Skip to main content

Fenoldopam

ADVERTISEMENT
Identification
Molecular formula
C16H16ClNO3
CAS number
67227-56-9
IUPAC name
4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol
State
State

At room temperature, fenoldopam is a solid. It is stable under normal temperatures and pressures when kept in a sealed container.

Melting point (Celsius)
245.00
Melting point (Kelvin)
518.00
Boiling point (Celsius)
472.80
Boiling point (Kelvin)
746.00
General information
Molecular weight
338.36g/mol
Molar mass
338.3560g/mol
Density
1.4600g/cm3
Appearence

Fenoldopam is typically presented as a white to off-white crystalline powder, which may appear slightly yellowish under certain conditions.

Comment on solubility

Solubility of 4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol

The solubility of the compound 4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol, with the chemical formula C16H16ClNO3, tends to exhibit specific characteristics influenced by its chemical structure.

Key Points on Solubility:

  • Polarity: This compound consists of various functional groups that may contribute to its polar characteristics, affecting its solubility in polar solvents like water.
  • Solvent Interaction: The presence of the hydroxy group may enhance solubility in alcohols while reducing it in non-polar solvents. Therefore, it may be soluble in organic solvents like ethanol or methanol.
  • pH Dependence: The solubility can vary with changes in pH due to the ionization of the phenolic –OH groups, making it more soluble in alkaline conditions compared to neutral or acidic ones.

In summary, the solubility of this compound is largely determined by its chemical structure, which dictates its behavior in various solvents. To sum up, it could be characterized as:

  1. More soluble in polar solvents than non-polar ones
  2. Exhibiting increased solubility under alkaline conditions
  3. Potentially limited solubility in water, yet soluble in organic solvents

Understanding the solubility of this complex compound is essential for its application in various fields, ranging from pharmaceuticals to material science.

Interesting facts

Interesting Facts about 4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol

This fascinating chemical compound belongs to a diverse class of organic molecules with significant pharmaceutical implications. Its structure exemplifies the complexity that can be achieved in organic chemistry, given that it contains several functional groups and a multi-ring system. Here are some intriguing aspects of this compound:

  • Biological Activity: Compounds like 4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol are often studied for their potential biological activities. Scientists are particularly interested in their role as antioxidants, which can prevent cellular damage.
  • Synthetic Applications: This compound serves as a useful precursor in the synthesis of various medicinal agents. Its multi-faceted structure is beneficial for designing drugs that target specific biochemical pathways.
  • Mechanism of Action: The presence of the hydroxyl group and the dioxo moiety may contribute to its ability to engage in hydrogen bonding, enhancing its reactivity and interactions within biological systems.
  • Research Significance: Emerging studies suggest its effectiveness in combating oxidative stress, making it a compound of interest for developing treatments for a variety of diseases.
  • Multi-functional Groups: The careful arrangement of hydroxyl and benzene rings in its structure opens up numerous avenues for functionalization, potentially leading to new derivatives with enhanced capabilities.

As chemists continue to explore the full potential of 4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol, it embodies the intersection of organic synthesis and medicinal chemistry, showcasing how small changes in molecular structure can lead to significant shifts in biological function. The study of such compounds not only enhances our understanding of chemistry but also paves the way for innovative therapeutic applications.

