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4-Aminobenzoate

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Identification
Molecular formula
C7H7NO2
CAS number
150-13-0
IUPAC name
4-aminobenzoate
State
State

At room temperature, 4-aminobenzoate typically exists in a solid state, often as a crystalline powder. The exact state will depend on the derivative or salt form that is being considered, but in its standard form, it is a solid.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
273.15
General information
Molecular weight
137.14g/mol
Molar mass
137.1410g/mol
Density
1.3740g/cm3
Appearence

4-Aminobenzoate, often used in the context of its salt forms (such as sodium 4-aminobenzoate), tends to appear as a white to light yellow crystalline powder. The appearance can vary slightly depending on the specific salt form and level of hydration.

Comment on solubility

Solubility of 4-aminobenzoate (C7H7NO2)

4-aminobenzoate, also known as P-aminobenzoic acid, exhibits specific solubility characteristics that are essential for its applications in various chemical and biological processes. Its solubility can be influenced by several factors, including:

  • Solvent Polarity: 4-aminobenzoate is generally more soluble in polar solvents, particularly in water, due to its ability to form hydrogen bonds.
  • Temperature: Increasing the temperature can enhance the solubility of 4-aminobenzoate in different solvents, making it easier to dissolve.
  • pH Levels: The solubility can also vary with pH, as the carboxyl group can exist in different ionic forms depending on the acidity or basicity of the solution.

In summary, 4-aminobenzoate demonstrates:

  • Moderate solubility in water.
  • Improved solubility at elevated temperatures and higher pH values.

Understanding these solubility parameters is crucial for applications such as pharmaceutical formulations and biological research, where the effectiveness of 4-aminobenzoate can significantly depend on its availability in the desired solvent environment.

Interesting facts

Interesting Facts about 4-Aminobenzoate

4-Aminobenzoate, often referred to as para-aminobenzoate or PABA, is a fascinating compound with a variety of applications and properties that spark interest in both the pharmaceutical and chemical fields. Here are some notable details:

  • 4-Aminobenzoate is an important intermediate in the synthesis of various drugs, particularly those related to sulfa medications, demonstrating its significance in medicinal chemistry.
  • This compound is known for its ability to absorb UV light, making it a common ingredient in sunscreens, thereby helping to protect human skin from harmful ultraviolet rays.
  • Interestingly, 4-aminobenzoate is not only synthesized but also occurs naturally as it is produced by gut bacteria in both humans and other mammals. This suggests a role in human health that merits further investigation.
  • PABA is also a key player in the synthesis of folic acid in certain microorganisms, which underscores its importance in biological systems.
  • Despite its beneficial properties, some individuals can experience allergic reactions to PABA, highlighting the necessity of caution in its use.

In summary, 4-aminobenzoate stands out as a compound of great relevance in both practical applications and scientific research. Its diverse roles in medicine and biology make it an intriguing subject for study, emphasizing the intricate connections between chemistry and health.

Synonyms
4-aminobenzoate
p-aminobenzoate
Benzoic acid, 4-amino-, ion(1-)
2906-28-7
trichromogenic factor
CHEMBL1762658
Papacidium
para-Aminobenzoates
Bacterial Vitamin H
4-Aminobenzoate ion
p-Aminobenzoate anion
3q2a
4-aminophenylcarboxylate
p-Aminobenzoic acid anion
4-Aminobenzoic acid-ion(1-)
Benzoic acid-p-amino-ion(1-)
4-aminobenzoic acid, ion(1-)
CHEBI:17836
DTXSID40183306
ALYNCZNDIQEVRV-UHFFFAOYSA-M
BDBM50340076
STK379527
AKOS005449626
NCGC00178975-01
CS-0164204
NS00115890
AB00053416_08
4-aminophenyl formate? (Sorafenib Impurity pound(c)
Q27102654