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Glutamic acid γ-semialdehyde

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Identification
Molecular formula
C5H9NO3
CAS number
1190-51-0
IUPAC name
4-amino-5-oxo-pentanoic acid
State
State

At room temperature, glutamic acid γ-semialdehyde is in the solid state. It is usually handled as a powder and is hygroscopic, meaning it can absorb moisture from the air.

Melting point (Celsius)
155.00
Melting point (Kelvin)
428.15
Boiling point (Celsius)
163.00
Boiling point (Kelvin)
436.15
General information
Molecular weight
131.13g/mol
Molar mass
131.1300g/mol
Density
1.4600g/cm3
Appearence

Glutamic acid γ-semialdehyde is typically a white or off-white crystalline powder. It may appear as colorless crystals under certain conditions. Due to its aldehyde group, it is quite reactive and needs to be stored properly to prevent decomposition or reaction with atmospheric oxygen.

Comment on solubility

Solubility of 4-amino-5-oxo-pentanoic acid

4-amino-5-oxo-pentanoic acid (C5H9NO3), often referred to in scientific literature as a crucial intermediate in metabolic pathways, exhibits unique solubility characteristics that merit attention.

This compound displays:

  • High solubility in water: The presence of both an amino group (-NH2) and a carboxylic acid group (-COOH) contributes significantly to its ability to dissolve in polar solvents, especially water.
  • Dependency on pH: The solubility can be influenced by the pH of the solution. For example, in acidic conditions, the carboxylic acid group is protonated, which may affect the net charge and solubility.
  • Minimal solubility in organic solvents: Non-polar organic solvents are generally ineffective at solubilizing this compound, primarily due to its polar functional groups which favor interactions with polar solvents.

In summary, the solubility of 4-amino-5-oxo-pentanoic acid is characterized by its strong affinity for polar solvents, making it readily soluble in aqueous environments while showing limited solubility in non-polar organic solvents. Understanding these solubility dynamics is essential for applications in biological and chemical processes.

Interesting facts

Interesting Facts about 4-amino-5-oxo-pentanoic acid

4-amino-5-oxo-pentanoic acid, often referred to in the scientific community as a unique amino acid derivative, holds significant intrigue due to its structural and functional properties:

  • Amino Acids Connection: This compound is related to amino acids, which are the building blocks of proteins. Its structure showcases elements typical of amino acids, indicating potential roles in biological processes.
  • Role in Metabolism: As an intermediate in certain metabolic pathways, this compound aids in the synthesis of other important biomolecules, making it vital in metabolic studies.
  • Research Applications: It is of particular interest in the field of medicinal chemistry. Researchers explore its potential interactions with enzymes, which could lead to the development of novel pharmaceuticals.
  • Biological Relevance: The presence of an amino group and a keto group in the molecule suggests potential reactivity that could be harnessed for various biochemical reactions.
  • Synthesis of Derivatives: 4-amino-5-oxo-pentanoic acid serves as a precursor for the synthesis of complex compounds, demonstrating its versatility within organic chemistry.

In summary, 4-amino-5-oxo-pentanoic acid is more than just a simple compound. Its unique properties position it as a focal point of research in several scientific disciplines, inspiring scientists to uncover its full potential in both biological and synthetic chemistry.

Synonyms
4-AMINO-5-OXO-PENTANOIC ACID
SCHEMBL68935
AKOS006386485
Q27460772