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Diisopropylphenylpyridinebutanamide

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Identification
Molecular formula
C20H28N2O
CAS number
null
IUPAC name
4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide
State
State

At room temperature, diisopropylphenylpyridinebutanamide is in a solid state. It is stable under standard conditions, but should be stored in a cool, dry place to prevent degradation or reaction with moisture in the air.

Melting point (Celsius)
269.80
Melting point (Kelvin)
542.95
Boiling point (Celsius)
529.30
Boiling point (Kelvin)
802.45
General information
Molecular weight
322.45g/mol
Molar mass
322.4520g/mol
Density
1.0567g/cm3
Appearence

Diisopropylphenylpyridinebutanamide typically appears as a crystalline solid. The exact color and form can depend on purity and processing methods, but it generally has a whitish to pale yellow appearance. Handling should be done under appropriate conditions to maintain its stability and appearance.

Comment on solubility

Solubility of 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide

The compound 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide, with the chemical formula C20H28N2O, exhibits intriguing solubility characteristics. Understanding its solubility is crucial for its applications in various chemical processes and formulations.

Solubility in Different Solvents

This compound's solubility can be appreciated when considering the following aspects:

  • Polar Solvents: Generally, amides tend to be soluble in polar solvents due to their ability to form hydrogen bonds. Thus, one might expect moderate solubility in water and methanol.
  • Non-Polar Solvents: The presence of multiple isopropyl groups suggests a likelihood of higher solubility in non-polar organic solvents such as chloroform and ethanol.

Factors Influencing Solubility

The solubility of this compound may be affected by:

  • Temperature: Increased temperatures often enhance the solubility of organic compounds.
  • Presence of Other Chemicals: The introduction of acids or bases may alter its solubility profile.
  • Polarity of the Environment: More polar environments may aid in dissolving the amide portion of the compound.

In summary, while the solubility of 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide can be characterized by its disposition to dissolve in both polar and non-polar solvents, the balance of its structural features plays a decisive role. The interplay between its specific functional groups and the solvent properties determines its ultimate solubility behavior. Understanding these nuances can lead to better handling and application of this interesting compound.

Interesting facts

Interesting Facts about 4-(Diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide

This compound belongs to a class of organic compounds known as amides, which play a significant role in various biochemical processes and pharmaceuticals. The unique structure of 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide lends itself to some fascinating properties and potential applications:

  • Pharmacological Potential: The presence of the diisopropylamino group suggests that this compound may exhibit interesting pharmacological activities, potentially acting as a modulator for different biological pathways.
  • Analogue of Important Drugs: Compounds belonging to the same class have been studied as potential therapeutics for various conditions, owing to their ability to interact with specific receptors in the body.
  • Synthesis Challenges: The synthesis of such complex molecules often requires multiple steps and careful conditions, reflecting the ingenuity of modern synthetic chemistry.
  • Structure-Activity Relationship (SAR): Changes in the substituents on the central carbon can greatly influence the biological activity of the compound, making it an intriguing subject for SAR studies.
  • Research Applications: Due to its unique structure, this compound could serve as a lead compound in drug design, where researchers explore its effects on different biological systems.

The exploration of compounds like 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide not only enhances our understanding of chemical interactions but also opens new avenues in drug discovery. As one researcher noted, “The intersection of chemistry and biology often reveals the most unexpected insights.”

In conclusion, 4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide represents a captivating area of study for chemists and pharmacologists alike, embodying the intricate dance between structure and function in the fascinating world of chemical compounds.

