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Cytosine

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Identification
Molecular formula
C4H5N3O
CAS number
71-30-7
IUPAC name
4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,3,5-triazin-2-one
State
State

Solid at room temperature.

Melting point (Celsius)
320.00
Melting point (Kelvin)
593.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
111.10g/mol
Molar mass
111.1020g/mol
Density
1.6600g/cm3
Appearence

Cytosine typically appears as a white crystalline substance. It is part of nucleic acid structures in cells and is one of the four main bases in DNA and RNA.

Comment on solubility

Solubility of 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,3,5-triazin-2-one

This compound, with the chemical formula C4H5N3O, exhibits notable characteristics regarding its solubility in various solvents. Here’s a detailed exploration of its solubility properties:

  • Water Solubility: Due to the presence of multiple hydroxyl groups within its structure, this compound is expected to have good solubility in water.
  • Solvent Interaction: The polar nature of the hydroxymethyl and dihydroxy groups enhances interaction with polar solvents, which generally increases solubility.
  • Organic Solvents: While it is soluble in water, its solubility in non-polar organic solvents may be limited due to the strong hydrogen bonding capabilities presented by the hydroxyl groups.

Generally speaking, it can be summarized that:

  • This compound is likely to be highly soluble in water and aqueous solutions.
  • It may also demonstrate moderate solubility in certain polar organic solvents.
  • In non-polar solvents, solubility is anticipated to be quite low.

In conclusion, the solubility of this compound is intricately linked to its functional groups, which play a crucial role in determining its interaction with different solvents.

Interesting facts

Interesting Facts about 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,3,5-triazin-2-one

This compound, often referred to in scientific literature by its systematic name, stands out due to its unique structural features and potential applications. Here are several engaging insights:

  • Structural Complexity: The presence of both a triazinone ring and a tetrahydrofuran moiety showcases the intriguing interplay of various functional groups within the compound. This complexity can lead to unique chemical properties and reactivity.
  • Biological Relevance: Compounds that contain amino and hydroxyl groups are often found in biologically active molecules. This particular structure could potentially interact with biological systems, making it a candidate for pharmaceutical research or medicinal chemistry.
  • Synthesis Potential: The synthesis of such a compound may involve various chemical reactions, including condensation and ring-formation techniques, which can be a fascinating area of study for chemists interested in synthetic methodologies.
  • Versatile Applications: Due to its structural components, this compound could have applications in areas such as agricultural chemicals, pharmaceuticals, or even materials science, where new properties may emerge from its intricate structure.
  • Future Research: As scientists continue to explore the potential uses of compounds like this one, its impact on fields such as drug development and biochemistry cannot be understated. Researchers are always on the lookout for *novel* compounds that could lead to breakthroughs in treatment and technology.

In conclusion, 4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,3,5-triazin-2-one exemplifies how intricate molecular structures can lead to significant advancements in various scientific domains. As noted by a renowned chemist, “The beauty of chemistry lies in the infinite possibilities that arise from the combinations of simple ideas.”

Synonyms
Azacytidine, 5-
5-AZCR
4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
5 AZC
5-AC
s-Triazin-2(1H)-one, 4-amino-1-.beta.-D-ribofuranosyl-
NCI-C01569
arabinofuranosyl-5-azacytosine
Azacitidine;5-AzaC;Ladakamycin
1,3,5-Triazin-2(1H)-one, 4-amino-1-beta-D-ribofuranosyl-
?-Azacitidine
NSC 102816
CCRIS93; NSC 281272; Kymarabine
Vidaza (Pharmion)
Ara AC
4-amino-1-pentofuranosyl-1,3,5-triazin-2(1h)-one
Anitibiotic U 18496
4-Amino-1-.beta.-D-ribofuranosyl-s-triazin-2(1H)-one
Neuro_000048
Oprea1_630243
CHEMBL301216
SCHEMBL1249475
SCHEMBL20143987
DTXSID20859335
NMUSYJAQQFHJEW-UHFFFAOYSA-N
HMS3373H14
HMS3651G19
HGA77177
NSC281272
ZINC01078622
AKOS003382387
SB18981
NCGC00015046-02
NCGC00015046-03
NCGC00015046-04
NCGC00094964-01
NCGC00094964-02
NCGC00181113-01
NCI60_000078
NCI60_002288
SY023613
1-.beta.-D-Arabinofuranosyl-5-azacytosine
NS00123805
AB01273944-01
WLN: T6NVN ENJ DZ A- BT5OTJ CQ DQ E1Q
1,5-Triazin-2(1H)-one, 4-amino-1-.beta.-D-ribofuranosyl-
4-Amino-1-.beta.-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
1,5-Triazin-2(1H)-one, 4-amino-1-.beta.-D- arabinofuranosyl-
4-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,3,5-triazin-2(1H)-one