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4-Aminoisoxazolidin-3-one

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Identification
Molecular formula
C3H6N2O2
CAS number
77428-66-3
IUPAC name
4-aminoisoxazolidin-3-one
State
State

At room temperature, 4-Aminoisoxazolidin-3-one is a solid. It is stable under normal conditions, but care should be taken when handling it to avoid moisture which could potentially compromise its stability and appearance.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
100.09g/mol
Molar mass
100.0880g/mol
Density
1.4321g/cm3
Appearence

The compound typically appears as a white crystalline solid, though it may exhibit a range of off-white shades depending on purity. Its crystalline nature allows it to form well-defined structures that can be seen under magnification.

Comment on solubility

Solubility of 4-aminoisoxazolidin-3-one (C3H6N2O2)

The solubility of 4-aminoisoxazolidin-3-one is an important property that can influence its applications and behavior in various environments. This compound exhibits moderate solubility in water, attributed to its polar functional groups. Understanding its solubility can provide insights into:

  • Solvent Interaction: The presence of amino and hydroxyl groups enhances hydrogen bonding with water, leading to improved solubility.
  • Concentration Effects: Its solubility can vary significantly with temperature and pH, which may alter its ionization state and interactions.
  • Functional Reactions: The solubility influences how 4-aminoisoxazolidin-3-one reacts chemically in solution, affecting its stability and reactivity.

As noted in scientific literature, "the solubility characteristics of amines can greatly affect their utility in pharmaceuticals." Therefore, understanding the solubility of 4-aminoisoxazolidin-3-one is essential for its effective application in medicinal chemistry and other related fields.


To better predict and manipulate its behavior in different systems, it is advisable to consider the following aspects:

  1. Thermal Stability: Monitoring how solubility changes with temperature can provide valuable information for practical applications.
  2. pH Sensitivity: Testing solubility across a range of pH levels can offer insights into its stability in biological systems.
  3. Solvent Variability: Conducting experiments with various organic solvents might reveal alternative solubility patterns useful for specific applications.

In summary, while 4-aminoisoxazolidin-3-one is moderately soluble in water due to its polar nature, exploring its solubility under different conditions is crucial for maximizing its potential in scientific and industrial applications.

Interesting facts

Interesting Facts about 4-aminoisoxazolidin-3-one

4-aminoisoxazolidin-3-one is a fascinating compound that has captivated the interest of chemists due to its unique structural features and potential applications. Below are some intriguing insights about this compound:

  • Heterocyclic Structure: The molecule contains a heterocyclic ring system with an isoxazolidine framework, which is notable for its stability and reactivity, making it a valuable subject for research in organic chemistry.
  • Pharmaceutical Potential: Compounds like 4-aminoisoxazolidin-3-one have been analyzed for their potential roles as intermediates in the synthesis of various pharmaceuticals, showcasing their utility in medicinal chemistry.
  • Biological Relevance: Research indicates that derivatives of this compound may exhibit biological activity, making it a candidate for studies in drug development and therapeutic applications.
  • Versatile Chemistry: The amino group present in the compound provides opportunities for further chemical modifications, allowing for the exploration of new derivatives with enhanced properties.
  • Synthetic Pathways: The synthesis of 4-aminoisoxazolidin-3-one is of interest in organic synthesis, where chemists are constantly seeking efficient pathways to create complex molecules.

Quote: "Understanding the intricate dance of atoms in compounds like 4-aminoisoxazolidin-3-one unlocks the potential for innovation in fields ranging from pharmaceuticals to materials science."

This compound is a testament to the remarkable diversity of chemical compounds and their implications in advancing scientific knowledge and applications. Each discovery brings us one step closer to harnessing their full potential!

Synonyms
DL-Cycloserine
4-Aminoisoxazolidin-3-one
68-39-3
4-Amino-3-isoxazolidinone
4-amino-1,2-oxazolidin-3-one
rac Cycloserine
3-Isoxazolidinone, 4-amino-
DL-4-Aminoisoxazolidin-3-one
(+-)-4-Amino-3-isoxazolidinone
DL-4-Amino-3-isoxazolidinone
4-Amino-3-isoxazolidone
C3H6N2O2
DTXSID40859074
3-Isoxazolidinone, d-
3-Isoxazolidinone, (R)-
3-Isoxazolidinone, (+)-
WLN: T5OMVJ DZ -D
Cycloserine, D-
.alpha.-Cycloserine
NSC154851
(+-)-Oxamicina [Italian]
(+-)-Oxamicina
EINECS 200-687-9
(+-)-4-Amino-3-isossazolidone [Italian]
AI3-61058
(+-)-4-Amino-3-isossazolidone
3-ISOXAZOLIDINONE, 4-AMINO-, (+-)-
Cycloserine, DL-
MFCD00064323
3-Isoxazolidinone,4-amino-, (4R)-
4-amino-4,5-dihydro-1,2-oxazol-3-ol
DL-Cycloserine crystalline
LS6CN6T9ND
4-Amino-isoxazolidin-3-on
DL-Cycloserine, crystalline
4-Amino-isoxazolidin-3-one
Lopac0_000267
SCHEMBL34323
4-amino-2-isoxazoline-3-ol
4-Amino-3-isoxazolidinone #
CHEBI:23503
CHEBI:27792
DTXCID10209224
HMS3260F16
HMS3370D10
HMS3374E09
HMS3393C15
Pharmakon1600-01506178
BCP22967
BCP22968
NSC76029
DL-4-amino-1,2-oxazolidin-3-one
Tox21_500267
(+/-)-3-Oxoisooxazolidin-4-amine
BBL016489
NSC760409
STK177281
STL454326
AKOS005410669
CCG-204362
CS-W008440
FR27495
LP00267
SB23044
SDCCGSBI-0050255.P002
NCGC00015213-04
NCGC00015213-05
NCGC00015213-06
NCGC00015213-07
NCGC00015213-08
NCGC00015213-11
NCGC00093725-01
NCGC00093725-02
NCGC00093725-03
NCGC00093725-04
NCGC00260952-01
BP-20174
DS-18396
SY005636
DB-055147
DB-055151
DB-068913
D-Cycloserine; D-4-Amino-3-isoxazolidinone
EU-0100267
NS00078925
NS00079493
C 7005
C06682
EN300-118713
SR-01000075776
SR-01000075776-1
Q27109800
Z336087816
Cycloserine; Seromycin; Orientomycin; Oxamycin; Seromycin
(S)-4-Amino-3-isoxazolidone; (S)-Cycloserine;Levcycloserine
4-Amino-3-isoxazolidinone;(+/-)-3-Oxoisooxazolidin-4-amine;DL-Cycloserine
200-687-9