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DAB389EGF

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Identification
Molecular formula
C22H19N5O3S
CAS number
139599-52-1
IUPAC name
4-[(7-oxopyrrolo[2,3-g][1,3]benzothiazol-8-yl)methylamino]-N-(2-pyridyl)benzenesulfonamide
State
State

At room temperature, it is a solid with a crystalline appearance.

Melting point (Celsius)
212.00
Melting point (Kelvin)
485.15
Boiling point (Celsius)
365.00
Boiling point (Kelvin)
638.15
General information
Molecular weight
465.48g/mol
Molar mass
464.5450g/mol
Density
1.4800g/cm3
Appearence

The compound typically appears as a pale yellow to orange solid. It is sensitive to light and air, and should be stored in a tightly sealed container to prevent degradation.

Comment on solubility

Solubility of 4-[(7-oxopyrrolo[2,3-g][1,3]benzothiazol-8-yl)methylamino]-N-(2-pyridyl)benzenesulfonamide

The solubility of the compound C22H19N5O3S can be quite intriguing, given its complex structure. Various factors influence the solubility of such compounds, which can be summarized as follows:

  • Polarity: The presence of functional groups, such as sulfonamide and pyridyl, often enhances solubility in polar solvents.
  • Hydrogen Bonding: Compounds with capable hydrogen donor or acceptor sites tend to have increased solubility due to hydrogen bonding interactions.
  • Molecular Weight: The relatively high molecular weight can sometimes decrease solubility in organic solvents.
  • pH Dependence: The solubility may vary significantly with changes in pH, especially for compounds with acidic or basic functional groups.

It’s also important to note that when we assess solubility, we must consider the solvent system applied, as it can vastly impact the solubility profile. For example, polar aprotic solvents might solubilize the compound better than non-polar ones. Additionally, phase diagrams can provide insight into the solubility limits under varying temperatures and pressures.

In conclusion, while definitive solubility data for C22H19N5O3S might not always be readily available, understanding the factors outlined above can help predict its behavior in different environments. Thorough experimentation is crucial for determining its practical solubility in various conditions.

Interesting facts

Interesting Facts about 4-[(7-oxopyrrolo[2,3-g][1,3]benzothiazol-8-yl)methylamino]-N-(2-pyridyl)benzenesulfonamide

This intriguing compound belongs to the class of sulfonamides, which are known for their diverse biological activities and medicinal applications. Here are some remarkable features:

  • Biodiversity Potential: Sulfonamide derivatives are well-known in pharmacology for their antimicrobial properties. This specific compound may present unique interactions based on its complex structure.
  • Structural Complexity: The presence of multiple functional groups, including a pyrrolopyrrole and a benzene sulfonamide, indicates a potentially high level of biological specificity and activity.
  • Research Applications: Given its unique composition, this compound could be a subject of interest in medicinal chemistry, particularly in the development of new drugs targeting bacterial infections or cancer.

Mechanism of Action

While the precise mechanisms are still under investigation, compounds of this nature often work by inhibiting specific enzymes essential for bacterial growth, thereby displaying their antibacterial properties.

Current Research

Researchers are continually exploring the structure-activity relationships (SAR) of sulfonamides. Compounds like this one could lead to the discovery of drugs that overcome current antibiotic resistance challenges.

  • Effectiveness: Studies indicate that modifications in the molecular structure can enhance the activity against various pathogens.
  • Interdisciplinary Collaboration: The development and testing of such compounds often require cooperation between organic chemists, biochemists, and pharmacologists.

In summary, 4-[(7-oxopyrrolo[2,3-g][1,3]benzothiazol-8-yl)methylamino]-N-(2-pyridyl)benzenesulfonamide exemplifies the exciting possibilities within chemical research focused on sulfonamide compounds. Its intricate structure not only provides insights into its potential uses but also poses stimulating questions about new realms of medicinal chemistry.

Synonyms
4-[(7-oxo-7h-thiazolo[5,4-e]indol-8-ylmethyl)-amino]-n-pyridin-2-yl-benzenesulfonamide
1fvv
4-((7-Oxo-7H-thiazolo(5,4-E)indol-8-ylmethyl)-amino)-N-pyridin-2-YL-benzenesulfonamide
4-(((7-oxo-7H-(1,3)thiazolo(5,4-e)indol-8-yl)methyl)amino)-N-(pyridin-2-yl)benzene-1-sulfonamide
4-[({7-oxo-7h-[1,3]thiazolo[5,4-e]indol-8-yl}methyl)amino]-n-(pyridin-2-yl)benzene-1-sulfonamide
SCHEMBL13038800
DB06844
PD005868
NS00069468
Q27095748
4-{[(7-oxo-7H-[1,3]thiazolo[5,4-e]indol-8-yl)methyl]amino}-N-pyridin-2-ylbenzenesulfonamide