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Prazosin

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Identification
Molecular formula
C19H21N5O4
CAS number
19216-56-9
IUPAC name
[4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2-furyl)methanone
State
State

Prazosin, at room temperature, is a solid crystalline substance. Due to its stable crystalline form, it remains unchanged under standard conditions, which makes it suitable for storage and handling in typical laboratory and manufacturing environments.

Melting point (Celsius)
284.00
Melting point (Kelvin)
557.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
383.42g/mol
Molar mass
383.4230g/mol
Density
1.3173g/cm3
Appearence

Prazosin hydrochloride appears as a white to off-white crystalline powder. It is odorless and has a bitter taste. The compound exhibits a slight solubility in water, making it convenient for pharmaceutical preparations.

Comment on solubility

Solubility of [4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2-furyl)methanone (C19H21N5O4)

The solubility of a compound in solvents greatly influences its applications in various fields, including pharmaceuticals and material sciences. For the compound [4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2-furyl)methanone, the solubility characteristics can be summarized as follows:

  • Polarity: Given its diverse functional groups, including amines and methoxy groups, the compound may exhibit considerable polarity which generally favors solubility in polar solvents.
  • Solvent Compatibility: It is likely to be soluble in water to some extent but may demonstrate better solubility in organic solvents like DMSO or ethanol, which can accommodate the complex structure.
  • Temperature Effects: As with many organic compounds, increased temperature can enhance solubility, allowing more of the compound to dissolve.
  • pH Influence: The solubility may vary with pH, particularly due to the amino group that can be protonated in acidic conditions, potentially increasing solubility.

In conclusion, while the solubility of [4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2-furyl)methanone can be positively influenced by factors such as solvent choice and temperature, empirical studies are essential to determine its precise solubility profiles accurately. Emphasizing the importance of these parameters is crucial for applications such as drug formulation and processing efficiency.

Interesting facts

Interesting Facts About 4-(4-amino-6,7-dimethoxy-quinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl-(2-furyl)methanone

This fascinating compound has piqued the interest of chemists due to its complex structure and potential biological applications. Below are some noteworthy aspects:

  • Structural Diversity: This compound exhibits a rich variety of functional groups, including amino, methoxy, and furan moieties. Such diversity often leads to unique chemical behaviors and reactivity.
  • Pharmacological Potential: Compounds with quinazolin and quinoxaline frameworks are known for their diverse therapeutic properties. Research suggests that similar structures may exhibit anti-cancer, anti-inflammatory, and anti-microbial activities.
  • Synthetic Challenges: The synthesis of this compound may require multiple steps and careful handling of reactive intermediates. Chemists often face intriguing challenges in optimizing yield and purity.
  • Interdisciplinary Interest: This type of compound not only captivates chemists but also pharmacologists and biochemists, showcasing the intersection of different scientific domains in drug discovery.
  • Research Opportunities: The exploration of this compound could open avenues for the development of new therapeutic agents, making it a subject of ongoing research in medicinal chemistry.

As scientists continue to explore compounds like this, they often find themselves quoting the famous phrase: "Innovation arises from the interplay of creativity and scientific inquiry." With its intricate structure, this compound exemplifies how chemistry is continuously evolving, leading to discoveries that might one day transform medicine and technology.

Synonyms
CHEMBL97698
[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(2-furanyl)methanone
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-(furan-2-yl)methanone
CHEBI:94370
DTXSID50861385
BDBM50122826
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)octahydroquinoxalin-1(2H)-yl](furan-2-yl)methanone
NCGC00485075-01
L001338
BRD-A37837077-003-01-1
Q27166211
[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-octahydro-quinoxalin-1-yl]-furan-2-yl-methanone
(Cyclazosin)[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-octahydro-quinoxalin-1-yl]-furan-2-yl-methanone