Interesting facts
Exploring 4-(8-methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline
This fascinating compound, often referred to for its unique structure and potential applications, brings together two significant chemical frameworks: the benzodiazepine and aniline moieties. Here are some intriguing aspects of this compound from a scientific perspective:
- Bioactive Potential: Compounds containing the benzodiazepine ring are well-known in medicinal chemistry for their psychoactive properties. This includes effects such as anxiolytic and sedative effects, making them valuable in pharmaceutical applications.
- Structural Diversity: The integration of a dioxole ring adds a level of complexity that can influence the compound's interactions with biological systems. Such structural elements are often associated with unique pharmacological profiles.
- Synthesis Challenges: The synthesis of this compound is not straightforward, given the presence of multiple functional groups and the need for precise control over reaction conditions. Mastering these techniques is crucial for chemists looking to manipulate the compound for research or medicinal purposes.
- Potential Research Applications: Researchers are continuously exploring compounds like this for their potential roles in treating various conditions, including anxiety disorders and other neuropsychiatric conditions, due to their structural similarities to known therapeutic agents.
- Analytical Techniques: Understanding and characterizing this compound may involve advanced analytical techniques, including NMR spectroscopy, mass spectrometry, and chromatography. These tools help in elucidating the structure and confirming the purity of the compound.
As a chemistry student or professional, delving into the properties and applications of compounds like 4-(8-methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline opens a window to the expansive world of organic chemistry and its implications in real-world applications. The blend of synthetic creativity and biological functionality exemplifies the beauty of chemical research!
Synonyms
Gyki-52466
102771-26-6
GYKI 52466
4-(8-methyl-9h-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline
4-(8-Methyl-9H-1,3-dioxolo(4,5-h)(2,3)benzodiazepin-5-yl)benzenamine
GYKI-2466
471V8NZ5X3
4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine
1-(p-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride
Benzenamine, 4-(8-methyl-9H-1,3-dioxolo(4,5-h)(2,3)benzodiazepin-5-yl)-
CHEMBL275006
CHEBI:79560
GYKI52466
DTXSID40145500
Benzenamine, 4-(8-methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-
4-(8-methyl-9H-[1,3]dioxolo[4',5':4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline
A1AB5
GYKI 52466 HCl
UNII-471V8NZ5X3
LFBZZHVSGAHQPP-UHFFFAOYSA-N
Tocris-1454
Lopac-G-119
Lopac0_000631
C17H15N3O2.HCl
SCHEMBL194854
GTPL4210
DTXCID8067991
GYKI53784
BCP02050
BDBM50048389
HB0311
PDSP1_001843
PDSP2_001826
AKOS030582785
BCP9000756
CCG-204719
SDCCGSBI-0050612.P002
NCGC00015463-01
NCGC00015463-02
NCGC00015463-03
NCGC00015463-04
NCGC00015463-08
NCGC00025169-01
NCGC00025169-02
DB-058860
HY-103234
CS-0025672
Q5515088
BRD-K24240364-003-02-1
BRD-K24240364-003-08-8
1-(4-aminophenyl)-4-methyl-7,8 -methylenedioxy-5H-2,3-benzodiazepine
4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine
4-(8-Methyl-9H-1,3-dioxa-6,7-diaza-cyclohepta[f]inden-5-yl)-phenylamine (GYKI 52466)
4-(8-methyl-9h-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-benzenamine hydrochloride
4-{13-METHYL-4,6-DIOXA-11,12-DIAZATRICYCLO[7.5.0.0(3),?]TETRADECA-1(9),2,7,10,12-PENTAEN-10-YL}ANILINE
4-{13-METHYL-4,6-DIOXA-11,12-DIAZATRICYCLO[7.5.0.0(3),?]TETRADECA-1,3(7),8,10,12-PENTAEN-10-YL}ANILINE
4-{13-methyl-4,6-dioxa-11,12-diazatricyclo[7.5.0.0^{3,7}]tetradeca-1(9),2,7,10,12-pentaen-10-yl}aniline
634-394-6
Solubility of 4-(8-methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline
The compound 4-(8-methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-5-yl)aniline, with the chemical formula C17H15ClN4O2, exhibits specific solubility characteristics that are significant for its applications in different fields. Generally, the solubility of organic compounds like this can be influenced by various factors:
In the case of this specific compound, the combination of the dioxole and benzodiazepine structures potentially leads to moderate solubility in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol. However, it may show limited solubility in water due to the hydrophobic regions inherent in its structure. As such, understanding its solubility profiles requires consideration of both:
Furthermore, while empirical data is crucial, computational modeling may also provide insights into the solubility behavior of this compound, helping to predict its performance in specific applications.