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4-amino-2-methyl-5-(phosphonomethyl)pyrimidine

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Identification
Molecular formula
C6H11N3O6P2
CAS number
14097-28-8
IUPAC name
(4-amino-2-methyl-pyrimidin-5-yl)methyl phosphono hydrogen phosphate
State
State

At room temperature, 4-amino-2-methyl-5-(phosphonomethyl)pyrimidine exists as a solid, which can be either in crystalline or amorphous form. It is stable under normal conditions and should be stored in a dry environment to prevent degradation.

Melting point (Celsius)
211.00
Melting point (Kelvin)
484.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
219.10g/mol
Molar mass
219.1030g/mol
Density
1.6700g/cm3
Appearence

It appears as a solid substance, typically amorphous or crystalline in nature. The compound may vary in color from off-white to pale yellow, depending on purity and specific batch characteristics.

Comment on solubility

Solubility of (4-amino-2-methyl-pyrimidin-5-yl)methyl phosphono hydrogen phosphate

The solubility of (4-amino-2-methyl-pyrimidin-5-yl)methyl phosphono hydrogen phosphate, represented by the chemical formula C6H11N3O6P2, is influenced by several factors that determine its behavior in various solvents.

Key Factors Affecting Solubility

  • Polarity: The presence of polar functional groups, particularly the phosphate moieties, suggests that this compound may exhibit a degree of solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with surrounding molecules can enhance solubility, indicating that this compound might dissolve well in aqueous solutions due to interactions with water molecules.
  • pH Dependence: As a phosphono compound, its solubility can vary significantly with changes in pH, where dissociation of protons from phosphate groups may further influence its solubility metrics.

It is essential to note that specific solubility data for this compound may be limited in available literature. However, based on its structural attributes, it is reasonable to posit that it would exhibit moderate solubility characteristics in suitable solvents.
Understanding and exploring its solubility is crucial for applications in biochemical and pharmaceutical contexts, highlighting the importance of comprehensive solubility studies.

Interesting facts

Interesting Facts About (4-amino-2-methyl-pyrimidin-5-yl)methyl phosphono hydrogen phosphate

(4-amino-2-methyl-pyrimidin-5-yl)methyl phosphono hydrogen phosphate is an intriguing compound with numerous applications in biochemistry and pharmaceuticals. Here's a closer look at some of its noteworthy features:

  • Biological Relevance: This compound contains a pyrimidine ring, which is a key structural component of nucleotides. Pyrimidines play a crucial role in the formation of DNA and RNA, facilitating the storage and transfer of genetic information.
  • Phosphorylation: The phosphono group in this compound is indicative of its potential role in phosphorylation processes. Phosphorylation is vital for regulating activity in proteins and enzymes, making it essential in cell signaling pathways.
  • Drug Development: As a phosphonate derivative, it has garnered interest for its potential therapeutic benefits in treating various diseases, including cancer and viral infections. Compounds like this can act as inhibitors of enzymes crucial for pathogen survival.
  • Research Significance: This compound serves as a useful model for studies on enzyme kinetics and mechanisms of action. It aids scientists in understanding how similar compounds can interact at the molecular level.

In the words of famed chemist Linus Pauling, “The best way to have a good idea is to have lots of ideas.” This compound exemplifies the idea that exploring diverse chemical structures can lead to innovative solutions in science and medicine.

Studying compounds such as (4-amino-2-methyl-pyrimidin-5-yl)methyl phosphono hydrogen phosphate not only enhances our understanding of chemistry but also opens doors to groundbreaking discoveries in health and disease management.

Synonyms
HMP-PP
841-01-0
(4-amino-2-methylpyrimidin-5-yl)methyl trihydrogen diphosphate
4-amino-2-methyl-5-diphosphooxymethylpyrimidine
4-amino-2-methyl-5-diphosphomethylpyrimidine
(4-amino-2-methylpyrimidin-5-yl)methyl phosphono hydrogen phosphate
C04752
SCHEMBL851328
CHEBI:16629
Q27102006