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Phenylbutazone

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Identification
Molecular formula
C19H20N2O2
CAS number
50-33-9
IUPAC name
4-(3-oxobutyl)-1,2-diphenyl-pyrazolidine-3,5-dione
State
State

At room temperature, Phenylbutazone is in a solid state.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
150.60
Boiling point (Kelvin)
423.75
General information
Molecular weight
308.37g/mol
Molar mass
308.3730g/mol
Density
1.2350g/cm3
Appearence

Phenylbutazone appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 4-(3-oxobutyl)-1,2-diphenyl-pyrazolidine-3,5-dione

The solubility of 4-(3-oxobutyl)-1,2-diphenyl-pyrazolidine-3,5-dione (C19H20N2O2) can be influenced by several factors:

  • Polar vs Non-Polar Solvents: This compound is expected to demonstrate varying solubility in polar and non-polar solvents. Generally, compounds with significant non-polar characteristics tend to dissolve better in organic solvents like chloroform or hexane.
  • Temperature: Increased temperature often enhances solubility. Therefore, heating the solvent may lead to better dissolution of the compound.
  • pH Levels: As a weakly acidic or basic compound, changes in pH can alter the solubility significantly, influencing ionization states.

In specific solvents, the solubility could be described as follows:

  1. High solubility in organic solvents such as ethanol and acetone.
  2. Limited solubility in water, indicating a hydrophobic character.

As a note, empirical testing is vital, as theoretical predictions might not capture every aspect of solubility. Understanding the solubility characteristics of this compound is crucial for applications in pharmaceuticals and chemical synthesis, where dissolution behavior is a key parameter.


Interesting facts

Interesting Facts about 4-(3-oxobutyl)-1,2-diphenyl-pyrazolidine-3,5-dione

4-(3-oxobutyl)-1,2-diphenyl-pyrazolidine-3,5-dione is a fascinating compound belonging to the class of pyrazolidinones, which are noteworthy for their diverse biological activities. Here are some intriguing aspects of this compound:

  • Role in Pharmacology: Pyrazolidinones have been studied for their anti-inflammatory and analgesic properties. This particular compound could serve as a lead structure for developing new medications.
  • Synthesis Techniques: The synthesis often involves multiple steps, allowing chemists to explore various reaction conditions and approaches, which can enrich their understanding of organic synthesis.
  • Structural Importance: The unique combination of diphenyl and pyrazolidine rings contributes to the compound's potential reactivity and interaction with biological targets, showcasing the importance of molecular architecture in drug design.
  • Potential Applications: Beyond pharmaceuticals, compounds like this one can have applications in agrochemicals or materials science due to their intriguing properties.

The study of such compounds opens the door to innovative scientific research and enhances our understanding of how molecular variations can lead to significant changes in biological activity. As with many compounds featuring heterocyclic structures, their complexity invites ongoing research into their full potential and mechanisms of action.

Furthermore, as the scientific community explores alternatives and advancements in medicinal chemistry, understanding the properties and behaviors of compounds like 4-(3-oxobutyl)-1,2-diphenyl-pyrazolidine-3,5-dione becomes increasingly relevant to our futures in health and technology.

Synonyms
KEBUZONE
ketophenylbutazone
853-34-9
Chetazolidin
Ketazone
Chepirol
Ketason
Recheton
Chetil
Pecnon
4-(3-oxobutyl)-1,2-diphenylpyrazolidine-3,5-dione
Ketophenylbutazonum
kebuzon
Kebuzone [INN]
Hichillos
Kebuzonum
Quebuzona
Keobutane-jade
4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedione
Kebuzonum [INN-Latin]
Quebuzona [INN-Spanish]
kebuzona
CETOPHENYLBUTAZONE
Ketophenylbutazone (JAN)
Chebutan
EINECS 212-715-7
UNII-4VD83UL6Y6
Kebuzone (INN)
BRN 0308507
4VD83UL6Y6
CHEBI:31749
1,2-Diphenyl-4-(gamma-ketobutyl)-3,5-pyrazolidinedione
KEBUZONE [MI]
Copirene
KEBUZONE [MART.]
KEBUZONE [WHO-DD]
1,2-Diphenyl-4-(3'-oxobutyl)-3,5-dioxopyrazolidine
KETOPHENYLBUTAZONE [JAN]
DTXSID00234500
5-24-09-00131 (Beilstein Handbook Reference)
3,5-Pyrazolidinedione, 1,2-diphenyl-4-(3-oxobutyl)-
Kebuzonum (INN-Latin)
chetofenilbutazon
Quebuzona (INN-Spanish)
chetofenilbutazone
KEBUZONE (MART.)
4-(3-oxobutyl)-1,2-di(phenyl)pyrazolidine-3,5-dione
Ketazone; Ketophenylbutazone; Pecnon; Phloguron; Recheton
4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedione; 1,2-Diphenyl-4-(2-acetylethyl)
SCHEMBL231224
1,2-Diphenyl-4-(2-acetylethyl)pyrazolidine-3,5-dione
CHEMBL2107720
EX-A8014H
DTXCID60156991
M01AA06
LGYTZKPVOAIUKX-UHFFFAOYSA-N
AKOS016845857
DB08940
FK24754
NCGC00510940-01
AS-88230
DA-54615
HY-111284
CS-0034815
NS00009672
D01567
G78077
4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedion
Q1105900
212-715-7