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Spiperone

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Identification
Molecular formula
C23H26FNOS
CAS number
749-02-0
IUPAC name
4-(3-azaspiro[5.5]undecan-3-yl)-1-(4-fluorophenyl)butan-1-one
State
State
At room temperature, spiperone is a solid compound. It is generally stored as a solid crystal or powder for use in various chemical and pharmacological studies.
Melting point (Celsius)
242.00
Melting point (Kelvin)
515.20
Boiling point (Celsius)
427.70
Boiling point (Kelvin)
700.90
General information
Molecular weight
395.53g/mol
Molar mass
395.5270g/mol
Density
1.3030g/cm3
Appearence

Spiperone typically appears as a white or almost white crystalline powder. It is highly soluble in organic solvents and exhibits little to no color.

Comment on solubility

Solubility of 4-(3-azaspiro[5.5]undecan-3-yl)-1-(4-fluorophenyl)butan-1-one

The solubility of the compound 4-(3-azaspiro[5.5]undecan-3-yl)-1-(4-fluorophenyl)butan-1-one (C23H26FNOS) can be influenced by several factors, making it essential to consider both its structural characteristics and the surrounding media. Here are some key points regarding its solubility:

  • Polarity: Given the presence of a fluorine atom and multiple organic functional groups, this compound may exhibit a balance between polar and non-polar regions, potentially affecting its solubility in polar vs. non-polar solvents.
  • Hydrogen bonding: The nitrogen atom in the aza-spiro structure can participate in hydrogen bonding, which might enhance its solubility in polar solvents such as water or alcohol.
  • Solvent interaction: Solubility is likely to vary based on the solvent. For instance, "Like dissolves like" principles apply: it may be more soluble in organic solvents like ethanol or acetone compared to water.
  • Temperature effects: Increasing temperatures generally increase solubility for solids in liquids, hence elevating temperatures could be favorable for its dissolution.

In summary, while the precise solubility of C23H26FNOS may require experimental data for accurate quantification, understanding structural factors and solvent interactions can provide critical insights into its solubility behavior.

Interesting facts

Interesting Facts about 4-(3-azaspiro[5.5]undecan-3-yl)-1-(4-fluorophenyl)butan-1-one

This compound, with its complex structure, belongs to a class of organic molecules known for their potential pharmacological applications. Here are some noteworthy points to consider:

  • Spiraling Design: The term "spiro" in the name indicates a unique bicyclic structure, which often leads to interesting steric and electronic properties that can affect reactivity and biological activity.
  • Aza-Components: The presence of the nitrogen atom in the spirocycle significantly influences the compound's basicity and potential interactions with biological targets. Nitrogen-containing structures can often enhance solubility and permeability in biological systems.
  • Substituent Influence: The fluorine atom attached to the phenyl group may change the compound's electronic properties, potentially enhancing its potency compared to its non-fluorinated counterparts. Fluorine is known for imparting unique characteristics, such as increased metabolic stability.
  • Research Potential: Compounds like this one are often synthesized for their possible roles in drug development, particularly in the field of neuropharmacology. The structural features may offer insights into the design of new therapeutic agents targeting nervous system disorders.
  • Chiral Centers: With multiple chiral centers in the structure, the compound showcases optical isomerism, leading to different enantiomers that may have distinct biological activities. This is a crucial aspect for pharmacokinetics and pharmacodynamics in drug development.

As a chemistry student or scientist, exploring such complex compounds can provide a gateway into cutting-edge research, revealing the dynamic interplay between chemical structure and biological function. The fascinating intricacies associated with the synthesis and application of compounds like 4-(3-azaspiro[5.5]undecan-3-yl)-1-(4-fluorophenyl)butan-1-one underscore the thriving nature of medicinal chemistry.

Synonyms
1-Butanone, 4-(3-azaspiro(5.5)undec-3-yl)-1-(4-fluorophenyl)-
1997-30-4
R-4006
DTXSID00173763