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Acetaminophen phenyl acetate

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Identification
Molecular formula
C20H17NO4
CAS number
26252-09-7
IUPAC name
[4-[(4-acetoxyphenyl)-(2-pyridyl)methyl]phenyl] acetate
State
State

At room temperature, this compound is found in a solid state. It is stable under standard conditions and does not dissolve easily in water but may be soluble in some organic solvents.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
482.15
Boiling point (Kelvin)
755.30
General information
Molecular weight
298.32g/mol
Molar mass
298.3160g/mol
Density
1.1830g/cm3
Appearence

This compound typically appears as an off-white to yellow crystalline powder. Its appearance can vary slightly depending on its purity and the presence of any impurities.

Comment on solubility

Solubility of [4-[(4-acetoxyphenyl)-(2-pyridyl)methyl]phenyl] acetate (C20H17NO4)

The compound [4-[(4-acetoxyphenyl)-(2-pyridyl)methyl]phenyl] acetate exhibits interesting solubility characteristics that merit attention. Here are some key points regarding its solubility:

  • Solvent Polarity: This compound is expected to exhibit varying solubility in solvents of different polarities due to the presence of functional groups like the acetoxy and pyridyl moiety.
  • Solubility in Organic Solvents: It is typically soluble in organic solvents such as ethanol, methanol, and dichloromethane, owing to its non-polar aromatic structure and polar functional groups.
  • Limited Water Solubility: Due to its relatively large non-polar segments, [4-[(4-acetoxyphenyl)-(2-pyridyl)methyl]phenyl] acetate is likely to have limited solubility in water. This is a common trait among many aromatic compounds.
  • Temperature Dependence: As with many organic compounds, solubility can increase with temperature. Thus, heating the solvent may facilitate better dissolution.
  • pH Influence: The solubility may also be affected by the pH of the solvent, especially if the functional groups can ionize or interact with acidic or basic media.

In summary, while [4-[(4-acetoxyphenyl)-(2-pyridyl)methyl]phenyl] acetate is soluble in a range of organic solvents, its water solubility is significantly limited, showcasing the influence of molecular structure on solubility behavior.

Interesting facts

Interesting Facts about 4-[(4-acetoxyphenyl)-(2-pyridyl)methyl]phenyl acetate

The compound 4-[(4-acetoxyphenyl)-(2-pyridyl)methyl]phenyl acetate, a unique hybrid molecule, combines functional groups that are significant in medicinal chemistry and material sciences. Here are some fascinating aspects of this compound:

  • Structural Significance: This compound features a complex structure that includes both aromatic and heterocyclic rings, contributing to its potential biological activity.
  • Acetoxy Group: The presence of the acetoxy group enhances the lipophilicity of the compound, which can affect its permeability and absorption in biological systems.
  • Pyridine's Influence: The inclusion of the pyridyl moiety is intriguing since pyridine derivatives are often explored for their role in pharmaceuticals, potentially exhibiting activities such as antibacterial, antifungal, and anticancer properties.
  • Research Applications: Utilizing a compound like this in research can lead to the development of new drugs or therapeutic agents, as the interaction of the various functional groups can create unique modes of action.
  • Synthetic Interest: This compound can be synthesized through multiple synthetic routes that involve standard organic transformations, highlighting its potential as a model for teaching organic synthesis techniques.

This compound exemplifies the exciting interplay between organic chemistry and pharmacology, where tailored functionalities can yield novel compounds with desirable biological activities. As researchers continue to explore such molecules, the potential for innovation remains vast, signifying the importance of studying complex chemical structures.

