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4-Aminobenzoic acid

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Identification
Molecular formula
C7H7NO2
CAS number
150-13-0
IUPAC name
4-aminobenzoic acid
State
State

At room temperature, 4-aminobenzoic acid remains in a solid state. It is commonly used in labs and is stable under ambient conditions, making it easy to store and handle.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.00
Boiling point (Celsius)
268.00
Boiling point (Kelvin)
541.00
General information
Molecular weight
137.14g/mol
Molar mass
137.1390g/mol
Density
1.3740g/cm3
Appearence

4-Aminobenzoic acid appears as a white crystalline solid. It is often encountered in the form of fine, needle-like crystals or powder. The compound is known for its purity and can be handled as a typical organic synthetic reagent with standard lab safety procedures.

Comment on solubility

Solubility of 4-Aminobenzoic Acid (C7H7NO2)

4-Aminobenzoic acid, commonly known as para-aminobenzoic acid (PABA), exhibits **moderate solubility** in various solvents. Its solubility characteristics can be summarized as follows:

  • Water: 4-Aminobenzoic acid is reasonably soluble in water at room temperature. The solubility increases with temperature, due to its ability to form hydrogen bonds with water molecules.
  • Organic Solvents: It is soluble in many polar organic solvents, such as ethanol and methanol, due to its polar functional groups. However, it is less soluble in nonpolar solvents.
  • pH Dependence: The solubility is also influenced by the pH of the solution. At acidic pH levels, 4-aminobenzoic acid remains mostly in its non-ionized form, while at higher pH levels, it may become ionized, affecting solubility.

In conclusion, the solubility of 4-aminobenzoic acid can be quite variable, depending on the solvent and conditions. It is important to consider these factors when working with this compound in practical applications.

Interesting facts

Interesting Facts about 4-Aminobenzoic Acid

4-Aminobenzoic acid, commonly known as PABA, is a fascinating organic compound with a variety of important applications. Here are some noteworthy aspects of this compound:

  • Structure and Function: PABA is an aromatic amine and carboxylic acid. Its structure allows it to be a key component in the synthesis of folic acid, which is essential for bacterial growth and human health.
  • Biological Role: While PABA is not considered an essential nutrient for humans, it is involved in the synthesis of folate, another vital B-vitamin. In fact, "PABA is a building block for folic acid," emphasizing its role in human nutrition.
  • UV Protection: One of the most interesting uses of 4-aminobenzoic acid is in sunscreens. It acts as a UV filter, helping to protect the skin from the harmful effects of ultraviolet rays.
  • Medicinal Applications: PABA has been utilized in various medical treatments; it is known to have potential benefits in treating certain skin conditions, such as scleroderma and vitiligo.
  • Industrial Usage: Beyond its biological significance, PABA is also used in dye manufacturing and as a preservative in certain cosmetic products. Its versatility highlights its importance across different sectors.

In summary, 4-aminobenzoic acid is not merely a compound of interest for chemists, but it also plays significant roles in biology, medicine, and industry. Its multifaceted applications and essential role in folate synthesis make it a compound worth studying further.

