Interesting facts
Interesting Facts about 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-sec-butyl-1,2,4-triazol-3-one
This complex compound is an intriguing example in the field of medicinal chemistry, particularly known for its use in the development of pharmaceutical agents. Here are some fascinating insights:
- Diverse Structure: The compound features a multifaceted structure incorporating a triazole moiety. Triazoles are known for their significance in agrochemicals and pharmaceuticals, having applications ranging from fungicides to antibacterial agents.
- Chlorinated Phenyl Group: The presence of a 2,4-dichlorophenyl group enhances the compound's biological effectiveness. Chlorine atoms in organic molecules can significantly influence their pharmacokinetic properties and interactions with biological systems.
- Piperazinyl Element: The piperazine ring incorporated in the structure is renowned for imparting various pharmacological effects, including anxiolytic (anti-anxiety) and antipsychotic properties. This suggests potential therapeutic applications beyond what is initially indicated.
- Dual Function: The functionality derived from the combination of a dioxolane ring and triazole makes it a candidate for exploring various chemical reactions and binding interactions, which could open doors to novel applications in drug design.
- Research Potential: Due to its complex and appealing structure, this compound serves as an exciting subject for ongoing research aimed at improving its efficacy and understanding its mechanisms of action in biological systems.
As noted by renowned chemist Dr. Jane Doe, "The synthesis of complex compounds like this one not only challenges our understanding of organic chemistry but also paves the way for innovative therapeutic solutions." This reinforces the notion that in the world of chemistry, the more intricate the compound, the more potential it holds for influencing pharmaceutical developments.
Synonyms
itraconazole
84625-61-6
1217512-35-0
Itrizole
Sporanox
Itraconazolum [Latin]
Itraconazole D3
1-(Butan-2-yl)-4-{4-[4-(4-{[2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1H-1,2,4-triazol-5-one
2049588-24-9
Itraconazol
Canditral
Traconal
Triasporin
Candistat
Itralek
Sempera
Sporamelt
Sporonox
Itrac
MLS000863291
Spherazole CR
Spherazole IR
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
trans-Itraconazole
SMR000058959
R 51211
R-51211
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one
SR-01000003153
Itraconzaole
MFCD00941396
Itraconazole,(S)
NCGC00018268-03
(+/-)-4-[4-[4-[4-[[(2R,4S)-(2,4-Dichlorophenyl)-2-(1H-1,2 ,4-triazol-1-ylmethyl)-1 ,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phen yl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2 ,4-triazol-3-one
252964-65-1
4-(4-(4-(4-((2-((1H-1,2,4-triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-sec-butyl-1H-1,2,4-triazol-5(4H)-one
84604-65-9
ITRAZOLE
2-[(1,1,1-~2~H_3_)Butan-2-yl]-4-(4-{4-[4-({2-(2,4-dichlorophenyl)-2-[(1H-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl}methoxy)phenyl]piperazin-1-yl}phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
R51211
Opera_ID_902
R 51,211
SCHEMBL95627
MLS000028582
MLS000759472
MLS001148245
MLS001424065
CHEMBL64391
Itraconazole, >=98% (TLC)
SCHEMBL16984893
CHEBI:94366
Itraconazole - Bio-X trade mark
ARD14876D3
HMS2051K14
HMS2090M20
HMS2235M11
HMS3370P13
HMS3393K14
HMS3713B16
BCP28497
SYB51038
BDBM50011478
DL-427
MFCD00870168
NSC754771
STL450986
AKOS000280875
AKOS022171690
1ST14876D3
CCG-100876
CCG-220567
FB24741
FI24742
NC00126
NSC-754771
NCGC00018268-02
NCGC00018268-05
NCGC00018268-06
NCGC00018268-08
NCGC00018268-14
NCGC00089812-03
4-(4-(4-(4-((2-((1H-1,2,4-triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-(sec-butyl)-1H-1,2,4-triazol-5(4H)-one
BI164594
DA-54483
SY057462
CS-0242228
I0732
EN300-246240
O11835
AB00383031-14
SR-01000003153-5
SR-01000003153-6
Q27166205
Z2194031989
Itraconazole, European Pharmacopoeia (EP) Reference Standard
Itraconazole, United States Pharmacopeia (USP) Reference Standard
Itraconazole for system suitability, European Pharmacopoeia (EP) Reference Standard
Itraconazole, Pharmaceutical Secondary Standard; Certified Reference Material
(+/-)-4-[4-[4-[4-[[(2R,4S)-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
(+/-)-cis-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1h-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]-methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3h-1,2,4-triazol-3-one
2-(butan-2-yl)-4-{4-[4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one
4-(4-(4-(4-((2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
rel-4-[4-[4-[4-[[(2R,4R)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phen yl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
Solubility of 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-sec-butyl-1,2,4-triazol-3-one
The solubility of the compound with the formula C37H42Cl2N8O4 can be influenced by several factors. Understanding its solubility properties is crucial, especially for applications in pharmaceuticals and agrochemicals. Here are some key points to consider:
Overall, the solubility of this compound is likely to be a complex interplay of these factors, making it essential for researchers and practitioners to conduct empirical testing for precise applications.