Interesting facts
Interesting Facts about [4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)piperazin-1-yl]-tetrahydrofuran-2-yl-methanone
This compound is a fascinating example of a complex organic molecule, showcasing the intricate connections between various chemical structures. Here are some notable aspects:
- Quinazolin Derivative: This compound features a quinazolin ring, which is well known for its biological activity, particularly in medicinal chemistry. Compounds with this structure can serve as potential therapeutic agents.
- Piperazine Moiety: The presence of a piperazine ring contributes to the compound's ability to interact with biological systems. Piperazines are often found in pharmaceuticals for their effects on the central nervous system.
- Dimethoxy Substituents: The two methoxy groups on the quinazolin ring enhance the compound's lipophilicity, potentially improving its ability to penetrate cell membranes, which is a critical factor in drug design.
- Therapeutic Potential: Compounds like this one are studied for their potential applications in treating various conditions due to their unique structural properties and biological activity.
As stated by researchers in the field, “The exploration of quinazolin derivatives offers a promising path towards novel therapeutic developments.” This highlights the significance of such chemical compounds in ongoing medical research and development.
In terms of synthesis, creating this compound involves multiple steps, including condensation and functionalization reactions that require precision and a careful approach to handle the reactivity of various groups.
Finally, understanding the interactions at play within this compound can lead to insights into how it may function biologically, paving the way for future studies and applications in pharmaceuticals.
Synonyms
terazosin
63590-64-7
Terazosine
Fosfomic
Terazosina
Blavin
Flumarc
Vasomet
Terazosinum
Hytrin
Terazosabb
Terazosine [INN-French]
Terazosinum [INN-Latin]
Terazosina [INN-Spanish]
terazocin
141269-45-6
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine
Terazosin (INN)
UNII-8L5014XET7
CHEBI:9445
8L5014XET7
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone
141269-44-5
CHEMBL611
6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]quinazolin-4-amine
MLS000069703
Terazosin (hydrochloride)
DTXSID3023639
6,7-Dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine hydrochloride
SMR000058309
TERAZOSIN [INN]
Terazosine (INN-French)
Terazosinum (INN-Latin)
Terazosin [INN:BAN]
Terazosina (INN-Spanish)
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(tetrahydro-2-furoyl)piperazine
(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone
6,7-dimethoxy-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)-
Abbott 45975
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl](tetrahydrofuran-2-yl)methanone
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-{(tetnaphydro-2-furanyl)carbonyl}piperazine
Terazosabb (TN)
MFCD00467965
C19H25N5O4
terazosin a
6,7-dimethoxy-2-(4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl)quinazolin-4-amine
TERAZOSIN [MI]
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)4-[(tetrahydro-2-furanyl)carbonyl]piperazine hydrochloride
Opera_ID_1910
Prestwick0_000751
Prestwick1_000751
Prestwick2_000751
Prestwick3_000751
TERAZOSIN [VANDF]
SCHEMBL6528
TERAZOSIN [WHO-DD]
Lopac0_001138
REGID_for_CID_5401
BSPBio_000762
MLS001201836
MLS006011889
SPBio_002701
BPBio1_000840
DTXCID003639
GTPL7302
G04CA03
HMS2090P21
HMS2232N21
HMS3259F04
HMS3369P14
HMS3371E20
HMS3742I09
HY-B0371
JEA35134
BBL010743
BDBM50033111
STK567029
AKOS005266642
CCG-205212
DB01162
FA28036
NC00689
SDCCGSBI-0051105.P002
6,7-bis(methyloxy)-2-[4-(tetrahydrofuran-2-ylcarbonyl)piperazin-1-yl]quinazolin-4-amine
NCGC00016026-04
NCGC00016026-05
NCGC00016026-08
NCGC00016026-11
NCGC00025191-03
AC-11120
LS-14728
NS00008855
C07127
D08569
EN300-119614
G77833
L000692
Q280786
BRD-A22256192-003-03-7
BRD-A22256192-003-14-4
BRD-A22256192-003-22-7
BRD-A22256192-310-02-8
Z1172269406
Terazosin hydrochloride;Adecur;Apo-Terazosin;Deflox;Dysalfa;Flotrin
1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine
1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)-piperazine
6,7-dimethoxy-2-[4-(oxolane-2-carbonyl)piperazin-1-yl]-3,4-dihydroquinazolin-4-imine
6,7-Dimethoxy-2-[4-(tetrahydro-2-furanylcarbonyl)-1-piperazinyl]-4-quinazolinamine #
6,7-dimethoxy-2-{4-[(oxolan-2-yl)carbonyl]piperazin-1-yl}quinazolin-4-amine
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonxyl]piperazine Hydrochloride
1-(4-amino-6,7-dimethoxyquinazolin-2-yl)-4-[[(2RS)-2,3,4,5-tetrahydrofuran-2-yl]carbonyl]piperazine
Solubility of [4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)piperazin-1-yl]-tetrahydrofuran-2-yl-methanone
The solubility of the compound with the chemical formula C19H27N5O4 can provide critical insights into its potential applications and behavior in various solvents. This compound features a complex structure characterized by multiple functional groups, which significantly influence its solubility.
Key Factors Affecting Solubility:
Thus, the solubility of this compound is expected to be:
In conclusion, understanding the solubility profile of [4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)piperazin-1-yl]-tetrahydrofuran-2-yl-methanone is crucial for its optimal use in pharmaceutical formulations and other chemical applications. Testing under various environmental conditions will further elucidate its compatibility with different media.