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VX-765

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Identification
Molecular formula
C16H15F3N4
CAS number
273404-37-8
IUPAC name
4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline
State
State

This compound is typically found as a solid at room temperature.

Melting point (Celsius)
221.00
Melting point (Kelvin)
494.00
Boiling point (Celsius)
538.50
Boiling point (Kelvin)
811.50
General information
Molecular weight
321.33g/mol
Molar mass
321.3290g/mol
Density
1.3840g/cm3
Appearence

This compound typically appears as a white to off-white solid powder.

Comment on solubility

Solubility of 4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline

The compound 4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline (C16H15F3N4) exhibits interesting solubility characteristics that merit attention. This compound is characterized by its unique structure which directly influences its interaction with solvents.

Factors Affecting Solubility:

  • Polarity: The presence of the trifluoromethyl group tends to increase polarity, allowing for potential solubility in polar solvents.
  • Hydrophilicity vs. Hydrophobicity: The alkyl and aromatic groups contribute to hydrophobic character, suggesting lower solubility in water.
  • Temperature: Solubility can also be affected by temperature; many compounds demonstrate increased solubility at elevated temperatures.

Given the above factors, one might find that:

  • The compound is likely to be more soluble in organic solvents such as dimethyl sulfoxide (DMSO) or ethanol.
  • Its solubility in water is relatively low according to its hydrophobic characteristics.
  • In practical applications, increased solubility could be pivotal for drug formulation or synthesis.

In conclusion, understanding the solubility behavior of this compound is essential for its effective application in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline

4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline is a fascinating compound that has drawn attention in both pharmaceutical and chemical research fields. Here are some intriguing aspects of this compound:

  • Structure and Function: This compound features a complex molecular structure that combines a pyrrolo[1,2-a]quinoxaline core with a trifluoromethyl group and a piperazine moiety. This unique arrangement may contribute to its potential bioactivity.
  • Applications: The presence of the trifluoromethyl group often enhances the lipophilicity and metabolic stability of compounds, making them more effective in biological systems. This may position the compound as a candidate for drug development, especially in targeting central nervous system disorders.
  • Research Significance: Due to its structural complexity, compounds like this one serve as important tools in medicinal chemistry for studying structure-activity relationships (SAR). Researchers can modify various functional groups to examine how those changes affect the compound’s efficacy and safety.
  • Potential Therapeutic Roles: Compounds with piperazine rings are frequently investigated for their roles as anxiolytics, antipsychotics, or antidepressants. This compound's configuration suggests it could intercept important pathways in neurotransmitter modulation.
  • Fluorine Chemistry: The trifluoromethyl group is notable in modern chemistry, as it imparts unique electronic properties to molecules. This can lead to enhanced interactions within biological targets, making fluorinated compounds especially intriguing in drug design.

In conclusion, 4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline showcases the intricate relationship between molecular structure and biological activity. As research continues, this compound could shed light on new therapeutic strategies and the design of innovative drugs.

Synonyms
109028-09-3
4-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline
CGS 12066B-parent
CGS 12066B
Cgs 12066
CGS-12066
CGS12066
5TB4SXQ7HG
CHEMBL27403
CHEBI:64055
7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt
Pyrrolo(1,2-a)quinoxaline, 4-(4-methyl-1-piperazinyl)-7-(trifluoromethyl)-
Pyrrolo[1,2-a]quinoxaline, 4-(4-methyl-1-piperazinyl)-7-(trifluoromethyl)-
UNII-5TB4SXQ7HG
CGS-12066A
NCGC00024701-01
Tocris-0638
Lopac-C-106
Biomol-NT_000089
Lopac0_000332
GTPL109
BPBio1_001091
SCHEMBL1660466
DTXSID3043730
BDBM81497
CCG-204427
NSC_123945
SDCCGSBI-0050320.P002
NCGC00015180-01
NCGC00015180-02
NCGC00015180-03
NCGC00015180-04
NCGC00015180-05
NCGC00015180-10
NCGC00024701-02
NCGC00024701-03
BS-47553
J336.559J
CAS_109028-10-6
CS-0162537
E75105
L000723
Q5010989
BRD-K18909381-001-01-4
4-(4-Methyl-1-piperazinyl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline
4-(4-Methyl-1-piperazinyl)-7-(trifluoromethyl)pyrrolo[1,2-a]quinoxaline #
4-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-pyrrolo[1,2-a]quinoxaline
7-trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]quinoxaline
4-(4-METHYL-1-PIPERAZINYL)-7-(TRIFLUOROMETHYL)-PYRROLO[1,2-A]QUINOXALINE
7-(TRIFLUOROMETHYL)-4-(4-METHYLPIPERAZIN-1-YL)PYRROLO(1,2-A)QUINOXALINE