Synonyms
4-aminobenzoic acid
150-13-0
p-aminobenzoic acid
PABA
para-aminobenzoic acid
AMINOBENZOIC ACID
Vitamin BX
p-Carboxyaniline
Benzoic acid, 4-amino-
4-Carboxyaniline
Hachemina
Paraminol
Sunbrella
p-Carboxyphenylamine
1-Amino-4-carboxybenzene
Pabacyd
Pabafilm
Pabamine
Paranate
Amben
Potaba
Romavit
Bacterial vitamin H1
Vitamin H'
Anticanitic vitamin
Chromotrichia factor
RVPaba Lipstick
Papacidum
Rvpaba
Trichochromogenic factor
Anti-chromotrichia factor
Super Shade by Coppertone
Benzoic acid, p-amino-
Acidum paraminobenzoicum
benzoic acid, 4-amino
Caswell No. 033B
4-azaniumylbenzoate
MFCD00007894
ABEE
Pabagel
Pabanol
4-AMINO-BENZOIC ACID
Kyselina p-aminobenzoova
Vitamin H1
p-Aminobenzoesaeure
4-Aminobenzoesaeure
4-Carboxyphenylamine
p-amino-Benzoic acid
Acido p-aminobenzoico
PAB
gamma-Aminobenzoic acid
Aminobenzoate
Actipol
CCRIS 6209
EPA Pesticide Chemical Code 233300
Acido p-aminobenzoico [Italian]
UNII-TL2TJE8QTX
BRN 0471605
HSDB 6840
Kyselina p-aminobenzoova [Czech]
Aminobenzoic acid (USP)
Aminobenzoic acid [USP]
AI3-02436
para-aminobenzoate
Anticantic vitamin
NSC 7627
NSC-7627
EINECS 205-753-0
gamma-Aminobenzoate
Trochromogenic factor
AMINOBENZOIC ACID, PARA
Aniline-4-carboxylate
DTXSID6024466
CHEBI:30753
P-AMINO-BENZOATE
TL2TJE8QTX
.gamma.-Aminobenzoic acid
Aniline-4-carboxylic acid
CHEMBL542
DTXCID404466
component of Presun (Salt/Mix)
P-AMINOBENZOIC ACID [MI]
4-Aminobenzoate, Potassium
AMINOBENZOIC ACID [MART.]
EC 205-753-0
AMINOBENZOIC ACID [USP-RS]
AMINOBENZOIC ACID [WHO-DD]
4-AMINOBENZOIC ACID [HSDB]
PARA-AMINOBENZOIC ACID [IARC]
PARA-AMINOBENZOIC ACID [VANDF]
NCGC00091051-01
AMINOBENZOIC ACID [USP MONOGRAPH]
4-AMINOBENZOIC ACID [EP IMPURITY]
4-AMINOBENZOIC ACID [EP MONOGRAPH]
4-aminobenzoic acid, potassium salt
trichromogenic factor
4 Aminobenzoic Acid, Potassium Salt
TETRACAINE HYDROCHLORIDE IMPURITY A [EP IMPURITY]
PROCAINE BENZYLPENICILLIN IMPURITY A [EP IMPURITY]
AMINOBENZOIC ACID (MART.)
Paraminan
AMINOBENZOIC ACID (USP-RS)
PARA-AMINOBENZOIC ACID (IARC)
AMINOBENZOIC ACID (USP MONOGRAPH)
CAS-150-13-0
SMR000471833
4-AMINOBENZOIC ACID (EP IMPURITY)
4-aminobenzoic-acid
4-AMINOBENZOIC ACID (EP MONOGRAPH)
p-amino benzoic acid
TETRACAINE HYDROCHLORIDE IMPURITY A (EP IMPURITY)
PROCAINE BENZYLPENICILLIN IMPURITY A (EP IMPURITY)
pCarboxyaniline
4Carboxyaniline
g-Aminobenzoate
Aminobenzoesaeure
4-amino-benzoate
4-ammoniobenzoate
Jumer Brand of Aminobenzoic Acid
Medea Brand of Aminobenzoic Acid
p-carboxy aniline
pCarboxyphenylamine
4aminobenzoic acid
amino benzoic acid
p-aminobezoic acid
Llorens Brand of Aminobenzoic Acid
4-aminobezoic acid
Acido paminobenzoico
g-Aminobenzoic acid
paraAminobenzoic acid
1Amino4carboxybenzene
Benzoic acid, pamino
4 - carboxy-aniline
4-Amino benzoic acid
Benzoic acid, 4amino
Kyselina paminobenzoova
4-(amino)benzoic acid
Antichromotrichia factor
Spectrum_000036
RVPaba lipstick (TN)
potassium-p-aminobenzoate
Spectrum2_000123
Spectrum3_000294
Spectrum4_000142
Spectrum5_000778
P-Aminobenzoic Acid,(S)
bmse000066
bmse000887
bmse000916
Epitope ID:115017
Llorens Brand of Aminobenzoic Acid Sodium Salt
SCHEMBL8249
4-Aminobenzoic acid, 99%
Oprea1_221096
Benzoic acid, amino-(8CI)
BSPBio_001828
KBioGR_000584
KBioSS_000396
MLS001066325
MLS001335919
MLS001335920
BIDD:ER0375
DivK1c_000783
4-aminobenzoic acid zwitterion
SPBio_000166
p-Aminobenzoic acid, Free Acid
4-Aminobenzoic acid (Standard)
SCHEMBL13232108
CHEBI:22495
HY-B1008R
KBio1_000783
KBio2_000396
KBio2_002964
KBio2_005532
KBio3_001328
MSK3401
NSC7627
CHEBI:194474
NINDS_000783
HMS2269E10
HMS3870E13
Benzoic acid, amino-(8CI)(9CI)
HY-B1008
Tox21_111069
Tox21_201702
Tox21_300087
BDBM50145829
s4510
STK397441
AKOS000118983
Tox21_111069_1
1ST3401
AC-8107
CCG-266139
CS-4505
DB02362
FA17692
Glenwood brand of Potassium Aminobezoate
IDI1_000783
USEPA/OPP Pesticide Code: 233300
4-Aminobenzoic acid, analytical standard
NCGC00091051-02
NCGC00091051-03
NCGC00091051-04
NCGC00253923-01
NCGC00259251-01
AS-12493
BP-31227
NCI60_041683
SY003749
SBI-0051277.P003
DB-028695
4-Aminobenzoic acid, ReagentPlus(R), 99%
A0269
NS00003125
4-Aminobenzoic acid, >=98.0% (HPLC/NT)
EN300-17988
4-Aminobenzoic acid, ReagentPlus(R), >=99%
C00568
D02456
Q284959
4-Aminobenzoic acid, Vetec(TM) reagent grade, 98%
4-Aminobenzoic acid, purified by sublimation, >=99%
BRD-K58497451-237-10-7
Z57127446
4-Aminobenzoic acid, 98.5-100.2%, SAJ first grade
4-Aminobenzoic acid, SAJ special grade, 99.5-100.2%
F2191-0259
4A5E7DD8-8A22-4642-86BF-05B778C0C78E
4-Aminobenzoic acid, European Pharmacopoeia (EP) Reference Standard
p-Aminobenzoic acid;Bacterial vitamin H1;p-Carboxyaniline;Vitamin H1
Aminobenzoic acid, United States Pharmacopeia (USP) Reference Standard
Aminobenzoic Acid, Pharmaceutical Secondary Standard; Certified Reference Material
215-310-3