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4-(5-fluoro-2-hydroxyphenyl)thiobut-1-enylphosphonic acid

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Identification
Molecular formula
C10H12FO4P
CAS number
102212-25-3
IUPAC name
4-(5-fluoro-2-hydroxy-phenyl)sulfanylbut-1-enylphosphonic acid
State
State

At room temperature, 4-(5-fluoro-2-hydroxyphenyl)thiobut-1-enylphosphonic acid is stable as a solid. It can be stored for a period of time without significant degradation under proper conditions, which typically involve cool, dry environments.

Melting point (Celsius)
156.40
Melting point (Kelvin)
429.55
Boiling point (Celsius)
394.23
Boiling point (Kelvin)
667.38
General information
Molecular weight
256.22g/mol
Molar mass
256.2200g/mol
Density
1.4510g/cm3
Appearence

4-(5-fluoro-2-hydroxyphenyl)thiobut-1-enylphosphonic acid is typically a colorless to light tan powdered solid. Its appearance may vary slightly based on purity and form but generally maintains a uniform powder consistency suitable for research or industrial use.

Comment on solubility

Solubility of 4-(5-fluoro-2-hydroxy-phenyl)sulfanylbut-1-enylphosphonic acid (C10H12FO4P)

The solubility of 4-(5-fluoro-2-hydroxy-phenyl)sulfanylbut-1-enylphosphonic acid in various solvents plays a crucial role in its applications and efficacy. Several factors influence its solubility, including:

  • Polarity: Being a phosphonic acid, the presence of both polar and non-polar functional groups affects solubility in water and organic solvents.
  • Hydrogen Bonding: The hydroxyl group can engage in hydrogen bonding, potentially increasing solubility in polar solvents such as water.
  • Functional Groups: The presence of the fluorinated aromatic structure may introduce steric effects that can hinder solubility in specific media.

Generally, phosphonic acids tend to demonstrate better solubility in polar solvents compared to non-polar solvents. However, for this compound, specific solubility data may vary based on the conditions under which it is tested. According to some studies, phosphonic acids like this can exhibit:

  • High solubility in diluted acids
  • Moderate solubility in alcohols and acetone
  • Poor solubility in non-polar solvents like hydrocarbons

Overall, the solubility of 4-(5-fluoro-2-hydroxy-phenyl)sulfanylbut-1-enylphosphonic acid in water and other solvents is an essential consideration for its use in chemical reactions, formulations, and therapeutic applications. As with many compounds, understanding its solubility characteristics will greatly enhance its practical utilization.

Interesting facts

Exploring 4-(5-fluoro-2-hydroxy-phenyl)sulfanylbut-1-enylphosphonic acid

4-(5-fluoro-2-hydroxy-phenyl)sulfanylbut-1-enylphosphonic acid is a fascinating compound that showcases the intricate interplay between organic chemistry and medicinal applications. Here are some intriguing facts about this compound:

  • Functional Diversity: This compound features diverse functional groups, including a phosphonic acid moiety, which is known for its potential in biological systems and its use in drug development.
  • Fluorine's Role: The presence of a fluorine atom not only enhances the compound's lipophilicity but may also influence its biological activity, making it a subject of interest in pharmaceutical research.
  • Phenolic Hydroxy Group: The 2-hydroxy group on the aromatic ring contributes to the compound's potential as a ligand in complexation with metal ions, which is relevant in catalysis and various synthetic applications.
  • Applications in Medicine: Compounds with phosphonic acid groups are often explored for their antibacterial, antiviral, and anticancer properties. This positions 4-(5-fluoro-2-hydroxy-phenyl)sulfanylbut-1-enylphosphonic acid as a candidate for further investigation in drug discovery.
  • Molecular Geometry: The geometric arrangement of the compound's atoms can lead to different isomers, each potentially exhibiting unique properties, which is a key consideration in the design of pharmaceuticals.
  • Mechanistic Studies: Understanding the interactions and mechanisms of action of this compound can lend insights into the design of more effective therapies, particularly regarding phosphonate derivatives.

In summary, 4-(5-fluoro-2-hydroxy-phenyl)sulfanylbut-1-enylphosphonic acid is more than just a molecular entity; it represents a bridge between chemical synthesis and the quest for new therapeutic solutions. As research into its properties and applications advances, we may uncover even more exciting potential for this compound in various fields of science.

Synonyms
PD036614