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Folic Acid

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Identification
Molecular formula
C19H19N7O6
CAS number
59-30-3
IUPAC name
4-[[5-[5-[4-[(2-amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl)methylamino]phenyl]-2,3,4-trihydroxy-pentoxy]-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-4-[[1-(carboxymethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid
State
State

Folic Acid is a solid at room temperature. It is usually available in crystalline powder form and is known for its distinctive yellow or orange-yellow color.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
613.15
Boiling point (Kelvin)
886.30
General information
Molecular weight
441.40g/mol
Molar mass
441.4030g/mol
Density
1.3000g/cm3
Appearence

Folic Acid appears as a yellow or orange-yellow crystalline powder. It is weakly soluble in water and insoluble in alcohol, ether, and other organic solvents.

Comment on solubility

Solubility of 4-[[5-[5-[4-[(2-amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl)methylamino]phenyl]-2,3,4-trihydroxy-pentoxy]-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-4-[[1-(carboxymethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid

The solubility of complex organic compounds such as 4-[[5-[5-[4-[(2-amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl)methylamino]phenyl]-2,3,4-trihydroxy-pentoxy]-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-4-[[1-(carboxymethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid (C19H19N7O6) can vary significantly based on its chemical structure and functional groups. Here are some key factors to consider:

  • Polarity: The presence of numerous hydroxyl (-OH) and carboxyl (-COOH) groups suggests that this compound may exhibit increased hydrophilicity. This could enhance its solubility in polar solvents like water.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds with solvent molecules can further influence solubility. More potential hydrogen bonding sites can lead to higher solubility.
  • Aliphatic and Aromatic Structures: The balance of aliphatic chains and aromatic rings in the compound can affect its solubility. Aliphatic components can favor solubility in non-polar solvents, while aromatic sections may promote solubility in polar environments.
  • Molecular Interactions: The complex connectivity and presence of functional groups can lead to various intermolecular interactions, which may also affect solubility.

In conclusion, while the presence of hydroxyl and carboxyl groups indicates a potential for good solubility in polar solvents, the intricacies of molecular interactions play a critical role. Further empirical testing would be essential to determine the precise solubility characteristics in various solvents.

Interesting facts

Interesting Facts about 4-[[5-[5-[4-[(2-amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl)methylamino]phenyl]-2,3,4-trihydroxy-pentoxy]-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-4-[[1-(carboxymethyl)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid

This complex compound is a prime example of the intricate world of organic chemistry, embodying features that make it both fascinating and significant in various research fields. Below are some compelling aspects regarding this compound:

  • Pharmacological Potential: Compounds with similar structures often showcase potential bioactivity, making them of interest in pharmaceutical research, particularly in the development of antitumor and antimicrobial agents.
  • Structural Complexity: The presence of multiple functional groups, such as amino, hydroxy, and phosphoryl moieties, underscores the compound's potential for diverse chemical interactions.
  • Role in Biochemistry: This compound may play a critical role in biochemical pathways that involve nucleotide and amino acid metabolism, suggesting applications in both clinical diagnostics and therapeutic strategies.
  • Research Tool: The specific arrangements of phenyl and tetrahydrofuran units can serve as a useful template or scaffold in the design of novel bioactive molecules.
  • Multifunctionality: With the capacity to engage different biological targets, this compound can be optimized to create agents that tackle various diseases, illustrating the trend of multifunctional small molecules in modern drug design.

Given its structural attributes and potential applications, this compound stands at the forefront of research endeavors aimed at harnessing the beauty of chemistry for improving human health and understanding biological systems.