Interesting facts
Interesting Facts about 4-(Aminomethyl)benzenesulfonamide
4-(Aminomethyl)benzenesulfonamide, commonly known as AMS, is an intriguing compound that is widely used in medicinal chemistry and pharmaceuticals. Here are some fascinating insights:
- Pharmaceutical Applications: AMS plays a crucial role in the synthesis of various pharmaceuticals, particularly as a component in drug development for treating infectious diseases.
- Mechanism of Action: It is effective in inhibiting the enzyme dihydropteroate synthase, thus acting as a potential antibacterial agent. This makes it significant in combating microbial infections.
- Sulfonamide Family: As a member of the sulfonamide group, AMS shares a unique trait with other compounds in this family, which is their sulfonamide functional group that contributes to their biological activity.
- Research Utility: Beyond its clinical applications, AMS is often used in laboratory settings to study enzyme kinetics and mechanisms of action in biochemical research.
- Structural Importance: The presence of both an amine and a sulfonamide group enhances its solubility and reactivity, making AMS an important target in drug design.
In summary, 4-(Aminomethyl)benzenesulfonamide is more than just a chemical compound; it is a vital player in the realm of medicinal chemistry, contributing significantly to the development of antibiotic therapies and providing rich opportunities for scientific exploration. As the field continues to evolve, compounds like AMS remain at the forefront of innovation in combatting bacterial resistance and enhancing therapeutic efficacy.
Synonyms
mafenide
138-39-6
4-(Aminomethyl)benzenesulfonamide
4-Aminomethylbenzenesulfonamide
Sulfamylon
Emilene
Ambamide
Benzamsulfonamide
Homosulfanilamide
Benzenesulfonamide, 4-(aminomethyl)-
Malfamin
Maphenid
Maphenide
Homonal
Homosul
Marprontil
Mesudrin
Neofamid
Paramenyl
Septicid
Mesudin
4-Homosulfanilamide
Homosulfaminum
Mafenida
4-(aminomethyl)benzene-1-sulfonamide
Bensulfamide
Mafenidum
p-(Aminomethyl)benzenesulfonamide
4-sulfamoylbenzylamine
NSC-34632
Maphenidum
alpha-Amino-p-toluenesulfonamide
Mafenidum [INN-Latin]
Mafenida [INN-Spanish]
4-Homosufanilamide
EINECS 205-326-9
4-(aminosulfonyl)benzylamine
NSC 34632
UNII-58447S8P4L
D06BA03
.alpha.-Amino-p-toluenesulfonamide
p-Toluenesulfonamide, alpha-amino-
CHEMBL419
58447S8P4L
p-Aminomethylbenzenesulfonamide
CHEBI:6633
DTXSID6047860
NSC34632
p-Toluenesulfonamide, .alpha.-amino-
Mafenidum (INN-Latin)
Mafenida (INN-Spanish)
MAFENIDE (MART.)
MAFENIDE [MART.]
Mafenide [USAN:INN:BAN]
NCGC00016403-01
CAS-138-37-4
6LH
MFCD00072084
Masudin (Salt/Mix)
Marfanil (Salt/Mix)
Spectrum_000885
MAFENIDE [USAN]
Mafenide (USAN/INN)
MAFENIDE [INN]
MAFENIDE [MI]
4-sulfamoyl-benzyl-amine
MAFENIDE [VANDF]
Prestwick0_000166
Prestwick1_000166
Prestwick2_000166
Prestwick3_000166
Spectrum2_000095
Spectrum3_000482
Spectrum4_000034
Spectrum5_000916
Homosulfamine (Salt/Mix)
MAFENIDE [WHO-DD]
benzylamine, 4-sulphamoyl-
Oprea1_593766
Oprea1_661906
SCHEMBL41628
BSPBio_000031
BSPBio_001943
KBioGR_000467
KBioSS_001365
BIDD:GT0346
DivK1c_000363
SPBio_000050
SPBio_001952
aromatic sulfonamide compound 6
BPBio1_000035
4-Aminomethyl-benzenesulfonamide
4-aminomethyl-benzenesulphonamide
DTXCID2027836
BDBM10860
GTPL12697
KBio1_000363
KBio2_001365
KBio2_003933
KBio2_006501
KBio3_001443
NINDS_000363
BCPP000172
ALBB-014887
HY-B0614
aromatic/heteroaromatic sulfonamide 5
BBL012326
STK083032
TQ0026
AKOS001074998
BCP9000891
DB06795
GS-4341
SDCCGMLS-0003097.P003
IDI1_000363
NCGC00016403-02
NCGC00016403-03
NCGC00016403-04
NCGC00016403-11
BCP0726000212
SBI-0051431.P003
DB-002011
4-(AMINOMETHYL)-1-BENZENESULFONAMIDE
AB00053492
NS00007705
benzenesulfonamide, 4-(aminomethyl)-, acetate
EN300-35248
C07106
D02351
AB00053492_18
Q3843044
BRD-K30649484-003-13-7
205-326-9
Solubility of 4-(Aminomethyl)benzenesulfonamide
4-(Aminomethyl)benzenesulfonamide, with the chemical formula C7H10N2O2S, exhibits notable solubility characteristics due to its functional groups and overall structure. The presence of the sulfonamide group enhances its solubility in water, making it a polar compound. Here are some key points:
In summary, 4-(aminomethyl)benzenesulfonamide's solubility is predominantly governed by its polar sulfonamide functional group that facilitates interaction with solvents, particularly water. This compound serves as an excellent example of how molecular structure can significantly influence solubility properties.