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Tranexamic acid

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Identification
Molecular formula
C8H15NO2
CAS number
1197-18-8
IUPAC name
4-[amino(carboxy)methyl]benzoic acid
State
State

At room temperature, tranexamic acid is in a solid state, presenting itself as a stable crystalline powder.

Melting point (Celsius)
386.00
Melting point (Kelvin)
659.15
Boiling point (Celsius)
264.00
Boiling point (Kelvin)
537.15
General information
Molecular weight
157.21g/mol
Molar mass
157.2110g/mol
Density
1.2020g/cm3
Appearence

Tranexamic acid appears as a white crystalline powder. It is odorless and typically provided in a finely divided form, making it easy to work with in pharmaceutical applications.

Comment on solubility

Solubility of 4-[amino(carboxy)methyl]benzoic acid (C8H15NO2)

The solubility of 4-[amino(carboxy)methyl]benzoic acid is influenced by its molecular structure, which contains both amino and carboxylic acid functional groups. These groups play a significant role in its interactions with solvents, especially water.

Key Characteristics of Solubility:

  • Polar Nature: The presence of the amino (-NH2) and carboxylic acid (-COOH) groups imparts a strong polar character to the molecule.
  • Hydrophilic Interaction: Due to these polar functional groups, 4-[amino(carboxy)methyl]benzoic acid is expected to dissolve well in polar solvents like water.
  • pH Dependency: Its solubility can change with the pH of the solution, as the carboxylic acid can donate a proton (H+) under alkaline conditions, potentially enhancing solubility.
  • Temperature Influence: Like many organic compounds, the solubility of this compound may also increase with temperature, facilitating greater dissolution in aqueous solutions.

In conclusion, we can say that 4-[amino(carboxy)methyl]benzoic acid holds promise for solubility in water due to its functional groups, making it a compound of interest in various chemical applications. Its solubility characteristics can vary based on external factors such as pH and temperature.

Interesting facts

Interesting Facts about 4-[Amino(carboxy)methyl]benzoic Acid

4-[Amino(carboxy)methyl]benzoic acid, also known as p-aminobenzoic acid (PABA), is a fascinating compound with a range of applications in different fields. Here are some intriguing aspects of this compound:

  • Biological Significance: PABA plays a crucial role as a precursor in the synthesis of folic acid in bacteria and is involved in various metabolic processes in living organisms.
  • Cosmetic Uses: It is widely used in the formulation of sunscreen products, as it helps absorb UV radiation, thus protecting the skin from harmful solar rays.
  • Medicinal Applications: PABA has been explored for its potential benefits in enhancing the effectiveness of certain medications, particularly in conditions related to skin health.
  • Historical Context: Initially identified in the 19th century, PABA sparked interest due to its relation to para-aminobenzoic acid and its involvement in folic acid metabolism.
  • Natural Occurrence: It can be found naturally in various foods, including grains, liver, and eggs, indicating its importance in the human diet.

Quote: "The discovery of PABA opened new avenues in both biochemistry and dermatology, illustrating the interconnectedness of chemistry with health and wellness."

In conclusion, 4-[Amino(carboxy)methyl]benzoic acid not only holds significance in pharmacy and cosmetic science but also reveals the intricate relationship between chemical compounds and biological functions. Understanding such compounds allows scientists and students alike to appreciate the broader implications of chemistry in everyday life.

Synonyms
7292-81-1
(RS)-4-Carboxyphenylglycine
4-carboxyphenylglycine
4-[amino(carboxy)methyl]benzoic acid
4-Carboxylphenylglycine
4-(Amino(carboxy)methyl)benzoic acid
4-CPG
(RS)-4CPG
CHEMBL328984
(S)-4-Carboxyphenylglycine;4CPG
4-(Amino-carboxy-methyl)-benzoic acid
4CPG
4-[(1S)-1-Amino-2-hydroxy-2-oxo-ethyl]benzoic acid
Benzeneacetic acid, alpha-amino-4-carboxy-, (+-)-
SCHEMBL2266884
DTXSID70864035
CHEBI:178134
4-(Amino(carboxy)methyl)benzoicacid
BDBM50030629
MFCD00673852
NSC644612
AKOS023158559
NSC-644612
(R,S)-4-Carboxy-3-hydroxyphenylglycine
NCI60_015099
TS-08319
NS00015289
F14594
(+-)- alpha-amino-4-carboxy-Benzeneacetic acid
4-(Amino-carboxy-methyl)-benzoic acid(S-4CPG)
L001308
SR-01000597634
SR-01000597634-1
(RS)-4-Carboxyphenylglycine (H-DL-Phg(4-CO2H)-OH)