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4-(difluoromethyl)sulfonylbenzenecarboximidamide

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Identification
Molecular formula
C9H10FN3O2S
CAS number
Not Available
IUPAC name
(4-carbamimidoylphenyl)methanesulfonyl fluoride
State
State

This compound typically exists as a solid at room temperature.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
295.00
Boiling point (Kelvin)
568.15
General information
Molecular weight
240.24g/mol
Molar mass
240.2440g/mol
Density
1.4300g/cm3
Appearence

The compound appears as a solid, crystalline powder which may be white or off-white in color.

Comment on solubility

Solubility of (4-carbamimidoylphenyl)methanesulfonyl fluoride

(4-carbamimidoylphenyl)methanesulfonyl fluoride, with the chemical formula C9H10FN3O2S, showcases unique solubility characteristics that make it an intriguing compound for various applications.

Solubility Profile

This compound is primarily known for its solubility in:

  • Aqueous solutions: Limited solubility, indicating that it may not dissolve easily in water.
  • Organic solvents: It demonstrates better solubility in organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO).

The solubility of (4-carbamimidoylphenyl)methanesulfonyl fluoride can be influenced by factors like:

  • Temperature: Increased temperatures generally enhance the solubility of solids in solvents.
  • pH levels: Since this compound might contain functional groups that can react with acids or bases, altering the pH can significantly impact solubility.
  • Presence of salts: In some cases, the addition of salts can either increase or decrease solubility through mechanisms such as the "salting-in" or "salting-out" effects.

Understanding the solubility of (4-carbamimidoylphenyl)methanesulfonyl fluoride is crucial for its effective application in chemical reactions, where the dissolution behavior can dictate the rate of reaction and product formation.

In summary, while (4-carbamimidoylphenyl)methanesulfonyl fluoride has limited solubility in water, its behavior in organic solvents presents fascinating opportunities for its use in various chemical processes.

Interesting facts

Interesting Facts About (4-Carbamimidoylphenyl)methanesulfonyl Fluoride

(4-Carbamimidoylphenyl)methanesulfonyl fluoride is a compound that showcases the fascinating intersection of organic chemistry and medicinal applications. Here are some engaging facts about this intriguing molecule:

  • Versatile Reactivity: This compound is known for its ability to participate in various chemical reactions, including nucleophilic substitutions and the formation of sulfonamide derivatives.
  • Medicinal Chemistry: Compounds like (4-carbamimidoylphenyl)methanesulfonyl fluoride have potential roles in drug development, particularly in the design of inhibitors for enzymes such as proteases.
  • Functional Groups: The structure features both a sulfonyl fluoride and a carbamimidoyl moiety, which can contribute to its reactivity and biological properties.
  • Biological Applications: The sulfonyl fluorides are often regarded for their efficiency in acylating amino acids or modifying peptides, making them valuable tools in biochemical research.
  • Structure-Activity Relationship (SAR): Studying how variations in the structure of this compound affect its activity can reveal critical insights into designing more effective therapeutic agents.

In essence, the unique properties and potential applications of (4-carbamimidoylphenyl)methanesulfonyl fluoride make it a significant molecule for those exploring the realms of chemistry and pharmacology. As stated by many chemists, “The beauty of chemistry lies in the endless possibilities that each compound holds.”


This compound serves as a reminder of the intricate relationships between structure, reactivity, and function in the vast world of chemical compounds.

Synonyms
(4-carbamimidoylphenyl)methanesulfonyl fluoride
71933-13-6
(4-Amidinophenyl)methanesulfonyl fluoride
4-Amidinophenylmethanesulfonyl fluoride
(p-Amidinophenyl)methanesulfonyl fluoride
DTXSID90222219
Benzenemethanesulfonyl fluoride, 4-(aminoiminomethyl)-
SCHEMBL537872
CHEMBL1199253
DTXCID40144710
AKOS027378079
SDCCGSBI-0633745.P001
NCGC00186021-01
NCGC00186021-02
AS-67595
DB-367290
(4-carbamimidoylphenyl)methanesulfonylfluoride