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4-[4-[(2-oxoindolin-3-ylidene)methyl]phenyl]piperazine-1-carbaldehyde

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Identification
Molecular formula
C20H19N3O2
CAS number
873745-34-3
IUPAC name
4-[4-[(2-oxoindolin-3-ylidene)methyl]phenyl]piperazine-1-carbaldehyde
State
State

Solid: At room temperature, this compound is found in a solid state. It is stable and does not readily evaporate.

Melting point (Celsius)
282.00
Melting point (Kelvin)
555.00
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.00
General information
Molecular weight
335.38g/mol
Molar mass
335.3840g/mol
Density
1.2750g/cm3
Appearence

The compound appears as a yellow to orange crystalline powder. Its vibrant color indicates strong light absorption typical for extended conjugated systems present in its structure.

Comment on solubility

Solubility of 4-[4-[(2-oxoindolin-3-ylidene)methyl]phenyl]piperazine-1-carbaldehyde

The solubility of the compound with the formula C20H19N3O2 can be quite intriguing given its complex structure and functional groups. Solubility is primarily influenced by the molecular interactions and the polarity of the compound, as well as the nature of the solvent.

Factors Affecting Solubility:

  • Polarity: The presence of amine (piperazine) and carbonyl (aldehyde) groups may enhance solubility in polar solvents like water, while hydrophobic aromatic rings could limit solubility in highly polar environments.
  • Hydrogen Bonding: The ability to form hydrogen bonds can increase solubility in polar solvents, which is likely due to both the aldehyde and amino groups present.
  • Solvent Type: A solvent's polarity will significantly affect how well this compound dissolves. It may be more soluble in organic solvents (e.g., ethanol, methanol) compared to water.

As a general observation, compounds similar to 4-[4-[(2-oxoindolin-3-ylidene)methyl]phenyl]piperazine-1-carbaldehyde often show moderate solubility across a range of organic solvents, with lesser solubility in water. It’s important to note that experimental solubility data is vital for precise understanding as theoretical predictions cannot account for all interactions.

In summary, the solubility characteristics of this compound reveal that:

  • It may have variable solubility depending on the solvent used.
  • Its complex structure can lead to unique solubility behaviors.

Therefore, direct experimentation would be essential to establish conclusive solubility profiles for practical applications.

Interesting facts

Interesting Facts about 4-[4-[(2-oxoindolin-3-ylidene)methyl]phenyl]piperazine-1-carbaldehyde

This compound, known as a modern pharmaceutical intermediate, is attracting interest for its potential applications in medicinal chemistry. Here are some noteworthy aspects of this fascinating molecule:

  • Structure & Function: The unique structure of this compound features a piperazine ring linked to an aldehyde and an oxoindole moiety, making it a prime candidate for bioactive investigations, especially in the field of neuroscience.
  • Bioactivity: Due to its multifunctional nature, compounds derived from piperazine often exhibit a range of biological activities. Researchers are exploring its potential as a therapeutic agent that could interact with key neurotransmitters.
  • Potential in Drug Design: The presence of both the aromatic and carbonyl functionalities suggests that this compound may be employed in the development of novel pharmacophores.
  • Research Perspectives: Ongoing studies focus on synthesizing analogs of this compound to enhance its efficacy and optimize its pharmacokinetic properties.
  • Application in Material Science: Beyond medicinal chemistry, compounds like this one are being explored for their potential applications in organic electronics and photonic materials.

The intricate balance of its components underscores the importance of structure-activity relationships (SAR) in drug discovery. As a scientist studying this compound, one might encounter phrases such as, "It is not just the presence of chemical groups, but their spatial arrangement that governs interaction with biological targets." This insight highlights the meticulous nature of pharmaceutical research.

In conclusion, 4-[4-[(2-oxoindolin-3-ylidene)methyl]phenyl]piperazine-1-carbaldehyde stands at the intersection of synthetic organic chemistry and therapeutic innovation, making it a captivating subject for further exploration.

Synonyms
su4984
4-[4-[(2-oxo-1H-indol-3-ylidene)methyl]phenyl]piperazine-1-carbaldehyde
186610-89-9
4-{4-[(2-oxo-1H-indol-3-ylidene)methyl]phenyl}piperazine-1-carbaldehyde