Synonyms
bisacodyl
603-50-9
Dulcolax
Bicol
Theralax
Sk-bisacodyl
Brocalax
Durolax
Fenilaxan
Sanvacual
Bisacodilo
Dulcolan
Endokolat
Hillcolax
Stadalax
Eulaxan
Godalax
Ivilax
Laxadin
Laxans
Laxine
Laxorex
Neolax
Nigalax
Pyrilax
Telemin
Zetrax
Laxanin N
Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester)
Bisacodylum
LACO
Modane
Evac-Q-Tabs
LA96a
(Pyridin-2-ylmethylene)bis(4,1-phenylene) diacetate
Feen-a-Mint Tablets
Correctol Tablets, Caplets
4,4'-(2-Pyridylmethylene)diphenol diacetate (ester)
Bis(p-acetoxyphenyl)-2-pyridylmethane
Di-(p-acetoxyphenyl)-2-pyridylmethane
Di-(4-acetoxyphenyl)-2-pyridylmethane
NSC-755914
MLS000069729
DTXSID1022681
2-(4,4'-Diacetoxydiphenylmethyl)pyridine
(4,4'-Diacetoxydiphenyl)(2-pyridyl)methane
4,4'-(2-Pyridylmethylene)diphenol diacetate
Phenol, 4,4'-(2-pyridylmethylene)di-, diacetate (ester)
MFCD00038039
10X0709Y6I
4,4'-Diacetoxydiphenylpyridyl-2-methane
SMR000058226
MLS002701749
DTXCID202681
Ulcolax
4,4'-(2-pyridylmethylene)bisphenol diacetate
HALFLYTELY COMPONENT BISACODYL
NSC614826
4,4'-Diacetoxydiphenylpyrid-2-ylmethane
NCGC00016522-05
NCGC00016522-10
4-{[4-(acetyloxy)phenyl](pyridin-2-yl)methyl}phenyl acetate
Bisacodyl 100 microg/mL in Acetonitrile
CAS-603-50-9
Deficol
Phenol, 4,4'-(2-pyridinylmethylene)bis-, 1,1'-diacetate
BISACODYL (MART.)
BISACODYL [MART.]
BISACODYL (USP-RS)
BISACODYL [USP-RS]
BISACODYL (EP MONOGRAPH)
BISACODYL [EP MONOGRAPH]
4,4'-(pyridin-2-ylmethylene)bis(4,1-phenylene) diacetate
BISACODYL (USP MONOGRAPH)
BISACODYL [USP MONOGRAPH]
Broxalax
HalfLytely
Bisacodylum [INN-Latin]
Bisacodilo [INN-Spanish]
HSDB 3016
(pyridin-2-ylmethylene)di-4,1-phenylene diacetate
SR-01000000233
[4-[(4-acetyloxyphenyl)-pyridin-2-ylmethyl]phenyl] acetate
EINECS 210-044-4
bisacodil
BRN 0323727
Bisacodyle
Bisacody
LaxativeGentle
Conlax
Horton
LaxativeWomen
BIisacodyl
Womans Laxative
Womens Laxative
CCRIS 8864
Publix Women
Bisacodyl 5mg
C-lax Laxative
UNII-10X0709Y6I
Dulcolax Laxative
Bisacodyl [USP:INN:BAN:JAN]
Bisacodyl 5 mg
The Magic Bullet
Bisacodyl Laxative
OneLAX
Bisacodyl,(S)
Laxative for Women
Dulcolax (TN)
Prestwick_780
Cvs Gentle Laxative
Publix WomenLaxative
Unit Dose Bisacodyl
Bisacodyl Suppository
Stratuscare Bisacodyl
BISCODYL
Carters Little Pills
HEB Gentle Laxative
P Lax Dr
Y Lax Dr
Bisacodyl (Standard)
BisacodyEnteric Coated
Extra Gentle Laxative
LaxativeEnteric Coated
Rugby Gentle Laxative
Leader Gentle Laxative
Leader Womens Laxative
Meijer Gentle Laxative
Womens Gentle Laxative
BisacodylEnteric Coated
Avedana Gentle Laxative
Spectrum_000086
PublixStimulant Laxative
BISACODYL ENTERIC
HalfLytely (Salt/Mix)
TopCare Gentle Laxative
BET-R-PREP Bisacodyl
BISACODYL [INN]
BISACODYL [JAN]
Opera_ID_884
BISACODYL [MI]
BISACODYL [HSDB]
Gentle Laxative Bisacodyl
Gentle Overnight Laxative
Prestwick0_000419
Prestwick1_000419
Prestwick2_000419
Prestwick3_000419
Simpex Bisacodyl Laxative
