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4-Aminophenol

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Identification
Molecular formula
C6H7NO
CAS number
123-30-8
IUPAC name
4-aminophenol
State
State

At room temperature, 4-Aminophenol is in a solid state. The crystalline structure provides a stable form suitable for handling and use in laboratory and industrial applications.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
284.00
Boiling point (Kelvin)
557.15
General information
Molecular weight
109.13g/mol
Molar mass
109.1260g/mol
Density
1.3290g/cm3
Appearence

4-Aminophenol appears as a white to light brown solid crystalline powder. It can have a faint, sweetish, and somewhat medicinal odor. The compound exhibits good crystallinity and is often used in the form of crystals or crystalline powder in various applications.

Comment on solubility

Solubility of 4-Aminophenol (C6H7NO)

4-Aminophenol is a versatile organic compound notable for its solubility profiles in various solvents. Here are some key points regarding its solubility:

  • Water Solubility: 4-Aminophenol is moderately soluble in water, with a solubility of around 1 g/100 mL at room temperature. This characteristic makes it suitable for several applications where aqueous solutions are required.
  • Solvent Compatibility: The compound exhibits good solubility in organic solvents such as:
    • Ethanol
    • Dimethyl sulfoxide (DMSO)
    • Acetone
  • Impact of pH: The solubility of 4-aminophenol can also be affected by the pH of the solution, as it has both amino and hydroxyl functional groups that may ionize or form hydrogen bonds under different conditions.

In summary, while 4-aminophenol shows moderate solubility in water, its compatibility with various organic solvents enhances its usefulness in pharmacological and chemical applications. Understanding its solubility behavior is crucial for optimizing its use in different formulations.

Interesting facts

Interesting Facts about 4-Aminophenol

4-Aminophenol, recognized by its IUPAC name, is a versatile organic compound that plays a significant role in various applications. This compound is an aromatic amine, featuring an amino group attached to a phenolic ring, and it is primarily used as an intermediate in chemical synthesis. Here are some fascinating insights about 4-Aminophenol:

  • Pharmaceutical Industry: 4-Aminophenol is known for its role in the synthesis of paracetamol (acetaminophen), a widely used analgesic and antipyretic drug.
  • Dyes and Pigments: It serves as a precursor in manufacturing azo dyes, imparting vibrant colors to textiles and other materials.
  • Photography: 4-Aminophenol is utilized in photographic developers, aiding in the production of high-quality images by enhancing contrast.
  • Safety Precautions: It is important to handle 4-Aminophenol with care as it can pose risks associated with exposure. Ensure the use of proper protective equipment when working with this compound.

In addition to these applications, it's fascinating to note that 4-Aminophenol also demonstrates antioxidant properties, making it an area of interest for further research in health-related fields. As a molecule, its chemical structure showcases a delightful synergy between aromaticity and functional reactivity, making it a staple study component in organic chemistry courses.

Overall, 4-Aminophenol stands as a testament to the intricate relationships between chemical properties and their practical applications in daily life, reflecting the essential role of chemistry in technological advancement.

Synonyms
4-aminophenol
123-30-8
p-aminophenol
4-hydroxyaniline
p-hydroxyaniline
Phenol, 4-amino-
Paranol
4-aminobenzenol
Certinal
Citol
Fouramine P
p-Hydroxyphenylamine
Rodinal
Ursol P Base
Azol
Benzofur P
Fourrine P Base
Pelagol P Base
Tertral P Base
Ursol P
Durafur Brown RB
Furro P Base
Nako Brown R
Renal AC
4-Amino-1-hydroxybenzene
Fourrine 84
Phenol, p-amino-
Para-aminophenol
Zoba Brown P Base
UNAL
BASF Ursol P Base
Pelagol Grey P Base
1-Amino-4-hydroxybenzene
C.I. Oxidation Base 6
p-Aminofenol
4-AMINO-PHENOL
NSC 1545
p-aminobenzenol
p-Aminofenol [Czech]
Aminophenol, p-
C.I. 76550
4-hydroxybenzenamine
4-hydroxyphenylamine
Paramidophenol
CCRIS 4146
DTXSID3024499
CHEBI:17602
HSDB 2640
CI 76550
4-amino phenol
UNII-R7P8FRP05V
EINECS 204-616-2
R7P8FRP05V
MFCD00007869
AI3-14872
NSC-1545
DTXCID504499
C.I. Oxidation Base 6A
EC 204-616-2
p-Aminophenol [UN2512] [Poison]
aniline, 4-hydroxy-
NCGC00090816-01
NCGC00090816-02
4-AMINOPHENOL (USP-RS)
4-AMINOPHENOL [USP-RS]
4-AMINOPHENOL (USP IMPURITY)
4-AMINOPHENOL [USP IMPURITY]
4NL
CAS-123-30-8
MESALAZINE IMPURITY A (EP IMPURITY)
MESALAZINE IMPURITY A [EP IMPURITY]
PARACETAMOL IMPURITY K (EP IMPURITY)
PARACETAMOL IMPURITY K [EP IMPURITY]
paraaminophenol
Energol
Kodelon
Takatol
para aminophenol
p-amino-phenol
4-aminophenol B
Amino-4-phenol
para-amino-phenol
Phenol, p-Amino
4-hydroxy-aniline
para-hydroxyaniline
Mesalazine Imp. A (EP); Paracetamol Imp. K (EP); 4-Aminophenol; Mesalazine Impurity A; Paracetamol Impurity K
4-azaniumylphenolate
phenol derivative, 9
Furro P (Salt/Mix)
Peltol P (Salt/Mix)
Pelagol CP (Salt/Mix)
4-hydroxy-1-aminobenzene
Futramine P (Salt/Mix)
WLN: ZR DQ
bmse000462
Epitope ID:117708
4-Aminophenol, >=98%
Buprofezin metabolite BF22
P-AMINOPHENOL [MI]
SCHEMBL3424
CHEMBL1142
Durafur Brown R (Salt/Mix)
MLS001066356
4-AMINOPHENOL [HSDB]
Pelagol Grey CP (Salt/Mix)
SGCUT00256
SCHEMBL15663694
BDBM26195
NSC1545
BCP25857
to_000006
4-Aminophenol, >=99% (HPLC)
Tox21_113242
Tox21_113477
Tox21_201030
MSK000161
STK286017
4-Aminophenol, technical grade, 95%
AKOS000119829
AKOS016371265
Tox21_113477_1
CCG-266045
DB14144
FA05467
SB40549
UN 2512
NCGC00090816-03
NCGC00090816-04
NCGC00090816-05
NCGC00258583-01
AS-54109
SMR000471841
1ST000161
A0384
CS-0006652
NS00006730
EN300-33645
C02372
P17510
4-Aminophenol, PESTANAL(R), analytical standard
AJ-333/25022099
1-Amino-4-hydroxybenzene;4-Hydroxy-1-aminobenzene
Q2548040
Z57127517
F2190-0438
4-Aminophenol, United States Pharmacopeia (USP) Reference Standard
InChI=1/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H
Mesalazine impurity A, European Pharmacopoeia (EP) Reference Standard
4-Aminophenol, 250 mug/mL in acetonitrile, certified reference material, ampule of 1 mL
BEAUTIFUL WOMANS HAIR LOVES COLORFUL BUBBLES HAIR DYE 5N NATURAL BROWN
1-Amino-4-hydroxybenzene 4-Amino-1-hydroxybnzene 4-Aminobenzenol 4-amino-pheno
204-616-2