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Thiamine (Vitamin B1)

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Identification
Molecular formula
C12H17N4O4
CAS number
59-43-8
IUPAC name
4-amino-1-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidin-2-one
State
State

At room temperature, Thiamine is generally a solid.

Melting point (Celsius)
248.00
Melting point (Kelvin)
521.15
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.15
General information
Molecular weight
265.31g/mol
Molar mass
265.3140g/mol
Density
1.3000g/cm3
Appearence

Thiamine (Vitamin B1) appears as a white crystalline powder. It is generally odorless or may have a slight characteristic odor and is soluble in water.

Comment on solubility

Solubility of 4-amino-1-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidin-2-one

The compound 4-amino-1-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidin-2-one, with the molecular formula C12H17N4O4, exhibits interesting solubility characteristics that are essential for its applications. This compound is likely to be soluble in polar solvents due to the presence of multiple functional groups that can form hydrogen bonds.

Factors Influencing Solubility

  • Polarity: The hydroxyl groups (–OH) significantly increase the compound's polarity, enhancing its solubility in water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules facilitates better dissolution.
  • Chemical Structure: The presence of the tetrahydrofuran ring contributes to its overall solubility profile, allowing for interactions in various solvents.

It can be stated that:

"Solubility is a key property that dictates how a compound behaves in biological systems and affects its bioavailability."

While specific quantitative solubility data may not be available, predicting its solubility behavior can guide researchers in formulating and using this compound effectively in various applications such as drug development and organic synthesis.

Interesting facts

Interesting Facts about 4-amino-1-[4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidin-2-one

This compound, often referred to in scientific circles due to its intriguing structure and properties, belongs to the class of pyrimidines and demonstrates significant biological relevance. Here are some notable aspects:

  • Biological Activity: This compound exhibits a unique combination of amino and hydroxy functionalities, which can contribute to its role in various biological systems. Its potential implications in pharmacology are being investigated, particularly as a candidate for drug development.
  • Structural Characteristics: The molecule's core structure exhibits a pyrimidine ring fused with a tetrahydrofuran moiety. This combination is quite rare and indicates potential for diverse chemical reactivity and interaction with biological targets.
  • Research Potential: Given its structural complexity, this compound may serve as a starting point for the synthesis of analogues with enhanced biological activity or reduced toxicity. Chemists are particularly interested in the modulation of its functional groups to explore new therapeutic pathways.
  • Applications: Emerging studies suggest that compounds similar to this one may have applicability in treating conditions such as metabolic disorders and certain types of cancer, underscoring the importance of exploring compounds in this class.

As highlighted by various studies, the versatility of this compound makes it a valuable subject of research: "The unique blend of functionality provides opportunities for innovative therapeutic solutions." Researchers and students alike find themselves captivated by the potential and mystery surrounding such chemically rich compounds.

Synonyms
5-Me-dC
4-amino-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-2-one
5-Methyl-2'-deoxy-cytidine
SCHEMBL14450224
LUCHPKXVUGJYGU-UHFFFAOYSA-N
NSC607302
AKOS040759139
NSC-607302
LS-13830
NCI60_004697
PD046679
SY038094
DB-056746
5-Methyl-2 inverted exclamation mark -deoxycytidine