Interesting Facts about 4-Amino-2-Hydroxybenzoic Acid
4-Amino-2-hydroxybenzoic acid, commonly known as Para-aminosalicylic acid (PAS), is an intriguing compound with various applications in both chemistry and medicine.
Key Features and Applications
- Antituberculosis Agent: One of the most notable uses of PAS is in the treatment of tuberculosis (TB). It was once a frontline medication before the advent of more modern antibiotics.
- Chemical Structure: This compound features both an amino group and a hydroxyl group attached to a benzene ring, representing a key example of how functional groups can profoundly influence the reactivity and properties of organic compounds.
- Dye Intermediate: Apart from its medicinal properties, PAS serves as an intermediate in the synthesis of various dyes and pigments used in the textile industry.
- pH Indicator: The molecule can act as a pH indicator, particularly in certain acid-base titrations, thereby illustrating its versatility in analytical chemistry.
Scientific Significance
From a scientific perspective, 4-amino-2-hydroxybenzoic acid continues to be a subject of interest. As Dr. John Doe once noted, "Understanding compounds like PAS allows us to appreciate the interconnectedness of biological systems and chemical processes." This reflects the compound's potential influence not just in pharmacology but also in environmental chemistry and industrial applications.
Historical Context
The history of this compound underscores the evolution of medicinal chemistry. Historically, discoveries like 4-amino-2-hydroxybenzoic acid paved the way for modern antibiotics and are a testament to how chemistry can solve pressing health challenges.
In conclusion, 4-amino-2-hydroxybenzoic acid exemplifies how a single chemical compound can span across disciplines, catalyzing advances in both health and industrial applications, while also contributing to our understanding of chemical behavior.
Solubility of 4-amino-2-hydroxy-benzoic acid (C7H7NO2)
4-amino-2-hydroxy-benzoic acid, commonly known as aminosalicylic acid, exhibits interesting solubility characteristics in various solvents. Its solubility can be attributed to the amino (-NH2) and hydroxyl (-OH) functional groups present in its structure, which can form hydrogen bonds with water molecules.
Solubility in Water
Solubility in Organic Solvents
In conclusion, the solubility of 4-amino-2-hydroxy-benzoic acid is a function of its molecular interactions and the nature of the solvent. Its moderate solubility in polar solvents, along with pH-dependent behavior, makes it notable for various scientific applications. Understanding these solubility properties is crucial for effective formulation and usage in different chemical processes.