Interesting facts
Exploring 4-[3-(tert-butylamino)-2-hydroxy-propoxy]-1,3-dihydrobenzimidazol-2-one
This compound is a fascinating member of the benzimidazole family, showcasing a blend of structural complexity and biological significance. Here are some intriguing aspects of this compound:
- Pharmacological Potential: Compounds featuring the benzimidazole structure are often investigated for their pharmacological properties, including anti-inflammatory, antifungal, and anticancer activities. The presence of the tert-butylamino group enhances its biological activity.
- Chirality and Isomerism: The presence of hydroxy and amino substituents creates potential for chirality, leading to the possibility of multiple stereoisomers. This can significantly influence the pharmacodynamics and pharmacokinetics of the compound.
- Structure-Activity Relationship (SAR): SAR studies are vital in medicinal chemistry. By modifying the amino and hydroxy groups, scientists can explore how these changes affect the compound's biological activity, aiding in the development of more effective drug candidates.
- Versatile Synthetic Approaches: The synthesis of this compound can involve various methods, including nucleophilic substitutions and coupling reactions. This versatility makes it a valuable target for synthetic chemists aiming to research or produce similar compounds.
- Interdisciplinary Applications: Beyond medicinal chemistry, this compound could find applications in materials science and nanotechnology due to its unique functional groups, which may facilitate interactions in polymer matrices or as ligands in coordination compounds.
As a student of chemistry, uncovering the myriad of reactions and interactions involving this compound can be both a challenging and rewarding endeavor. Understanding these aspects can serve as a pathway to advancing research in drug discovery and material innovation.
Synonyms
Cgp 12177
81047-99-6
Cgp-12177
Cgp 12177A
4-(3-tert-Butylamino-2-hydroxypropoxy)benzimidazol-2-one
4-[3-(tert-butylamino)-2-hydroxypropoxy]-1,3-dihydrobenzimidazol-2-one
Tbhpbo
CHEBI:73288
[3H]CGP 12177
R89UMZ82MJ
CGP12177A
(+/-)-CGP-12177A hydrochloride
2H-Benzimidazol-2-one, 4-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-1,3-dihydro-
2H-Benzimidazol-2-one,4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-1,3-dihydro-
4-[3-(tert-butylamino)-2-hydroxypropoxy]-1,3-dihydro-2H-benzimidazol-2-one
UNII-R89UMZ82MJ
2H-Benzimidazol-2-one, 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-1,3-dihydro-
4-(3-(TERT-BUTYLAMINO)-2-HYDROXYPROPOXY)-1,3-DIHYDROBENZIMIDAZOL-2-ONE
[3H]CGP12177
[3H]-CGP12177
Spectrum_001907
SpecPlus_000776
Spectrum4_000777
CGP-12177A hydrochloride
Lopac0_000372
GTPL532
KBioGR_001194
KBioSS_002444
DivK1c_006872
CHEMBL420746
GTPL5387
SCHEMBL2016211
BDBM25747
KBio1_001816
KBio2_002438
KBio2_005006
KBio2_007574
DTXSID901001733
CGP12177
BDBM50027879
CCG-204467
SDCCGSBI-0050360.P003
NCGC00015184-03
NCGC00015184-04
NCGC00015184-05
NCGC00015184-08
NCGC00025024-02
NCGC00025024-03
(+/-)-CGP-12177
CGP-12177, (+/-)-
L000166
BRD-A34706053-003-01-9
BRD-A40084411-003-07-7
Q27075889
7-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-benzimidazol-2-ol
4-[3-(tert-butylamino)-2-hydroxypropoxy]-2,3-dihydro-1H-1,3-benzodiazol-2-one
4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-1,3-dihydro-2h-benzimidazol-2-one
4-[3-(tert-butylamino)-2-hydroxypropoxy]-2,3-dihydro-1H-1,3-benzodiazol-2-one hydrochloride
Solubility of 4-[3-(tert-butylamino)-2-hydroxy-propoxy]-1,3-dihydrobenzimidazol-2-one
The solubility of 4-[3-(tert-butylamino)-2-hydroxy-propoxy]-1,3-dihydrobenzimidazol-2-one (C16H24N2O3) can be influenced by various factors. Understanding its solubility behavior is crucial for applications in medicinal chemistry and pharmaceutical formulations. Here are some key points to consider:
As a general rule, "solubility is a complex interplay of molecular interactions." Understanding these interactions can help in predicting the behavior of this compound in various solvents, enabling better applications in fields such as pharmaceuticals. Thus, it is essential to carry out empirical solubility testing in relevant media to fully establish its behavior.