Interesting facts
Interesting Facts about 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
This compound is a fascinating instance of the intersection between organic chemistry and medicinal applications. A member of the pyrimidine family, it features several bioactive characteristics that contribute to its function in pharmacology. Here are some engaging points about this intriguing compound:
- Biological Role: The molecule plays a significant role in the synthesis of nucleotides, which are essential for RNA and DNA formation. This makes it pivotal in understanding cellular processes and genetic material.
- Structural Complexity: The compound contains a unique tetrahydrofuran ring, known for its role in carbohydrate chemistry. This sugar-like structure is also responsible for many interactions within biological systems, impacting enzyme activities.
- Potential Therapeutic Applications: Research has suggested its possible usage as an antiviral agent, particularly in the treatment of diseases caused by viral infections. The structural properties may enhance its affinity for viral targets.
- Stereochemistry Matters: The compound showcases chirality, with specific configurations that could influence its bioactivity. The R and S designations refer to the orientation of atoms in space, a factor critical in pharmacodynamics.
- Research Interest: Scientists are continuously exploring its derivatives to potentially enhance efficacy and reduce side effects. The ongoing studies highlight how small modifications in structure can lead to significant changes in behavior and activity.
In summary, 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one encapsulates both complexity and utility, making it a star compound in both organic synthesis and medicinal chemistry. As research evolves, its applications may expand further, offering new avenues for therapeutics.
Synonyms
cytidine
65-46-3
Cytosine riboside
1-beta-D-Ribofuranosylcytosine
4-Amino-1-beta-D-ribofuranosyl-2(1H)-pyrimidinone
1beta-Ribofuranosylcytosine
Cytidin
Zytidin
1-beta-Ribofuranosylcytosine
beta-D-Ribofuranoside, cytosine-1
1beta-D-Ribofuranosylcytosine
4-Amino-1beta-D-ribofuranosyl-2(1H)-pyrimidinone
Cytosine, 1-beta-D-ribofuranosyl-
1beta-2'-Ribofuranosylcytosine, d-
NSC 20258
cytosine-1beta-D-Ribofuranoside
CHEBI:17562
Cyd
EINECS 200-610-9
2(1H)-Pyrimidinone, 4-amino-1-beta-D-ribofuranosyl-
MFCD00006545
Posilent (TN)
5CSZ8459RP
2(1H)-Pyrimidinone, 4-amino-1beta-D-ribofuranosyl-
CYTIDINE [MI]
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
NSC-20258
CYTIDINE [MART.]
CYTIDINE [WHO-DD]
4-amino-1-beta-D-ribofuranosylpyrimidin-2(1H)-one
1.beta.-Ribofuranosylcytosine
1.beta.-D-Ribofuranosylcytosine
DTXSID60891552
.beta.-D-Ribofuranoside, cytosine-1
MMV638723
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
Cytosine, 1-.beta.-D-ribofuranosyl-
4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
C9H13N3O5
CYTIDINE (MART.)
4-Amino-1.beta.-D-ribofuranosyl-2(1H)-pyrimidinone
2(1H)-Pyrimidinone, 4-amino-1-.beta.-D-ribofuranosyl-
Cytidine; Cytarabine Impurity E
Riboside, Cytosine
CTN
SMR000058243
Cytosine Ribonucleoside
Ribonucleoside, Cytosine
UNII-5CSZ8459RP
Posilent
beta-cytidine
3h-cytidine
4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidin-2-one
4-amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-1,2-dihydropyrimidin-2-one
beta.-D-Ribo-C
Cytidine, 99%
CYTIDINE [INCI]
1-b-D-ribosyl-Cytosine
Cytosine beta-D-riboside
Cytosine-beta-D-riboside
1betaRibofuranosylcytosine
CP-C
1betaDRibofuranosylcytosine
bmse000190
bmse000969
bmse001020
Epitope ID:141494
SCHEMBL7179
1-b-D-Ribofuranosylcytosine
cytosine-1b-D-Ribofuranoside
beta-D-ribofuranosyl-cytidine
Cytosine, 1betaDribofuranosyl
MLS000049947
MLS002207040
1-beta-D-ribosyl- (6CI)
1-beta-delta-ribosyl-Cytosine
betaDRibofuranoside, cytosine1
CHEMBL95606
GTPL4728
1beta2'Ribofuranosylcytosine, d
1-beta-D-ribofuranosyl-Cytosine
cytosine-1b-delta-Ribofuranoside
SCHEMBL24781031
1-BETA-RIBOFURANOSYLOSINE
1beta-delta-Ribofuranosylcytosine
Cytosine-1-beta-D-ribofuranoside
1-beta-delta-Ribofuranosylcytosine
DTXCID901030645
Cytidine, >=99.0% (HPLC)
cytosine-1beta-delta-Ribofuranoside
1-beta-delta-ribofuranosyl-Cytosine
HY-B0158
CYTOSINE, 1-BETA-D-RIBOSYL-
s2053
AKOS015888568
CCG-266896
CS-1989
DB02097
NC04070
SRI-2352_17
NCGC00093356-08
NCGC00142483-01
NCGC00142483-09
AS-12696
BP-58628
4Amino1betaDribofuranosyl2(1H)pyrimidinone
DB-029614
NS00069068
2(1H)Pyrimidinone, 4amino1betaDribofuranosyl
C00475
D07769
EN300-184125
1-(beta-D-ribofuranosyl)-4-aminopyrimidin-2-one
4-Amino-1-b-D-ribofuranosyl-2(1H)-pyrimidinone
Cytosine -D-riboside;Cytosine-1--D-ribofuranoside
Q422538
BRD-K71847383-001-07-5
BRD-K71847383-001-12-5
4-Amino-1-.beta.-D-ribofuranosyl-2-(1H)-pyrimidinone
4-Amino-1-beta-delta-ribofuranosyl-2(1H)-pyrimidinone
F0348-2240
Z1879263740
1-(b-D-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine
6D2DC474-DD76-4081-8B34-10605C218F49
1-(b-delta-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine
1-(beta-D-Ribofuranosyl)-2-oxo-4-amino-1,2-dihydro-1,3-diazine
Cytidine, BioReagent, suitable for cell culture, powder, >=99%
200-610-9
Solubility of 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
The solubility of the compound 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one (C10H13N5O4) can be characterized by several important factors:
As a general observation, compounds similar to this structure often show improved solubility profiles due to the combined effects of their various functional groups. For instance:
In conclusion, the solubility of 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one is anticipated to be high in polar solvents, primarily due to its polar nature and the presence of multiple functional groups that favor interaction with solvent molecules. This could make it applicable in various aqueous environments. In the words of chemists, "Like dissolves like," which encapsulates the key principle of solubility in chemical compounds.