Skip to main content

Spironolactone analog

ADVERTISEMENT
Identification
Molecular formula
C21H29FNO
CAS number
None
IUPAC name
4-(3-azaspiro[5.6]dodecan-3-yl)-1-(4-fluorophenyl)butan-1-one
State
State
At room temperature, this compound is typically a solid, consistent with its crystalline powder form.
Melting point (Celsius)
125.00
Melting point (Kelvin)
398.15
Boiling point (Celsius)
422.00
Boiling point (Kelvin)
695.15
General information
Molecular weight
341.47g/mol
Molar mass
341.4650g/mol
Density
1.2345g/cm3
Appearence

This compound typically appears as a white to off-white crystalline powder. The appearance might vary slightly based on purity and form, such as anhydrous or hydrated states.

Comment on solubility

Solubility of 4-(3-azaspiro[5.6]dodecan-3-yl)-1-(4-fluorophenyl)butan-1-one (C21H29FNO)

The solubility of 4-(3-azaspiro[5.6]dodecan-3-yl)-1-(4-fluorophenyl)butan-1-one in various solvents can significantly affect its application in chemical processes and pharmacological contexts. Here are some key points regarding its solubility:

  • Polar Solvents: Typically, compounds with amine functional groups show better solubility in polar solvents like water or ethanol.
  • Non-Polar Solvents: Given the hydrophobic nature of the aromatic and spirocyclic components, expect a degree of solubility in non-polar solvents such as chloroform or hexane.
  • Temperature Influence: Solubility often increases with temperature; hence, understanding the compound's behavior under various thermal conditions can provide clearer insights.
  • pH Dependency: The solubility may also be influenced by the pH of the solution, particularly due to the presence of the amine group, which can become protonated in acidic environments, enhancing solubility.

In conclusion, while the solubility of C21H29FNO may vary widely based on environmental conditions, it is essential to consider these multiple factors when assessing its compatibility for specific uses. The interplay of these factors highlights the complexity of solubility behavior in organic compounds.

Interesting facts

Interesting Facts about 4-(3-Azaspiro[5.6]dodecan-3-yl)-1-(4-fluorophenyl)butan-1-one

This compound, known for its complex structure and intriguing properties, belongs to a class of molecules that has garnered significant attention in medicinal chemistry. Here are some captivating aspects of this compound:

  • Structural Diversity: The presence of the spirocyclic moiety contributes to a unique three-dimensional conformation, unlocking new avenues for interactions with biological targets.
  • Fluorine Substitution: The 4-fluorophenyl group enhances lipophilicity and may improve binding affinity to specific receptors, making it an important consideration in drug design.
  • Potential Therapeutic Applications: Research indicates that compounds with similar structures may exhibit analgesic, anti-inflammatory, and even neuroprotective activities, hinting at possible therapeutic uses.
  • Chirality: The compound might possess chiral centers, offering opportunities for studying enantiomeric effects in biological activity, a critical aspect in pharmacology.
  • Toxicological Profile: Understanding the safety and toxicity of such compounds is vital, as alterations in chemical structure can lead to vastly different biological responses.

The study of compounds like this one exemplifies the intersection of structural chemistry and pharmacology. As researchers continue to explore their potential, it is essential to keep an open mind about how variations in molecular structure can translate into diverse functional outcomes. In the words of discoverers, "The beauty of chemistry lies in its complexity and endless possibilities."


Overall, compounds such as 4-(3-azaspiro[5.6]dodecan-3-yl)-1-(4-fluorophenyl)butan-1-one represent a thrilling frontier in the exploration of novel medicinal agents.

Synonyms
BRN 1348998
BUTYROPHENONE, 4-(3-AZASPIRO(5.6)DODEC-3-YL)-4'-FLUORO-
64-57-3
4-(3-Azaspiro(5.6)dodec-3-yl)-4'-fluoro-butyrophenone
DTXSID00213976
5-20-04-00448 (Beilstein Handbook Reference)
DTXCID30136467