Synonyms
disopyramide
3737-09-5
Dicorantil
Disopiramida
Isorythm
Ritmodan
Lispine
Rythmodan P
Searle 703
Disopyramidum
Ritmilen
Disopyramidum [INN-Latin]
Dl-disopyramide
Disopiramida [INN-Spanish]
SC 7031
Disopyramide Free Base
(rs)-disopyramide
SC-7031
Searle-703
alpha-Diisopropylaminoethyl-alpha-phenylpyridine-2-acetamide
gamma-Diisopropylamino-alpha-phenyl-alpha-(2-pyridyl)butyramide
GFO928U8MQ
MFCD00057366
(+/-)-DISOPYRAMIDE
H 3292
CHEBI:4657
DTXSID1045536
alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide
2-Pyridineacetamide, alpha-(2-(bis(1-methylethyl)amino)ethyl)-alpha-phenyl-
EINECS 223-110-2
4-[di(propan-2-yl)amino]-2-phenyl-2-pyridin-2-ylbutanamide
CHEMBL517
UNII-GFO928U8MQ
disopiramide
4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide
DTXCID9025536
3737-09-5 (free base)
H-3292
4-(diisopropylamino)-2-phenyl-2-(pyridin-2-yl)butanamide
NCGC00015358-18
2-Pyridineacetamide, alpha-(2-(diisopropylamino)ethyl)-alpha-phenyl-
Disopyramidum (INN-Latin)
Disopiramida (INN-Spanish)
2-Pyridineacetamide, .alpha.-[2-[bis(1-methylethyl)amino]ethyl]-.alpha.-phenyl-
DISOPYRAMIDE (MART.)
DISOPYRAMIDE [MART.]
a-[2-(Diisopropylamino)ethyl]-a-phenyl-2-pyridineacetamide
Diisopyramide
(R)-Disopyramide
DISOPYRAMIDE (EP MONOGRAPH)
DISOPYRAMIDE [EP MONOGRAPH]
CAS-3737-09-5
Rythmodan P (TN)
SR-01000003039
ALPHA-[2-(DIISOPROPYLAMINO)ETHYL]-ALPHA-PHENYL-2-PYRIDINEACETAMIDE
2-PYRIDINEACETAMIDE, .ALPHA.-(2-(BIS(1-METHYLETHYL)AMINO)ETHYL)-.ALPHA.-PHENYL-
4-(diisopropylamino)-2-phenyl-2-(2-pyridyl)butanamide
NCGC00016985-01
Prestwick_681
Norpace (Salt/Mix)
Spectrum_001008
Disopyramide (Standard)
Prestwick0_000266
Prestwick1_000266
Prestwick2_000266
Prestwick3_000266
Spectrum2_001033
Spectrum3_000404
Spectrum4_000524
Spectrum5_000943
DISOPYRAMIDE [MI]
DISOPYRAMIDE [INN]
DISOPYRAMIDE [JAN]
D 7644
DISOPYRAMIDE [USAN]
DISOPYRAMIDE [VANDF]
Lopac0_000402
Lopac0_000411
SCHEMBL16153
BSPBio_000112
BSPBio_001928
KBioGR_001127
KBioSS_001488
MLS002222242
DISOPYRAMIDE [WHO-DD]
DivK1c_000489
SPBio_001245
SPBio_002331
BPBio1_000124
GTPL7167
SC 13957 (Salt/Mix)
SCHEMBL23931452
KBio1_000489
KBio2_001488
KBio2_004056
KBio2_006624
KBio3_001148
C01BA03
Disopyramide (JP17/USAN/INN)
DTXSID00904630
NINDS_000489
HMS1568F14
HMS2095F14
HMS2234G08
HMS3261A06
HMS3369O21
HMS3712F14
HMS3886E08
Disopyramide [USAN:INN:BAN:JAN]
Disopyramide 1.0 mg/ml in Methanol
Tox21_110727
Tox21_500402
BDBM50028893
HY-12533R
NSC791109
s5490
AKOS015894712
Tox21_110727_1
CCG-204495
DB00280
FD22542
LP00402
NSC-791109
SDCCGSBI-0050388.P006
IDI1_000489
NCGC00015358-04
NCGC00015358-05
NCGC00015358-06
NCGC00015358-08
NCGC00015358-09
NCGC00015358-10
NCGC00015358-11
NCGC00015358-12
NCGC00015358-13
NCGC00015358-14
NCGC00015358-15
NCGC00015358-19
NCGC00015358-24
NCGC00015358-25
NCGC00093829-01
NCGC00093829-02
NCGC00093829-03
NCGC00261087-01
AC-16018
BS-17145
DA-52588
HY-12533
SMR001307254
SY052319
SBI-0050388.P005
AB00053462
CS-0011990
D2793
EU-0100402
NS00003733
C06965
D00303
T70845
AB00053462_16
AB00053462_17
Q425120
SR-01000003039-3
4-Diisopropylamino-2-phenyl-2-(2-pyridyl)-butyramide
BRD-A29734509-001-03-8
BRD-A29734509-011-02-9
BRD-A29734509-011-06-0
BRD-A29734509-011-12-8
BRD-A29734509-011-13-6
SR-01000003039-10
4-(Diisopropylamino)-2-phenyl-2-(2-pyridinyl)butanamide
4-(Diisopropylamino)-2-phenyl-2-(2-pyridyl)butyramide
Z1556052559
4-(Diisopropylamino)-2-phenyl-2-(2-pyridinyl)butanamide #
4-DIISOPROPYLAMINO-2-PHENYL-2-(2-PYRIDYL)BUTYRAMIDE
Disopyramide, European Pharmacopoeia (EP) Reference Standard
4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanamide
(2RS)- 4-Bis(1-methylethyl)amino-2-phenyl-2-(pyridin-2-yl)butanamide
.alpha.-(2-(Diisopropylamino)ethyl)-.alpha.-phenyl-2-pyridineacetamide
.gamma.-Diisopropylamino-.alpha.-phenyl-.alpha.-(2-pyridyl)butyramide
2-Pyridineacetamide, .alpha.-[2-(diisopropylamino)ethyl]-.alpha.-phenyl-
4-[bis(propan-2-yl)amino]-2-phenyl-2-(pyridin-2-yl)butanimidic acid
alpha-[2-[Bis(1-methylethyl)amino]ethyl]-alpha-phenyl-2-pyridineacetamide
racemic 2-phenyl-2-(2-pyridyl)-4-[N,N-bis(1-methylethyl)amino]butanamide
a-[2-[Bis(1-methylethyl)amino]ethyl]-a-phenyl-2-pyridineacetamide;Disopyramide;Dicorantil
223-110-2