Spectrum2_000149
Spectrum3_000318
Spectrum4_000256
Spectrum5_000898
Walgreens Gentle Laxative
BISACODYL [VANDF]
up and up gentle laxative
BisacodylStimulant Laxative
Dulcolax Simulant Laxative
HealthMart Gentle Laxative
CHEMBL942
Dulcolax Stimulant Laxative
NCIChal_000004
NCIMech_000456
BISACODYL [WHO-DD]
cid_2391
REGID_for_CID_2391
SCHEMBL21044
BSPBio_000378
BSPBio_001916
KBioGR_000692
KBioSS_000506
DivK1c_000347
Rite Aid fast relief laxative
SPECTRUM1500147
Best Choice Bisacodyl Laxative
Dollar General Gentle Laxative
SPBio_000258
SPBio_002317
Bisacodyl (JP17/USP/INN)
BPBio1_000416
CHEBI:3125
BISACODYL [ORANGE BOOK]
Bisacodyl for system suitability
Bisacodyl LaxativeEnteric Coated
Carters Little PillsSodium-Free
Dulcolax Pink Stimulant Laxative
Medique Medi-lax Enteric Coated
Premier Value Bisacodyl Laxative
BDBM61400
Bisacodyl for peak identification
Gentle LaxativeStimulant Laxative
HMS501B09
HY-B0557R
KBio1_000347
KBio2_000506
KBio2_003074
KBio2_005642
KBio3_001416
A06AB02
A06AG02
Discount Drugmart Gentle Laxative
Enteric Coated Stimulant Laxative
Stimulant Laxative Enteric Coated
Foster and Thrive Gentle Laxative
NINDS_000347
HMS1569C20
HMS1920G21
HMS2090K15
HMS2091O03
HMS2096C20
HMS2235I11
HMS3373L17
HMS3652E04
HMS3713C20
Pharmakon1600-01500147
BCP18567
HY-B0557
The Medicine Shoppe Gentle Laxative
Tox21_110472
Tox21_200338
CCG-35661
CCG-36442
NSC755914
s4047
STK293202
WOMENS LAXATIVE ENTERIC COATED
AKOS001599884
Good Neighbor Pharmacy Gentle Laxative
Tox21_110472_1
BISAC-10 Bisacodyl Stimulant Laxative
DB09020
FB18804
NSC 755914
NSC-614826
BISACODYL COMPONENT OF HALFLYTELY
IDI1_000347
Bisacodyl, active ingredient of Viraplex
DELAYED RELEASE LAXATIVE BISACODYL
NCGC00016522-01
NCGC00016522-02
NCGC00016522-03
NCGC00016522-04
NCGC00016522-06
NCGC00016522-07
NCGC00016522-08
NCGC00016522-09
NCGC00016522-11
NCGC00016522-12
NCGC00023260-03
NCGC00023260-04
NCGC00023260-05
NCGC00023260-06
NCGC00257892-01
AC-24284
AS-15820
NCI60_004954
SBI-0051297.P003
AB00051928
B5066
NS00006175
SW196918-3
D00245
D81813
AB00051928-17
AB00051928_18
AB00051928_19
Bisacodyl, analytical standard, for drug analysis
EN300-7405275
Phenol, 4,4'-(2-pyridylmethylene)di-, diacetate
Q417874
4,4'-(Pyridin-2-ylmethylene)bis(phenyl acetate)
SR-01000000233-2
SR-01000000233-3
(pyridin-2-ylmethanediyl)dibenzene-4,1-diyl diacetate
BRD-K39987650-001-05-0
BRD-K39987650-001-15-9
BRD-K39987650-001-23-3
BRD-K39987650-001-24-1
Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate
Phenol,4'-(2-pyridinylmethylene)bis-, diacetate (ester)
Bisacodyl, European Pharmacopoeia (EP) Reference Standard
4-[[4-(Acetyloxy)phenyl](2-pyridinyl)methyl]phenyl acetate #
Bisacodyl, United States Pharmacopeia (USP) Reference Standard
Bisacodyl for peak identification, European Pharmacopoeia (EP) Reference Standard
Bisacodyl for system suitability, European Pharmacopoeia (EP) Reference Standard
210-044-4