Synonyms
PHENOL RED
phenolsulfonphthalein
143-74-8
Fenolipuna
Sulfonphthal
Sulphental
Sulphonthal
Phenolsulphonphthalein
Phenolred
Phenolsulfonephthalein
PSP (indicator)
Phenol, 4,4'-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis-
Phenosulfophthalein
3,3-Bis(4-hydroxyphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide
MFCD00003552
NSC 10459
NSC-10459
UNII-I6G9Y0J1OJ
NSC10459
EINECS 205-609-7
I6G9Y0J1OJ
Phenol red, PSP
Phenol red indicator
BRN 0326470
Phenolsulfonphthalein [JAN:NF]
DTXSID8022408
4,4'-(1,1-dioxido-3H-2,1-benzoxathiole-3,3-diyl)diphenol
4,4'-(3H-2,1-Benzoxathiol-3-ylidene)diphenol S,S-dioxide
Phenol, 4,4-(3H-2,1-benzoxathiol-3-ylidene)di-, S-S-dioxide
Phenolsulfonphthalein (TN)
3H-2,1-Benzoxathiole, 3,3-bis(4-hydroxyphenyl)-, 1,1-dioxide
DTXCID202408
CHEBI:31991
Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis-, S,S-dioxide
Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)di-, S,S-dioxide
Phenolsulfonphthalein (JP17/NF)
PHENOLSULFONPHTHALEIN [MI]
Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis-, (S,S-dioxide)
PHENOLSULFONPHTHALEIN [JAN]
4-[3-(4-Hydroxyphenyl)-1,1-dioxo-2,1lambda6-benzoxathiol-3-yl]phenol
5-19-03-00457 (Beilstein Handbook Reference)
P. S. P.
PHENOLSULFONPHTHALEIN [VANDF]
PHENOLSULFONPHTHALEIN [MART.]
PHENOLSULFONPHTHALEIN [WHO-DD]
NCGC00013109-03
3,3-bis(p-hydroxyphenyl)-3H-2,1-benzoxathiole 1,1-dioxide
PHENOLSULFONPHTHALEIN [EP MONOGRAPH]
3,3-bis(4-hydroxyphenyl)-3H-2,1??-benzoxathiole-1,1-dione
4,4'-(3H,2,1-Benzoxathiol-3-ylidene)bisphenol S,S-dioxide
4,4'-(3H-2,1-benzoxathiol-3-ylidene)bisphenol S,S-dioxide
Phenol-red
3,3-BIS(4-HYDROXYPHENYL)-3H-2,1-BENZOXATHIOLE 1,1-DIOXIDE
PHENOLSULFONPHTHALEIN (MART.)
alpha-hydroxy-alpha,alpha-bis(p-hydroxyphenyl)-o-toluenesulfonic acid gamma-sultone
CAS-143-74-8
PHENOLSULFONPHTHALEIN (EP MONOGRAPH)
2-(Bis(4-hydroxyphenyl)methyliumyl)benzenesulfonate
2-[Bis(4-hydroxyphenyl)methyliumyl]benzenesulfonate
C19H14O5S
Phenolsulfonphthalein; 3,3-bis(4-hydroxyphenyl)-3H-2,1-benzoxathiole 1,1-dioxide; PSP
Phenol red solution
phenolsulphonephthalein
Phenol red ACS grade
Phenol Red, ACS reagent
NCIStruc1_001090
NCIStruc2_000839
SCHEMBL17836
BIDD:ER0046
CHEMBL258921
Phenol Red, JIS special grade
Phenol Red, p.a., ACS reagent
3,3-bis(4-hydroxyphenyl)benzo[c]1,2-oxathiolene-1,1-dione
HY-D0169
NCI10459
PHENOLSULFONPHTHALEIN [INCI]
Tox21_110012
Tox21_303570
BBL000596
CCG-36909
NCGC00013109
STK364540
4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1$l^{6}-benzoxathiol-3-yl]phenol
AKOS000592531
Tox21_110012_1
DB13212
NCGC00013109-01
NCGC00013109-02
NCGC00096230-01
NCGC00257424-01
AC-18338
NCI60_000111
VS-00652
DB-042702
CS-0010076
NS00019704
P0100
P0101
P0703
D01200
D70382
AB00444024_03
EN300-6492950
Q418719
SR-01000357546
3H-2, 3,3-bis(4-hydroxyphenyl)-, 1,1-dioxide
SR-01000357546-1
4,4'(3H2,1Benzoxathiol3ylidene)diphenol S,Sdioxide
BRD-K79892937-001-01-7
BRD-K79892937-001-02-5
Phenol red solution (liquid, 0.5%, sterile-filtered)
Phenol, 4,4(3H2,1benzoxathiol3ylidene)di, SSdioxide
Z56768517
3H2,1Benzoxathiole, 3,3bis(4hydroxyphenyl), 1,1dioxide
Phenol Red, powder, BioReagent, suitable for cell culture
4,4'-(3H-2,1-Benzoxathiol-3-ylidene)diphenol, S,S-dioxide-
Phenol,4'-(3H-2,1-benzoxathiol-3-ylidene)bis-, S,S-dioxide
Phenol,4'-(3H-2,1-benzoxathiol-3-ylidene)di-, S,S-dioxide
Phenol,4-(3H-2,1-benzoxathiol-3-ylidene)di-, S,S-dioxide
Phenol,4-(3H-2,1-benzoxathiol-3-ylidene)di-, S-S-dioxide
3,3-bis(4-hydroxyphenyl)-3H-2,1lambda6-benzoxathiole-1,1-dione
Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis-,S,S-dioxide (9CI)