257-05
NCGC00016257-06
NCGC00016257-07
NCGC00016257-10
NCGC00090878-01
NCGC00090878-02
NCGC00090878-03
NCGC00175173-01
NCGC00175173-02
NCGC00256436-01
NCGC00259094-01
3-Pyrazolin-5-one,3-dimethyl-1-phenyl-
AC-12025
SBI-0207073.P001
WLN: T5NNVJ A1 BR& DN1&1 E1
DB-053161
NS00000319
SW196332-3
C07539
D00556
EN300-18532179
Q416503
SR-05000001741-1
SR-05000001741-3
SR-05000001741-4
4-(dimethylamino)-1,5-dimethyl-2-phenyl-3-pyrazolone
BRD-K12568846-001-04-7
BRD-K12568846-001-14-6
BRD-K12568846-001-15-3
BRD-K12568846-001-16-1
4-(dimethylamino)-1,5-dimethyl-2-phenyl-3-pyrazolin-3-one
4-Dimethylaminoantipyrine, reactive nitrogen species scavenger
4-(dimethylamino)-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one
4-(Dimethylamino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one #
pyrazole, 2,3-dihydro-4-dimethylamino-1,5-dimethyl-3-oxo-2-phenyl-
pyrazole, 4-dimethylamino-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-
Aminophenazone (4-Dimethylamino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one)
200-365-8
4-(Dimethylamino)-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one;4-(Dimethylamino)-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one;Amino pyrine
4-Dimethylamino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (4,4-Dimethylaminophenazone)